ʻO ka Hydroxypropylmethylcellulose (HPMC) kahi mea hoʻohui i hoʻohana ʻia i nā ʻoihana like ʻole me ka lāʻau lapaʻau, ka meaʻai, ke kūkulu ʻana a me nā mea hoʻonaninani.ʻO ka hoʻomaopopo ʻana i kona haku mele ʻana, ka hoʻolālā, nā waiwai a me nā noi e pono ai ke aʻo hohonu ʻana i kāna hana kemika a me ke kaʻina hana synthesis.
haku mele ʻana a me ke ʻano
Cellulose Backbone: Loaʻa ka HPMC mai ka cellulose, he polymer maoli i loaʻa i loko o nā paia o nā mea kanu.Hoʻokumu ʻia ka cellulose me nā kaulahao lōʻihi o nā ʻāpana glucose i hoʻopili pū ʻia e nā paʻa β-1,4 glycosidic.
Methylation: ʻO ka Methylcellulose kahi mea mua i ka HPMC a ua hana ʻia e ka mālama ʻana i ka cellulose me ka alkali a me ka methyl chloride.ʻO ke kaʻina hana e hoʻololi i nā pūʻulu hydroxyl (-OH) ma ka iwi kuamoʻo cellulose me nā pūʻulu methyl (-CH3).
Hydroxypropylation: Ma hope o ka methylation, hiki mai ka hydroxypropylation.Ma kēia ʻanuʻu, hana ka propylene oxide me ka methylated cellulose, e hoʻokomo ana i nā pūʻulu hydroxypropyl (-OCH2CHOHCH3) ma ka iwi kuamoʻo.
Degree of Substitution (DS): ʻO ke degere o ka hoʻololi ʻana e pili ana i ka helu awelika o nā pūʻulu hydroxypropyl a me methyl no kēlā me kēia ʻāpana glucose i ke kaulahao cellulose.Hoʻopili kēia ʻāpana i nā waiwai o HPMC, me kona solubility, viscosity, a me nā ʻano wela.
hoʻohuihui
Lapaʻau alkaline: Hoʻohana mua ʻia nā fiber cellulose me kahi solution alkaline, maʻamau ka sodium hydroxide (NaOH), e wāwahi i nā paʻa hydrogen intermolecular a hoʻonui i ka hiki o nā pūʻulu cellulose hydroxyl.
Methylation: Hoʻopili ʻia ka cellulose i mālama ʻia me ka alkali me ka methyl chloride (CH3Cl) ma lalo o nā kūlana i hoʻomalu ʻia, e hopena i ka hoʻololi ʻana o nā pūʻulu hydroxyl me nā pūʻulu methyl.
Hydroxypropylation: Hoʻopili hou ka methylated cellulose me ka propylene oxide (C3H6O) i mua o kahi mea hoʻoheheʻe e like me ka sodium hydroxide.Hoʻokomo kēia hopena i nā pūʻulu hydroxypropyl i loko o ka iwi kuamoʻo cellulose.
Neutralization a me ka hoʻomaʻemaʻe: Neutralize i ka hoʻohui ʻana e hoʻoneʻe i nā kumu keu.Hoʻomaʻemaʻe ʻia ka huahana i loaʻa e like me ka kānana ʻana, ka holoi ʻana, a me ka maloʻo ʻana no ka loaʻa ʻana o ka huahana HPMC hope loa.
hiʻona
Solubility: Hiki ke hoʻoheheʻe ʻia ka HPMC i ka wai a hoʻokumu ʻia i ka hopena akaka, ʻeleʻele.ʻO ka solubility e pili ana i nā mea e like me ke degere o ka hoʻololi ʻana, ke kaumaha molekala, a me ka mahana.
Viscosity: Hōʻike nā hāʻina HPMC i ke ʻano pseudoplastic, ʻo ia hoʻi, e emi ana ko lākou viscosity me ka piʻi ʻana o ka shear rate.Hiki ke hoʻomalu ʻia ka viscosity e ka hoʻoponopono ʻana i nā ʻāpana e like me DS, paona molekala a me ka ʻike.
Hoʻokumu kiʻiʻoniʻoni: Hana ʻo HPMC i nā kiʻiʻoniʻoni maʻalahi a maopopo ke hoʻolei ʻia mai kāna ʻano wai.Loaʻa kēia mau kiʻiʻoniʻoni i nā noi i loko o ka uhi, ka pahu a me nā lāʻau lapaʻau.
Paʻa Thermal: Paʻa wela ka HPMC i kekahi mahana, ma luna aʻe o ka pōʻino.ʻO ke kūpaʻa wela e pili ana i nā mea e like me DS, ʻoluʻolu ʻoluʻolu, a me ka loaʻa ʻana o nā mea hoʻohui.
Nā wahi noi
Lapaʻau Lapaʻau: Hoʻohana nui ʻia ʻo HPMC i nā ʻano lāʻau lapaʻau e like me nā mānoanoa, nā mea hoʻopili, nā mea hana kiʻiʻoniʻoni a me nā matrices hoʻokuʻu mau.Hoʻomaikaʻi ia i ka disintegration papa, hoʻoheheʻe a me ka bioavailability.
Meaʻai: Ma ka ʻoihana meaʻai, hoʻohana ʻia ʻo HPMC ma ke ʻano he mānoanoa, stabilizer, emulsifier a me ka hoʻopiha piha i nā huahana e like me nā kīʻaha, nā lole, nā mea i kālua ʻia a me nā huahana waiū.
Hana ʻia: Hoʻohui ʻia ʻo HPMC i nā mortar sima, stucco a me nā mea hoʻopili tile e hoʻomaikaʻi ai i ka hana, ka paʻa ʻana o ka wai a me ka pili.Hoʻomaikaʻi ia i ka hana o kēia mau mea kūkulu hale ma nā ʻano kūlana like ʻole.
Mea Hoʻomaʻamaʻa: Hoʻohana ʻia ʻo HPMC ma ke ʻano he mānoanoa, emulsifier a me ka stabilizer i loko o nā mea hoʻonaninani e like me ka ʻaila, nā lotions a me nā gels.Hāʻawi ia i nā waiwai rheological makemake a hoʻonui i ka paʻa o ka huahana.
ʻO ka Hydroxypropyl methylcellulose (HPMC) kahi pūhui multifunctional i hoʻohui ʻia mai cellulose ma o ka methylation a me nā kaʻina hydroxypropylation.ʻO kāna ʻano kemika, nā waiwai a me nā noi e lilo ia i mea waiwai nui i nā ʻoihana like ʻole e like me nā lāʻau lapaʻau, nā meaʻai, ke kūkulu ʻana a me nā mea hoʻonaninani.Ke hoʻomau nei ka noiʻi a me ka hoʻomohala ʻana o ka ʻenehana HPMC i kāna mau noi kūpono a hoʻomaikaʻi i kāna hana ma nā ʻano hana like ʻole.
Ka manawa hoʻouna: Feb-20-2024