Hydroxypropylmethylcellulose (HPMC) yog cov khoom siv ntau yam siv hauv ntau qhov kev lag luam, suav nrog cov chaw muag tshuaj thiab kev noj haus.Nws muaj nyob rau hauv cov tshuaj ntxiv tuaj yeem raug ntaus nqi rau ntau yam khoom muaj txiaj ntsig, ua rau nws muaj txiaj ntsig zoo rau cov qauv tsim.
1. Taw qhia rau Hydroxypropyl Methylcellulose (HPMC):
Hydroxypropylmethylcellulose yog ib tug semi-synthetic polymer muab los ntawm cellulose, ib tug natural polymer pom nyob rau hauv cov nroj tsuag cell phab ntsa.Cov synthesis muaj kev kho cellulose nrog propylene oxide thiab methyl chloride, ua rau cov tebchaw nrog cov khoom zoo dua qub piv rau lawv cov niam txiv cellulose.HPMC paub txog nws cov dej solubility, muaj peev xwm ua zaj duab xis, thiab biocompatibility.
2. Cov qauv thiab cov khoom siv tshuaj:
HPMC muaj cov piam thaj rov ua dua tshiab nrog hydroxypropyl thiab methoxy hloov pauv.Qib ntawm kev hloov pauv (DS) yog hais txog qhov nruab nrab ntawm cov neeg hloov pauv hauv ib chav tsev piam thaj thiab tuaj yeem sib txawv, cuam tshuam rau cov khoom ntawm HPMC.Cov pab pawg hydroxypropyl pab txhawb rau cov dej solubility, thaum pab pawg methoxy muab cov khoom ua yeeb yaj kiab.
3. Kev ua haujlwm ntawm cov tshuaj ntxiv:
A. Binders thiab disintegrants:
HPMC ua raws li kev khi thiab pab khi cov khoom xyaw hauv cov ntsiav tshuaj ntxiv ua ke.Nws cov khoom disintegrating pab cov ntsiav tshuaj dissolution, xyuas kom cov ntsiav tshuaj tawg mus rau hauv me me hais kom pom zoo nyob rau hauv lub digestive system.
b.Sustained tso tawm:
Kev tswj kev tso tawm ntawm cov khoom xyaw nquag yog qhov tseem ceeb rau qee cov tshuaj ntxiv.HPMC yog siv los tsim cov matrix uas tswj cov kev tso tawm ntawm cov tshuaj, uas ua rau muaj kev ruaj ntseg thiab tswj cov khoom noj khoom haus ntau dua.
C. Capsule txheej:
Ntxiv nrog rau cov ntawv thov cov ntsiav tshuaj, HPMC kuj tseem siv los ua cov khoom siv rau cov tshuaj ntsiav ntxiv.Cov khoom ua yeeb yaj kiab ntawm HPMC pab txhawb kev txhim kho cov tshuaj ntsiav uas yooj yim rau nqos thiab tawg tau zoo hauv txoj hnyuv.
d.Stabilizers thiab thickeners:
HPMC ua tus stabilizer nyob rau hauv cov kua formulations los tiv thaiv cov Cheebtsam ntawm kev sib cais.Nws lub peev xwm los ua kom cov kev daws teeb meem hauv kev txhim kho cov kua dej khov los yog kev ncua hauv cov kua tshuaj.
e.Vegetarian thiab Vegan Recipes:
HPMC yog muab los ntawm cov nroj tsuag thiab tsim nyog rau cov neeg tsis noj nqaij thiab vegan ntxiv formulations.Qhov no yog nyob rau hauv txoj kab nrog kev loj hlob ntawm cov neeg siv khoom xav tau kev hloov pauv ntawm cov nroj tsuag thiab kev coj ncaj ncees hauv kev tsim khoom.
4. Kev txiav txim siab:
Hydroxypropyl methylcellulose feem ntau lees paub tias muaj kev nyab xeeb (GRAS) los ntawm cov koom haum tswj hwm xws li US Food and Drug Administration (FDA) thiab European Food Safety Authority (EFSA).Nws txoj kev siv dav hauv cov tshuaj thiab cov tshuaj ntxiv tau txais kev txhawb nqa los ntawm nws qhov profile kev nyab xeeb.
5. Cov kev sib tw thiab kev txiav txim siab:
A. Sensitivity rau ib puag ncig tej yam kev mob:
HPMC kev ua tau zoo yuav raug cuam tshuam los ntawm ib puag ncig yam xws li av noo.Cov neeg tsim khoom yuav tsum ua tib zoo xav txog cov xwm txheej khaws cia kom muaj kev ruaj ntseg ntxiv thiab ua haujlwm tau zoo.
b.Kev sib cuam tshuam nrog lwm cov khoom xyaw:
HPMC yuav tsum raug soj ntsuam rau kev sib raug zoo nrog lwm cov khoom xyaw hauv kev tsim kom tsis txhob muaj kev cuam tshuam uas yuav cuam tshuam rau tag nrho cov khoom zoo.
6. Xaus:
Hydroxypropyl methylcellulose plays lub luag haujlwm tseem ceeb hauv kev noj zaub mov ntxiv, pab txhim kho kev ruaj ntseg, bioavailability thiab yooj yim ntawm kev noj ntau yam khoom noj khoom haus.Nws cov khoom siv ntau yam ua rau nws yog qhov kev xaiv zoo tshaj plaws rau cov qauv tsim los txhim kho qhov kev ua tau zoo thiab rov hais dua ntawm lawv cov tshuaj ntxiv.Raws li cov neeg siv khoom nyiam hloov pauv, HPMC yuav zoo li yuav yog qhov tseem ceeb hauv kev txhim kho cov txheej txheem kev noj zaub mov zoo thiab muaj txiaj ntsig zoo.
Post lub sij hawm: Dec-26-2023