Hydroxypropyl methylcellulose (HPMC) shi ne Semi-Synthetic, polymer mai narkewa da ruwa wanda aka samu daga cellulose.Ana amfani da shi sosai a masana'antu daban-daban, ciki har da magunguna, abinci, gine-gine, da kayan kwalliya, saboda abubuwan da ya kebantu da su kamar kauri, ɗaure, shirya fina-finai, da daidaitawa.Duk da haka, yana da mahimmanci a lura cewa HPMC ba ta da takamaiman wurin narkewa saboda ba ya aiwatar da tsarin narkewa na gaskiya kamar kayan crystalline.Madadin haka, yana jurewa tsarin lalatawar thermal lokacin zafi.
1. Abubuwan HPMC:
HPMC fari ne zuwa fari mara wari, mai narkewa a cikin ruwa da sauran kaushi da yawa.Kaddarorin sa sun bambanta dangane da dalilai kamar matakin maye gurbin (DS), nauyin kwayoyin halitta, da girman girman barbashi.Gabaɗaya, yana nuna halaye masu zuwa:
Halin da ba na ionic ba: HPMC ba ya ɗaukar kowane cajin lantarki a cikin bayani, yana mai da shi dacewa da kewayon sauran kayan.
Ƙirƙirar fina-finai: HPMC na iya ƙirƙirar fina-finai masu sauƙi, masu sassauƙa lokacin bushewa, waɗanda ke samun aikace-aikace a cikin sutura, fina-finai, da nau'ikan adadin sakin sarrafawa a cikin magunguna.
Wakilin mai kauri: Yana ba da danko ga mafita, yana mai da shi amfani a samfuran abinci, kayan kwalliya, da magunguna.
Hydrophilic: HPMC yana da babban kusanci ga ruwa, wanda ke ba da gudummawa ga haɓakar sa da abubuwan ƙirƙirar fim.
2. Haɗin kai na HPMC:
An haɗe HPMC ta jerin halayen sinadarai da suka haɗa da cellulose, propylene oxide, da methyl chloride.Tsarin ya ƙunshi etherification na cellulose tare da propylene oxide tare da methylation tare da methyl chloride.Ana iya sarrafa matakin maye gurbin (DS) na hydroxypropyl da ƙungiyoyin methoxy don daidaita kaddarorin HPMC da aka samu.
3. Aikace-aikace na HPMC:
Masana'antar harhada magunguna: Ana amfani da HPMC ko'ina azaman mai haɓakawa a cikin samfuran magunguna, gami da allunan, capsules, mafita na ido, da nau'ikan ƙira-saki.
Masana'antar abinci: Ana amfani da ita azaman mai kauri, stabilizer, da emulsifier a cikin kayan abinci kamar miya, miya, ice cream, da kayan burodi.
Masana'antar gine-gine: Ana ƙara HPMC zuwa samfuran tushen siminti don haɓaka iya aiki, riƙe ruwa, da mannewa.Hakanan ana amfani dashi a cikin tile adhesives, turmi, da ma'ana.
Masana'antar kayan shafawa: Ana amfani da HPMC a cikin nau'ikan kayan kwalliya daban-daban kamar su creams, lotions, da shampoos don kauri da kaddarorin sa.
4. Halayen thermal na HPMC:
Kamar yadda aka ambata a baya, HPMC ba ta da takamaiman wurin narkewa saboda yanayin amorphous.Madadin haka, yana fuskantar lalatawar thermal lokacin zafi.Tsarin lalacewa ya haɗa da karya haɗin sinadarai a cikin sarkar polymer, wanda ke haifar da samuwar samfurori masu lalacewa.
Lalacewar zafin jiki na HPMC ya dogara da abubuwa da yawa, gami da nauyin kwayoyin sa, matakin maye, da kasancewar abubuwan ƙari.Yawanci, lalatawar thermal na HPMC yana farawa a kusa da 200 ° C kuma yana ci gaba tare da ƙara yawan zafin jiki.Bayanan martaba na lalacewa na iya bambanta sosai dangane da takamaiman matakin HPMC da ƙimar dumama.
A lokacin lalatawar thermal, HPMC yana jurewa matakai da yawa na lokaci ɗaya, gami da bushewa, cirewa, da lalata ƙungiyoyin aiki.Babban abubuwan da ke rushewa sun haɗa da ruwa, carbon dioxide, carbon monoxide, methanol, da hydrocarbons daban-daban.
5. Dabarun Bincike na thermal don HPMC:
Ana iya nazarin halayen zafi na HPMC ta amfani da dabaru daban-daban na nazari, gami da:
Binciken Thermogravimetric (TGA): TGA yana auna asarar nauyi na samfurin a matsayin aikin zafin jiki, yana ba da bayani game da kwanciyar hankali ta thermal da rugujewar motsi.
Bambance-bambancen calorimetry na dubawa (DSC): DSC tana auna zafin zafi a ciki ko daga cikin samfuri azaman aikin zafin jiki, yana ba da damar siffanta canjin lokaci da abubuwan zafi kamar narkewa da lalacewa.
Fourier-transform infrared spectroscopy (FTIR): FTIR za a iya amfani dashi don saka idanu da canje-canjen sinadarai a cikin HPMC yayin lalatawar thermal ta hanyar nazarin canje-canje a cikin ƙungiyoyi masu aiki da tsarin kwayoyin halitta.
6. Kammalawa:
HPMC wani nau'in polymer ne tare da aikace-aikace da yawa a cikin magunguna, abinci, gini, da kayan kwalliya.Ba kamar kayan kristal ba, HPMC ba ta da takamaiman wurin narkewa amma yana fuskantar lalatawar thermal lokacin mai zafi.Zazzabi na lalacewa ya dogara da dalilai daban-daban kuma yawanci yana farawa a kusa da 200 ° C.Fahimtar yanayin zafi na HPMC yana da mahimmanci don kulawa da dacewa da sarrafa shi a cikin masana'antu daban-daban.
Lokacin aikawa: Maris-09-2024