Hydroxypropylmethylcellulose (HPMC) yog cellulose derivative siv dav hauv ntau yam lag luam xws li tshuaj, khoom noj khoom haus thiab tshuaj pleev ib ce.Nws yog ib tug multifunctional polymer uas muaj peev xwm tsim gel nyob rau hauv tej yam kev mob, thiab nws gel kub yog ib qho tseem ceeb khoom.
HPMC gelation kub yog hais txog qhov kub thiab txias uas cov polymer tau hloov mus rau theem hloov ntawm cov tshuaj mus rau lub xeev gel.Cov txheej txheem gelation raug cuam tshuam los ntawm ntau yam, suav nrog qhov concentration ntawm HPMC hauv cov tshuaj, muaj lwm yam tshuaj, thiab ib puag ncig.
Lub gelation kub ntawm HPMC cuam tshuam los ntawm qib ntawm kev hloov ntawm hydroxypropyl thiab methyl pawg ntawm cov pob txha cellulose.Qib siab ntawm kev hloov pauv feem ntau ua rau qis gelation kub.Tsis tas li ntawd, qhov concentration ntawm HPMC hauv kev daws kuj tseem ua lub luag haujlwm tseem ceeb.Cov concentration ntau dua feem ntau ua rau qis gelling kub.
Lub gelation mechanism ntawm HPMC suav nrog kev tsim ntawm peb-dimensional network ntawm polymer chains los ntawm kev sib koom ua ke (xws li, hydrogen bonding).Cov qauv network no txiav txim siab lub cev lub cev ntawm cov gel, xws li viscosity thiab txhua yam muaj zog.
Nkag siab txog qhov kub thiab txias ntawm HPMC yog qhov tseem ceeb rau ntau yam kev siv.Piv txwv li, nyob rau hauv kev lag luam tshuaj, nws yog ib qho tseem ceeb rau txoj kev loj hlob ntawm kev tswj-tso tshuaj xa cov tshuab.Gelation kub txiav txim siab lub sij hawm nws yuav siv sij hawm rau gel matrix tsim nyob rau hauv lub digestive ib ntsuj av, yog li cuam tshuam rau cov tshuaj tso tawm kinetics.
Hauv cov khoom noj thiab tshuaj pleev ib ce, HPMC gel kub yog qhov tseem ceeb los tswj cov khoom zoo nkauj thiab ruaj khov.Nws cuam tshuam rau yam xws li saj, tsos thiab lub neej txee.HPMC feem ntau yog siv los ua cov thickener lossis gelling tus neeg sawv cev hauv cov kev lag luam no.
Ntau cov txheej txheem tuaj yeem siv los ntsuas thiab tswj cov gel kub ntawm HPMC.Differential scanning calorimetry (DSC) thiab kev tshawb fawb rheological yog ib txoj hauv kev los qhia cov thermal thiab mechanical zog ntawm HPMC gels.Los ntawm kev kho tej yam xws li concentration thiab muaj cov additives, formulators yuav tailor gelation kub kom tau raws li tej kev thov.
Hauv cov ntsiab lus, hydroxypropyl methylcellulose gel qhov kub thiab txias yog qhov tseem ceeb rau ntau yam kev lag luam.Nws cov nyhuv ntawm cov khoom siv gel ua rau nws muaj txiaj ntsig zoo rau cov ntawv thov xws li tshuaj mus rau zaub mov thiab tshuaj pleev ib ce.Kev nkag siab txog yam tseem ceeb uas cuam tshuam rau HPMC gel qhov kub thiab txias tso cai rau kev tswj hwm thiab kev ua kom zoo ntawm nws txoj kev siv hauv cov qauv sib txawv.
Lub sij hawm xa tuaj: Dec-11-2023