Ko Sodium Carboxymethyl Cellulose Inokuvadza Muviri Wevanhu?

Sodium carboxymethyl cellulose (CMC) inowanzoonekwa seyakachengeteka (GRAS) kuti ishandiswe nevakuru vane masimba vakaita seFood and Drug Administration (FDA) muUnited States neEuropean Food Safety Authority (EFSA) muEurope kana ichishandiswa zvinoenderana neyakasimbiswa. nhungamiro dzekuchengetedza uye mukati memiganhu inobvumidzwa.Heino tarisiro yezvekuchengetedza kufunga kwakabatana ne sodium carboxymethyl cellulose:

1. Regulatory Mvumo: CMC inotenderwa kushandiswa sekuwedzera kwechikafu munyika zhinji pasi rese, kusanganisira United States, European Union, Canada, Australia, neJapan.Iyo yakanyorwa neakasiyana siyana anodzora masangano seanobvumidzwa ekuwedzera echikafu ane chaiwo mashandisirwo emuganho uye zvakatemwa.
2. Toxicological Zvidzidzo: Zvakawanda toxicological zvidzidzo zvakaitwa kuongorora kuchengetedzeka kweCMC pakudyiwa kwevanhu.Zvidzidzo izvi zvinosanganisira acute, subchronic, uye chisingaperi chepfu bvunzo, pamwe ne mutagenicity, genotoxicity, uye carcinogenicity ongororo.Zvichienderana nedata riripo, CMC inoonekwa seyakachengeteka kudyiwa nevanhu pamatanho anotenderwa.
3. Inogamuchirwa Zuva Nezuva Intake (ADI): Masangano anodzora akagadzira zvinogamuchirwa zuva nezuva kudya (ADI) kukosha kweCMC zvichibva pane toxicological zvidzidzo uye kuchengetedzwa kwekuongorora.Iyo ADI inomiririra huwandu hweCMC hunogona kudyiwa zuva nezuva kwehupenyu hwese pasina njodzi yehutano.Mitemo yeADI inosiyana pakati pemasangano ekutonga uye inoratidzwa maererano nemamilligrams pakirogiramu yehuremu hwemuviri pazuva (mg/kg bw/day).
4. Allergenicity: CMC inotorwa kubva ku cellulose, inowanzoitika inowanzoitika polysaccharide inowanikwa muchirimwa sero madziro.Hazvizivikanwe kuti zvinokonzeresa kusawirirana muhuwandu hwevanhu.Nekudaro, vanhu vane zvinozivikanwa allergies kana sensitivities kune cellulose derivatives vanofanirwa kungwarira uye kubvunza nyanzvi dzehutano vasati vadya zvigadzirwa zvine CMC.
5. Digestive Chengetedzo: CMC haibatiki negayo remunhu uye inopfuura nemudumbu remudumbu isina kugadzirwa.Inofungidzirwa isiri-chepfu uye isingatsamwiri kune digestive mucosa.Nekudaro, kunyanyisa kunwa CMC kana zvimwe zvinobva kune cellulose zvinogona kukonzera kusagadzikana kwemudumbu, kuzvimba, kana manyoka mune vamwe vanhu.
6. Kudyidzana neMishonga: CMC haizivikanwe kudyidzana nemishonga kana kukanganisa kunyura kwavo mudumbu remukati.Iyo inoonekwa seinopindirana neakawanda emishonga maumbirwo uye inowanzoshandiswa sechinhu chinobatsira mumuromo mafomu emuyero akadai semapiritsi, capsules, uye kumiswa.
7. Kuchengetedzwa Kwemamiriro Ekunze: CMC inodedera uye ine hushamwari kwezvakatipoteredza, sezvo ichitorwa kubva kune anogona kudzokororwa masosi akadai sehuni pulp kana donje cellulose.Inoputsika zvakasununguka munharaunda kuburikidza nekuita kwe microbial uye haiunganidzi muvhu kana masystem emvura.

sodium carboxymethyl cellulose (CMC) inoonekwa seyakachengeteka kushandiswa kana ichishandiswa zvinoenderana nemirairo yemitemo uye yakasimbiswa kuchengetedza zviyero.Yakave yakadzidzwa zvakanyanya nekuda kwehupfu hwayo, allergenicity, kugaya kuchengetedzwa, uye kukanganisa kwezvakatipoteredza, uye yakatenderwa kushandiswa sekuwedzera kwechikafu uye mushonga wemishonga munyika zhinji pasi rese.Sezvinoita chero chinongedzo chechikafu kana chekuwedzera, vanhu vanofanirwa kushandisa zvigadzirwa zvine CMC zvine mwero sechikamu chekudya kwakaringana uye kubvunza nyanzvi dzehutano kana vaine zvirambidzo zvechikafu kana zvinetso zvekurapa.