Hydroxypropylmethylcellulose (HPMC) bụ cellulose ether nke a na-ejikarị eme ihe n'ọtụtụ ụlọ ọrụ dịka ọgwụ, ihe ịchọ mma, nri, na ihe owuwu.N'ihi ngbanwe ya na ihe bara uru, HPMC aghọwo ihe na-ewu ewu n'ụdị dị iche iche.Ugbu a, enwere ọtụtụ ụdị HPMC n'ahịa, nke ọ bụla nwere akụrụngwa na ngwa pụrụ iche.
HPMC bụ cellulose polima emezigharịrị kemịkalụ enwetara site n'imeghachi cellulose na methyl chloride na propylene oxide.Mmeghachi omume a na-ewebata methyl na hydroxypropyl dị iche iche n'ime usoro cellulose, na-eme ka mmiri na-edozi mmiri, nke na-abụghị ionic na polymer na-arụ ọrụ dị elu.Agbanyeghị, ụdị HPMC dị iche iche nwere ogo dị iche iche nke nnọchi (DS) nke otu methyl na hydroxypropyl, nke na-ekpebi njirimara anụ ahụ na kemịkal ha.
N'ozuzu, ngwaahịa HPMC bụ nkewa dịka viscosity na uru DS siri dị.Viscosity bụ ihe dị mkpa ihe onwunwe nke HPMC dị ka ọ na-emetụta ngwaahịa si solubility, film akpụ ike na ndim ike.N'aka nke ọzọ, uru DS na-ekpebi ogo nke nnọchi polymer na ya mere ogo hydrophobicity nke ụdị HPMC.Ya mere, ụdị HPMC dị iche iche na-enweta site na mgbanwe dị na viscosity ha na ụkpụrụ DS.N'okpuru bụ ụdị HPMC kachasị na otu ha si dị iche.
1. Ọkwa HPMC nkịtị
HPMC nkịtị nwere methyl DS sitere na 0.8 ruo 2.0 yana hydroxypropyl DS sitere na 0.05 ruo 0.3.Ụdị HPMC a dị n'ọtụtụ ọkwa viscosity site na 3cps ruo 200,000cps.HPMC nkịtị nwere ezigbo solubility na mmiri ma mepụta ngwọta doro anya, na-eme ka ọ dabara maka ngwa dị iche iche na ụlọ ọrụ nri, ọgwụ na ịchọ mma.A na-ejikarị HPMC ndị dị otú ahụ eme ihe dị ka ndị na-eme ihe nkiri, ndị na-agba agba, emulsifiers na stabilizers na nri na ihe ịchọ mma.
2. Low nnọchi HPMC
HPMC dị ala dochie anya nwere ogo methyl na hydroxypropyl dị ala karịa ọkwa HPMC oge niile.Ụdị HPMC a nwere methyl DS sitere na 0.2 ruo 1.5 yana hydroxypropyl DS sitere na 0.01 ruo 0.2.Ngwaahịa HPMC dị ala nwere viscosity dị ala, na-adịkarị n'etiti 3-400cps, na-eguzogidekwa nnu na enzymes nke ukwuu.Ihe ndị a na-eme ka HPMC dị ala dabara adaba maka ngwaahịa nri dị ka mmiri ara ehi, ebe a na-eme achịcha na ngwaahịa anụ.Tụkwasị na nke a, a na-ejikwa HPMC dị ala dochie anya dị ka ihe nkpuchi, nkwụsịtụ na mbadamba mbadamba na ụlọ ọrụ ọgwụ.
3. High nnọchi HPMC
Ọkwa dị elu nke nnọchi HPMC nwere ogo dị elu nke nnọchi methyl na hydroxypropyl karịa ọkwa HPMC nkịtị.Ụdị HPMC a nwere methyl DS sitere na 1.5 ruo 2.5 yana hydroxypropyl DS sitere na 0.1 ruo 0.5.Ngwaahịa HPMC etinyere nke ukwuu nwere viscosity dị elu, sitere na 100,000cps ruo 200,000cps, ma nwee ihe njide mmiri siri ike.Ngwongwo ndị a na-eme ka HPMC nọchiri anya nke ukwuu maka ojiji na mpaghara ihe owuwu, dị ka ngwaahịa simenti, mkpuchi na nrapado.A na-ejikwa HPMC nọchiri anya nke ukwuu dị ka ihe na-ekekọta, thickener na onye ntọhapụ na ụlọ ọrụ ọgwụ.
4. Methoxy-Ethoxy HPMC
Methoxy-Ethoxy HPMC bụ ụdị HPMC emebere nke ọma nwere nnukwu ngbanwe ethoxy.Otu ethoxy dị iche iche na-abawanye hydrophobicity nke HPMC, na-eme ka ọ ghara ịdị nro na mmiri karịa ọkwa HPMC mgbe niile.Site na methyl DS sitere na 1.5 ruo 2.5 yana ethoxy DS sitere na 0.4 ruo 1.2, methoxy-ethoxy HPMC dị mma maka iji ngwaahịa sitere na mmanụ dị ka ihe ịchọ mma, agba na mkpuchi.Ụdị HPMC a na-emepụta ihe nkiri kwụsiri ike na otu nke na-enye ọmarịcha, na-egbuke egbuke ruo na ngwaahịa ikpeazụ.
5. HPMC granular
HPMC granular bụ ụdị HPMC nwere ntakịrị nha, nke na-adịkarị n'etiti 100-200 microns.A na-eji HPMC granular na ụlọ ọrụ na-emepụta ọgwụ dị ka ihe nkedo mbadamba, ihe na-agbasasị na ihe ntọhapụ na-adịgide adịgide.The obere urughuru size nke HPMC ahụ na-enye ohere maka ọbụna nkesa nke Efrata, dapụtara na a na-agbanwe agbanwe na a pụrụ ịdabere na ngwaahịa.HPMC granular nwere methyl DS sitere na 0.7 ruo 1.6 yana hydroxypropyl DS sitere na 0.1 ruo 0.3.
Hydroxypropylmethylcellulose (HPMC) bụ polymer multifunctional nwere ọtụtụ ngwa dị iche iche na ụlọ ọrụ dị iche iche.A na-ekewa ụdị HPMC dabere na viscosity na uru DS, nke na-ekpebi njirimara anụ ahụ na kemịkal ha.HPMC ọkwa oge niile, HPMC dị ala, nnọchi elu HPMC, methoxyethoxy HPMC na granular HPMC bụ ụdị HPMC a na-ahụkarị.Ịghọta ọdịiche dị n'etiti ụdị ndị a ga-ekwe ka ndị na-emepụta ihe na-erigbu ike zuru oke nke HPMC iji mepụta ngwaahịa dị elu na njedebe dị ike.
Oge nzipu: Sep-06-2023