Kodi HPMC ndi yopangidwa kapena yachilengedwe?

Hydroxypropylmethylcellulose (HPMC) ndi yosunthika komanso yosunthika yomwe imagwiritsidwa ntchito m'mafakitale osiyanasiyana.Kuti timvetse tanthauzo lake, munthu ayenera kufufuza zinthu zake, njira zopangira, ndi chiyambi chake.

Zosakaniza za HPMC:
HPMC ndi semi-synthetic polima yochokera ku cellulose, polysaccharide yopezeka m'makoma a cellulose.Gwero lalikulu la cellulose ndi zamkati zamatabwa kapena ulusi wa thonje.Kaphatikizidwe ka HPMC kumakhudzanso kusintha kwa cellulose kudzera muzochita zingapo zamankhwala kuti ikhale yochokera ku cellulose.

Zophatikizika pakupanga kwa HPMC:
Njira ya Etherification:

Kupanga kwa HPMC kumaphatikizapo etherification ya cellulose ndi propylene oxide ndi methyl chloride.
Panthawiyi, magulu a hydroxypropyl ndi methyl amalowetsedwa mumsana wa cellulose, kupanga HPMC.

Kusintha kwa Chemical:

Kusintha kwamankhwala komwe kumayambika panthawi yophatikizika kumapangitsa kuti HPMC ikhale ngati semi-synthetic pawiri.
Degree of substitution (DS) imatanthawuza kuchuluka kwa magulu a hydroxypropyl ndi methyl pagawo la shuga mu tcheni cha cellulose.Mtengo wa DS uwu ukhoza kusinthidwa panthawi yopanga kuti mupeze HPMC yokhala ndi zinthu zinazake.

Kupanga mafakitale:

HPMC amapangidwa m'mafakitale pamlingo waukulu ndi makampani angapo ntchito ankalamulira mankhwala zimachitikira.
Kupanga kumaphatikizapo mikhalidwe yolondola kuti mukwaniritse zomwe mukufuna komanso magwiridwe antchito a chinthu chomaliza.

Magwero achilengedwe a HPMC:
Cellulose ngati gwero lachilengedwe:

Ma cellulose ndiye maziko a HPMC ndipo ndiwochuluka mwachilengedwe.
Zomera, makamaka matabwa ndi thonje, zimakhala ndi ma cellulose ambiri.Kuchotsa cellulose kuchokera kuzinthu zachilengedwezi kumayambitsa njira yopangira HPMC.

Biodegradability:

HPMC ndi biodegradable, katundu wa zinthu zachilengedwe zambiri.
Kukhalapo kwa cellulose yachilengedwe mu HPMC kumathandizira kuti zinthu zake zisawonongeke, ndikupangitsa kuti ikhale yogwirizana ndi chilengedwe pazinthu zina.

Ntchito za HPMC:
mankhwala:

HPMC imagwiritsidwa ntchito kwambiri m'makampani opanga mankhwala ngati zokutira, zomangira ndi matrices omasulidwa mosalekeza pamapangidwe amapiritsi.Ma biocompatibility ake komanso kutulutsidwa koyendetsedwa bwino kumapangitsa kukhala chisankho choyamba pamakina operekera mankhwala.

Makampani omanga:

Pomanga, HPMC imagwiritsidwa ntchito ngati chosungira madzi, chowonjezera, ndikuyika chowongolera nthawi muzinthu zopangidwa ndi simenti.Udindo wake pakuwongolera magwiridwe antchito ndi kumamatira kwa matope ndi pulasitala ndi wofunikira.

makampani azakudya:

HPMC imagwiritsidwa ntchito ngati thickener ndi gelling wothandizira pamakampani azakudya.
Amagwiritsidwa ntchito kwambiri muzakudya monga sosi, soups ndi zinthu zophika.

zodzikongoletsera:

Mu zodzoladzola, HPMC imapezeka muzinthu zosiyanasiyana kuphatikizapo mafuta odzola, mafuta odzola, ndi ma gels, omwe amagwira ntchito ngati thickeners, stabilizers, ndi emulsifiers.

Mapulogalamu a mafakitale:

Kusinthasintha kwa HPMC kumafikira kuzinthu zosiyanasiyana zamafakitale, kuphatikiza kupanga utoto, zomatira ndi kukonza nsalu.

Zowongolera:
GRAS status:

Ku United States, HPMC imadziwika kuti ndi yotetezeka (GRAS) pazakudya zina ndi US Food and Drug Administration (FDA).

Miyezo yamankhwala:

HPMC ntchito mankhwala mankhwala ayenera kutsatira mfundo pharmacopeial monga United States Pharmacopeia (USP) ndi European Pharmacopoeia (Ph. Eur.).

Pomaliza:
Mwachidule, hydroxypropyl methylcellulose (HPMC) ndi semi-synthetic polima yochokera ku cellulose yachilengedwe kudzera munjira yowongolera yosintha mankhwala.Ngakhale idasintha kwambiri popanga, zoyambira zake zili muzinthu zachilengedwe monga zamkati zamatabwa ndi thonje.The katundu wapadera wa HPMC kupanga pawiri wapatali kwambiri ntchito mankhwala, zomangamanga, chakudya, zodzoladzola ndi mafakitale osiyanasiyana.Kuphatikizika kwa cellulose yachilengedwe ndi masinthidwe opangidwa kumathandizira kusinthasintha kwake, kusinthika kwachilengedwe komanso kuvomerezedwa kwamalamulo m'magawo osiyanasiyana.