Hydroxypropylmethylcellulose (HPMC) isanganiswa uye inoshanda zvakasiyana-siyana ine maapplication akasiyana siyana maindasitiri.Kuti unzwisise hunhu hwayo, munhu anofanirwa kunyura mune izvo zvinosanganisa, maitiro ekugadzira, uye mabviro.
Zvinoumba HPMC:
HPMC ndeye semi-synthetic polymer inotorwa kubva ku cellulose, yakasikwa polysaccharide inowanikwa muchirimwa sero madziro.Nzvimbo huru ye cellulose ihuni pulp kana cotton fiber.Iyo synthesis yeHPMC inosanganisira kushandura cellulose kuburikidza nenhevedzano yemakemikari maitiro kuti iite kubva kune cellulose.
Synthetic maficha ekugadzirwa kweHPMC:
Etherification process:
Kugadzirwa kweHPMC kunosanganisira etherification ye cellulose ine propylene oxide uye methyl chloride.
Munguva iyi, hydroxypropyl uye methyl mapoka anounzwa mu cellulose musana, achigadzira HPMC.
Kugadziriswa kwekemikari:
Kugadziridzwa kwemakemikari kwakaunzwa panguva yekubatanidza kunoita kuti HPMC irondedzerwe semi-synthetic compound.
Degree of substitution (DS) inoreva avhareji yenhamba yehydroxypropyl uye methyl mapoka paglucose unit mucheni ye cellulose.Iyi DS kukosha inogona kugadziriswa panguva yekugadzira maitiro kuti uwane HPMC ine chaiyo zvivakwa.
Kugadzirwa kwemaindasitiri:
HPMC inogadzirwa mumaindasitiri pamwero mukuru nemakambani akati wandei vachishandisa inodzorwa kemikari.
Maitiro ekugadzira anosanganisira chaiwo mamiriro ekuzadzisa zvinodiwa zvivakwa uye kushanda kwechigadzirwa chekupedzisira.
Natural sources yeHPMC:
Cellulose sechisikigo sosi:
Cellulose ndiyo yakakosha zvinhu zveHPMC uye yakawanda muzvisikwa.
Miti, kunyanya huni nedonje, inzvimbo dzakapfuma dze cellulose.Kubviswa kweselulosi kubva kune aya masosi masosi kunotanga iyo HPMC kugadzira maitiro.
Biodegradability:
HPMC inoodza, chivakwa chezvakawanda zvechisikigo zvinhu.
Kuvapo kwechisikigo cellulose muHPMC kunobatsira kune yayo biodegradable zvivakwa, zvichiita kuti ive nehushamwari kwezvakatipoteredza mune mamwe maapplication.
Zvikumbiro zveHPMC:
mushonga:
HPMC inoshandiswa zvakanyanya muindasitiri yemishonga semaajenti ekuputira, mabhainda uye anoramba achiburitsa matrices mukugadzirwa kwehwendefa.Yayo biocompatibility uye inodzorwa kuburitsa zvivakwa inoita kuti ive yekutanga sarudzo yemasitimu ekutumira zvinodhaka.
Indasitiri yekuvaka:
Mukuvaka, HPMC inoshandiswa sechinhu chekuchengetedza mvura, thickener, uye kuseta nguva regulator mune simende-based zvinhu.Basa rayo mukuvandudza kushanda uye kunamatira kwedhaka uye plasters kwakakosha.
indasitiri yezvekudya:
HPMC inoshandiswa seyakakora uye gelling mumiriri muindasitiri yechikafu.
Inowanzoshandiswa muzvigadzirwa zvekudya zvakadai sesosi, soups uye zvinhu zvakabikwa.
cosmetic:
Muzvizora, HPMC inowanikwa mune dzakasiyana siyana zvigadzirwa zvinosanganisira makirimu, lotions, uye gels, ichiita seyakakora, stabilizer, uye emulsifiers.
Industrial applications:
HPMC's versatility inosvika kune akasiyana maindasitiri ekushandisa, kusanganisira pendi yekugadzira, anonamira uye machira ekugadzira.
Regulatory status:
GRAS chimiro:
MuUnited States, HPMC inowanzo zivikanwa seyakachengeteka (GRAS) kune mamwe maapplication muchikafu neUS Food and Drug Administration (FDA).
Zvinodhaka:
HPMC inoshandiswa mumishonga yemishonga inofanirwa kuenderana nemishonga yemishonga yakadai seUnited States Pharmacopeia (USP) uye European Pharmacopoeia (Ph. Eur.).
mukupedzisa:
Muchidimbu, hydroxypropyl methylcellulose (HPMC) ndeye semi-synthetic polymer inotorwa kubva kune yakasikwa cellulose kuburikidza neinodzorwa kemikari gadziriso maitiro.Kunyangwe yakave neshanduko yakakosha yekugadzira, mabviro ayo ari muzviwanikwa zvakaita sehuni pulp uye donje.Iyo yakasarudzika zvivakwa zveHPMC inoita kuti ive yakakosha komisheni inoshandiswa zvakanyanya mumishonga, kuvaka, chikafu, zvekuzora uye akasiyana maindasitiri.Iko kusanganiswa kwechisikigo cellulose uye synthetic shanduko inobatsira mukusiyana kwayo, biodegradability uye kugamuchirwa kwemitemo mundima dzakasiyana.
Nguva yekutumira: Zvita-18-2023