Sodium Carboxymethyl Cellulose ọ na-emerụ ahụ mmadụ?

A na-ahụta sodium carboxymethyl cellulose (CMC) dị ka nchekwa (GRAS) maka oriri site n'aka ndị na-ahụ maka nchịkwa dịka nri na ọgwụ ọjọọ (FDA) na United States na European Food Safety Authority (EFSA) na Europe mgbe ejiri ya dabere na ntọala siri ike. ntuziaka nchekwa yana n'ime oke ekwere.Nke a bụ nkọwapụta nke ihe nchekwa metụtara sodium carboxymethyl cellulose:

1. Nkwenye usoro iwu: A kwadoro CMC maka iji dị ka ihe mgbakwunye nri n'ọtụtụ mba n'ụwa nile, gụnyere United States, European Union, Canada, Australia, na Japan.Edepụtara ya na ụlọ ọrụ nhazi dị iche iche dị ka ihe mgbakwunye nri anabatara nwere oke ojiji yana nkọwapụta.
2. Ọmụmụ ihe na-egbu egbu: A na-eme nchọpụta toxicological buru ibu iji chọpụta nchekwa nke CMC maka oriri mmadụ.Ọmụmụ ihe ndị a na-agụnye nnukwu, subchronic na ule toxicity na-adịghị ala ala, yana mutagenicity, genotoxicity, na nyocha carcinogenicity.Dabere na data dị, a na-ahụta CMC dị ka nchekwa maka oriri mmadụ na ọkwa ikike.
3. Nri kwa ụbọchị anabatara (ADI): Ụlọ ọrụ nchịkwa eguzobewo ụkpụrụ oriri kwa ụbọchị (ADI) nke a na-anakwere maka CMC dabere na nchọpụta toxicological na nyocha nchekwa.ADI na-anọchite anya ọnụọgụ CMC nke a ga-eri kwa ụbọchị n'ogologo ndụ na-enweghị ihe ize ndụ maka ahụike.Ụkpụrụ ADI na-adịgasị iche n'etiti ụlọ ọrụ nhazi ma gosipụta ya na milligrams kwa kilogram nke ịdị arọ ahụ kwa ụbọchị (mg/kg bw / day).
4. Allergenicity: CMC sitere na cellulose, polysaccharide na-emekarị nke a na-ahụ na mgbidi cell osisi.A maghị na ọ ga-ebute mmeghachi omume nfụkasị na ọha mmadụ.Agbanyeghị, ndị mmadụ nwere nrịanrịa ama ama ma ọ bụ mmetụta maka ihe ndị sitere na cellulose kwesịrị ịkpachara anya wee kpọtụrụ ndị ọkachamara ahụike tupu ha eri ngwaahịa nwere CMC.
5. Nchekwa digestive: CMC anaghị etinye uche na usoro nri mmadụ ma na-agafe na eriri afọ na-enweghị metabolized.A na-ewere ya dị ka onye na-adịghị egbu egbu na nke na-adịghị ewe iwe na mucosa digestive.Otú ọ dị, ịṅụbiga mmanya ókè nke CMC ma ọ bụ ihe ndị ọzọ na-emepụta cellulose nwere ike ime ka ahụ erughị ala afọ, bloating, ma ọ bụ afọ ọsịsa na ụfọdụ ndị mmadụ.
6. Mmekọrịta na ọgwụ: A maghị CMC ka ya na ọgwụ na-emekọ ihe ma ọ bụ na-emetụta mmịnye ha na tract gastrointestinal.A na-ewere ya na ọ dabara na ọtụtụ usoro ọgwụ, a na-ejikarị ya dị ka ihe na-enye aka n'ụdị usoro onunu dị ka mbadamba, capsules, na nkwusioru.
7. Nchekwa gburugburu ebe obibi: CMC bụ ihe na-emebi emebi na mmekọrịta gburugburu ebe obibi, n'ihi na ọ na-esite na isi mmalite ndị a na-emegharịgharị dị ka osisi pulp ma ọ bụ cellulose owu.Ọ na-akụda ndammana na gburugburu ebe obibi site na microbial omume na ọ dịghị agbakọta na ala ma ọ bụ mmiri usoro.

A na-ahụta sodium carboxymethyl cellulose (CMC) dị ka ọ dị mma maka oriri mgbe ejiri ya dabere na ntuziaka usoro yana ụkpụrụ nchekwa guzobere.A mụọla ya nke ọma maka nsi ya, ihe nfụkasị ahụ, nchekwa nri nri na mmetụta gburugburu ebe obibi, ma kwado ya maka iji ya dị ka ihe mgbakwunye nri na ihe mgbakwunye ọgwụ n'ọtụtụ mba n'ụwa niile.Dị ka ihe oriri ma ọ bụ mgbakwunye ọ bụla, ndị mmadụ n'otu n'otu kwesịrị iri ngwaahịa nwere CMC n'ụzọ kwesịrị ekwesị dị ka akụkụ nke nri ziri ezi ma kpọtụrụ ndị ọkachamara ahụike ma ọ bụrụ na ha nwere mgbochi nri ma ọ bụ nchegbu ahụike.