Hydroxypropylmethylcellulose (HPMC) is a cellulose derivative inoshandiswa zvakanyanya mumaindasitiri akasiyana semushonga, chikafu uye zvizorwa.Iyo multifunctional polymer inogona kugadzira gel pasi pemamwe mamiriro, uye tembiricha yayo yegel chinhu chakakosha.
HPMC gelation tembiricha inoreva tembiricha apo polima inopinda nhanho yekuchinja kubva pamhinduro kuenda kune gel state.Iyo gelation process inokanganiswa nezvakasiyana siyana, kusanganisira kusungirirwa kweHPMC mumhinduro, kuvapo kwezvimwe zvinhu, uye mamiriro ezvakatipoteredza.
Iyo tembiricha yegelation yeHPMC inokanganiswa nedhigirii rekutsiva hydroxypropyl uye methyl mapoka pane cellulose musana.Madhigirii epamusoro ekutsiva anowanzo konzera kuderera kwe tembiricha ye gelation.Uyezve, kusungirirwa kweHPMC mumhinduro kunoitawo basa rakakosha.Kunyanya kuwanda kunowanzo konzera kudzikira kwekushisa kwegelling.
Iyo gelation mechanism yeHPMC inosanganisira kuumbwa kwetatu-dimensional network yemaketani epolymer kuburikidza nekubatana kweintermolecular (semuenzaniso, hydrogen bonding).Iyi network inogadzirisa inogadzirisa zvinhu zvemuviri zvegel, zvakadai se viscosity uye simba remagetsi.
Kunzwisisa tembiricha yegelation yeHPMC yakakosha kune akasiyana maapplication.Semuenzaniso, mumunda wemishonga, zvakakosha pakugadzirwa kwemaitiro anodzorwa-anoburitswa ekupa zvinodhaka.Tembiricha yeGelation inosarudza nguva inotora kuti gel matrix iumbe mudumbu rekudya, zvichikanganisa kuburitsa zvinodhaka kinetics.
Muchikafu uye cosmetic magadzirirwo, HPMC gel tembiricha yakakosha kudzora chigadzirwa magadzirirwo uye kugadzikana.Inobata zvinhu zvakadai sekuravira, kutaridzika uye hupenyu hwesherufu.HPMC inowanzo shandiswa seyakakora kana gelling mumiririri mumaindasitiri aya.
Matanho akati wandei anogona kushandiswa kuyera nekudzora tembiricha yegel yeHPMC.Differential scanning calorimetry (DSC) uye rheological zvidzidzo inzira dzakajairika dzekutaridza kupisa uye mashandiro emagetsi eHPMC gels.Nekugadzirisa zvinhu zvakaita sekutarisa uye kuvapo kwezvinowedzera, vagadziri vanogona kugadzirisa tembiricha yegelation kuti isangane nezvinodiwa zvekushandisa.
Muchidimbu, hydroxypropyl methylcellulose gel tembiricha ndiyo yakakosha parameter kune akasiyana maindasitiri.Mhedzisiro yaro pazvivakwa zvegel inoita kuti ive chinhu chakakosha chekushandisa kubva kumishonga kusvika kune chikafu uye zvekuzora.Kunzwisisa izvo zvinopesvedzera HPMC gel tembiricha inobvumira kunyatso kudzora uye optimization yekushandiswa kwayo mumhando dzakasiyana.
Nguva yekutumira: Zvita-11-2023