Sodium Carboxymethyl Cellulose puas tsim kev puas tsuaj rau tib neeg lub cev?

Sodium carboxymethyl cellulose (CMC) feem ntau suav hais tias muaj kev nyab xeeb (GRAS) rau kev noj los ntawm cov cai tswj hwm xws li Food and Drug Administration (FDA) hauv Tebchaws Meskas thiab European Food Safety Authority (EFSA) hauv Tebchaws Europe thaum siv raws li tsim los. cov txheej txheem kev nyab xeeb thiab nyob rau hauv cov kev txwv tso cai.Ntawm no yog ib qho kev piav qhia ntawm kev saib xyuas kev nyab xeeb cuam tshuam nrog sodium carboxymethyl cellulose:

1. Kev Pom Zoo Kev Pom Zoo: CMC tau pom zoo siv los ua zaub mov ntxiv hauv ntau lub tebchaws thoob ntiaj teb, suav nrog Tebchaws Meskas, European Union, Canada, Australia, thiab Nyij Pooj.Nws tau teev nrog ntau lub koom haum tswj hwm raws li kev tso cai noj zaub mov ntxiv nrog cov kev txwv tshwj xeeb thiab kev siv tshwj xeeb.
2. Kev Tshawb Fawb Txog Kev Noj Qab Haus Huv: Kev tshawb fawb toxicological ntau tau ua los ntsuas kev nyab xeeb ntawm CMC rau tib neeg noj.Cov kev tshawb fawb no suav nrog kev kuaj mob hnyav, subchronic, thiab mob toxicity, nrog rau kev hloov pauv, genotoxicity, thiab kev ntsuas carcinogenicity.Raws li cov ntaub ntawv muaj, CMC suav hais tias muaj kev nyab xeeb rau tib neeg noj nyob rau theem tso cai.
3. Txais Kev Noj Qab Haus Huv Txhua Hnub (ADI): Cov koom haum tswj hwm tau tsim cov txiaj ntsig tau txais txiaj ntsig txhua hnub (ADI) rau CMC raws li kev tshawb fawb toxicological thiab kev ntsuas kev nyab xeeb.ADI sawv cev rau tus nqi ntawm CMC uas tuaj yeem noj txhua hnub hauv lub neej yam tsis muaj kev pheej hmoo rau kev noj qab haus huv.ADI qhov tseem ceeb sib txawv ntawm cov koom haum tswj hwm thiab tau hais txog milligrams ib kilogram ntawm lub cev hnyav ib hnub (mg / kg bw / hnub).
4. Allergenicity: CMC yog muab los ntawm cellulose, ib txwm tshwm sim polysaccharide pom nyob rau hauv cov nroj tsuag cell phab ntsa.Nws tsis paub tias yuav ua rau muaj kev tsis haum tshuaj rau cov pej xeem.Txawm li cas los xij, cov tib neeg uas paub txog kev ua xua lossis rhiab heev rau cellulose derivatives yuav tsum tau ceev faj thiab sab laj cov kws kho mob ua ntej noj cov khoom uas muaj CMC.
5. Kev Nyab Xeeb Kev Nyab Xeeb: CMC tsis nqus los ntawm tib neeg lub plab zom mov thiab dhau los ntawm txoj hnyuv tsis tau metabolized.Nws suav hais tias yog tsis muaj tshuaj lom thiab tsis ua rau mob plab hnyuv mucosa.Txawm li cas los xij, kev noj ntau dhau ntawm CMC lossis lwm yam cellulose derivatives tuaj yeem ua rau mob plab hnyuv, tsam plab, lossis raws plab hauv qee tus neeg.
6. Kev cuam tshuam nrog cov tshuaj: CMC tsis paub tias cuam tshuam nrog cov tshuaj lossis cuam tshuam rau lawv qhov nqus hauv plab hnyuv.Nws yog suav hais tias yog sib xws nrog feem ntau cov tshuaj formulations thiab feem ntau yog siv raws li ib tug excipient nyob rau hauv lub qhov ncauj noj cov ntaub ntawv xws li ntsiav tshuaj, tsiav tshuaj, thiab suspensions.
7. Ib puag ncig kev nyab xeeb: CMC yog biodegradable thiab ib puag ncig tus phooj ywg, vim nws yog muab los ntawm cov khoom siv txuas ntxiv xws li ntoo pulp lossis paj rwb cellulose.Nws lov ib txwm nyob rau hauv ib puag ncig los ntawm kev ua microbial thiab tsis sib sau hauv av lossis dej.

sodium carboxymethyl cellulose (CMC) yog suav tias yog kev nyab xeeb rau kev noj thaum siv raws li cov kev cai tswj hwm thiab tsim qauv kev nyab xeeb.Nws tau raug tshawb fawb dav dav rau nws cov tshuaj lom neeg, kev ua xua, kev nyab xeeb ntawm plab zom mov, thiab kev cuam tshuam ib puag ncig, thiab tau pom zoo siv los ua cov khoom noj khoom haus thiab tshuaj ntxiv hauv ntau lub tebchaws thoob ntiaj teb.Raws li nrog rau cov khoom noj khoom haus lossis cov khoom ntxiv, cov tib neeg yuav tsum tau noj CMC-muaj cov khoom lag luam hauv nruab nrab raws li ib feem ntawm kev noj zaub mov zoo thiab sab laj nrog kws kho mob yog tias lawv muaj kev txwv tshwj xeeb rau kev noj haus lossis kev txhawj xeeb txog kev kho mob.