Kev npaj cov tshuaj hydroxypropyl methylcellulose (HPMC) txheej txheej yuav tsum tau ua tib zoo saib xyuas kom meej.HPMC feem ntau yog siv los ua cov khoom siv zaj duab xis txheej hauv kev lag luam tshuaj thiab zaub mov.Cov txheej txheem txheej yog siv rau cov ntsiav tshuaj lossis granules los muab cov txheej txheem tiv thaiv, txhim kho qhov tsos, thiab pab kom nqos tau.
1. Taw qhia rau HPMC txheej:
Hydroxypropylmethylcellulose (HPMC) yog cellulose-raws li polymer muab los ntawm cov nroj tsuag fibers.Vim nws cov yeeb yaj kiab-suab thiab thickening zog, nws yog dav siv nyob rau hauv zaj duab xis coatings nyob rau hauv kev lag luam tshuaj thiab zaub mov.
2. Cov ntaub ntawv uas yuav tsum tau muaj:
Hydroxypropyl methylcellulose hmoov
Purify dej
Yas lossis stainless hlau ntim
Cov khoom siv stirring (xws li sib nqus stirrer)
Ntsuas ntsuas ( nplai, ntsuas lub tog raj kheej)
pH ntsuas
Yas lossis stainless hlau txheej lauj kaub
Cua kub qhov cub
3. program:
Ntsuas lub HPMC:
Ntsuas qhov ntsuas qhov xav tau ntawm HPMC hmoov raws li qhov xav tau txheej txheej.Concentrations feem ntau yog nyob nruab nrab ntawm 2% thiab 10%.
Npaj dej purified:
Siv cov dej huv huv kom paub meej tias nws tsis muaj impurities uas tuaj yeem cuam tshuam qhov zoo ntawm cov txheej txheem.Cov dej yuav tsum nyob ntawm chav tsev kub.
Dispersion ntawm HPMC:
Maj mam ntxiv cov hmoov HPMC uas hnyav rau cov dej huv thaum nplawm tas li.Qhov no tiv thaiv clumps los ntawm kev tsim.
Do:
Do cov sib tov siv cov sib nqus stirrer los yog lwm yam khoom siv stirring kom txog thaum HPMC hmoov yog tag nrho dispersed nyob rau hauv dej.
Kev kho pH:
Ntsuas pH ntawm cov tshuaj HPMC siv lub ntsuas pH.Yog tias tsim nyog, pH tuaj yeem hloov kho los ntawm kev ntxiv me me ntawm cov kua qaub lossis lub hauv paus raws li.Qhov zoo tshaj pH rau zaj duab xis txheej yog feem ntau nyob rau hauv thaj tsam ntawm 5.0 txog 7.0.
Moisturizing thiab aging:
Cov tshuaj HPMC tso cai rau hydrate thiab hnub nyoog rau lub sijhawm tshwj xeeb.Qhov no txhim kho cov yeeb yaj kiab tsim cov khoom.Lub sijhawm laus tuaj yeem sib txawv tab sis feem ntau yog nyob rau hauv thaj tsam ntawm 2 txog 24 teev.
lim:
Lim cov tshuaj HPMC kom tshem tawm tej yam uas tsis tau muab tshem tawm los yog impurities.Cov kauj ruam no yog qhov tseem ceeb kom tau txais cov txheej txheem du thiab meej.
Kev kho viscosity:
Ntsuas cov viscosity ntawm cov tshuaj thiab kho nws mus rau qib uas xav tau.Viscosity cuam tshuam rau uniformity thiab thickness ntawm txheej.
Test compatibility:
Ntsuam xyuas cov kev sib raug zoo ntawm cov txheej txheem nrog cov substrate (cov ntsiav tshuaj lossis granules) kom ntseeg tau tias muaj adhesion thiab tsim cov yeeb yaj kiab.
Txheej txheej txheej:
Siv cov txheej txheej tsim nyog thiab siv lub tshuab txheej los siv cov tshuaj HPMC txheej rau cov ntsiav tshuaj lossis granules.Kho lub lauj kaub ceev thiab cua kub kom pom txheej txheej.
ziab:
Cov ntsiav tshuaj coated los yog granules yog qhuav nyob rau hauv ib tug kub-tswj cua kub qhov cub kom txog rau thaum lub xav tau txheej thickness tiav.
QC:
Ua cov kev tswj xyuas zoo ntawm cov khoom coated nrog rau cov tsos, thickness thiab dissolution zog.
4. nyob rau hauv xaus:
Kev npaj ntawm HPMC txheej daws teeb meem suav nrog ntau cov kauj ruam meej los xyuas kom meej qhov zoo thiab ua tau zoo ntawm txheej.Kev ua raws li cov txheej txheem sau tseg thiab kev ntsuas kev tswj hwm zoo yog qhov tseem ceeb kom tau txais txiaj ntsig zoo ib yam thiab txhim khu kev qha hauv kev lag luam tshuaj thiab zaub mov.Ib txwm ua raws li Kev Ua Haujlwm Zoo (GMP) thiab cov lus qhia ntsig txog thaum txheej txheej txheej txheej.
Post lub sij hawm: Jan-18-2024