IHydroxypropyl methylcellulose (HPMC) iyipolymer eguquguqukayo ethola ukusetshenziswa okubanzi ezimbonini ezahlukahlukene ezihlanganisa ezemithi, ukudla, izimonyo, nezokwakha.Enye yezinto zayo eziyingqayizivele yikhono layo lokwenza ama-gel ngaphansi kwezimo ezithile.Ukuqonda izinga lokushisa le-gelation le-HPMC kubalulekile ekwandiseni ukusetshenziswa kwayo ezinhlelweni ezahlukene.
Isingeniso ku-HPMC:
IHydroxypropyl methylcellulose (HPMC) iyi-semi-synthetic, inert, i-viscoelastic polymer etholakala ku-cellulose.Ngokuvamile isetshenziswa njenge-thickener, stabilizer, emulsifier, kanye nefilimu yangaphambili ngenxa yezakhiwo zayo ezinhle kakhulu zokwenza ifilimu kanye nekhono lokuguqula i-rheology yezinhlelo ezinamanzi.I-HPMC iyancibilika emanzini abandayo, futhi i-viscosity yesixazululo sayo incike ezintweni ezifana nesisindo samangqamuzana, izinga lokushintshwa, kanye nokugxila.
I-Gelation Mechanism:
I-Gelation ibhekisela kunqubo lapho isixazululo sishintsha sibe ijeli, ebonisa ukuziphatha okuqinile okunamandla okugcina isimo saso.Esimeni se-HPMC, ukugeleza kwe-gelation ngokuvamile kwenzeka ngenqubo ebangelwa ukushisa noma ngokungezwa kwamanye ama-agent afana nosawoti.
Izinto ezithinta i-Gelation:
Ukugxiliswa kwe-HPMC: Ukugxila okuphezulu kwe-HPMC ngokuvamile kuholela ekujikeni okusheshayo ngenxa yokwanda kokuxhumana kwe-polymer-polymer.
Isisindo samangqamuzana: Isisindo samangqamuzana esiphezulu se-HPMC ama-polymers ajwayele ukwakha ama-gel kalula ngenxa yokwanda kokubopha kanye nokusebenzisana kwama-intermolecular.
I-Degree of Substitution: Izinga lokushintsha, elibonisa izinga le-hydroxypropyl ne-methyl esikhundleni somgogodla we-cellulose, lithinta izinga lokushisa le-gelation.Amazinga aphezulu okushintsha angehlisa izinga lokushisa le-gelation.
Ukuba khona Kosawoti: Amanye ama-salts, afana ne-alkali metal chloride, angakhuthaza i-gelation ngokusebenzisana namaketanga e-polymer.
Izinga lokushisa: Izinga lokushisa lidlala indima ebalulekile ekwenzeni i-gelation.Njengoba izinga lokushisa likhuphuka, amaketanga e-polymer athola amandla e-kinetic, okwenza kube lula ukuhlela kabusha kwamangqamuzana okudingekile ekwakhekeni kwejeli.
I-Gelation Temperature ye-HPMC:
Izinga lokushisa le-gelation le-HPMC lingahluka kuye ngezinto ezimbalwa okukhulunywe ngazo ngaphambili.Ngokuvamile, amajeli e-HPMC emazingeni okushisa angaphezu kwamazinga okushisa e-gelation, ngokuvamile asukela ku-50°C kuya ku-90°C.Kodwa-ke, lobu bubanzi bungahluka kakhulu ngokuya ngebanga elithile le-HPMC, ukugxila kwayo, isisindo samangqamuzana, nezinye izici zokubunjwa.
Izicelo ze-HPMC Gels:
Ezemithi: Amajeli e-HPMC asetshenziswa kakhulu ekwenziweni kwemithi yokukhishwa kwezidakamizwa okulawulwayo, ukusetshenziswa kwezihloko, kanye nanjengezishintshi ze-viscosity kumafomu omthamo owuketshezi.
Imboni Yokudla: Embonini yokudla, amajeli e-HPMC asetshenziswa njengama-thieners, stabilizer, nama-gelling agents emikhiqizweni eyahlukene njengamasoso, ama-dessert, nemikhiqizo yobisi.
Ukwakhiwa: Amajeli e-HPMC athola ukusetshenziswa ezintweni zokwakha ezifana nodaka lukasimende, lapho asebenza khona njengama-ejenti okugcina amanzi, athuthukisa ukusebenza nokunamathela.
Izimonyo: Amajeli e-HPMC ahlanganiswa ekwenziweni kwezimonyo njengamafutha okhilimu, izinto zokuthambisa, kanye nemikhiqizo yokunakekelwa kwezinwele ngenxa yezakhiwo zazo zokujiya nokuzinzisa.
izinga lokushisa le-gelation le-HPMC lincike ezintweni ezihlukahlukene ezihlanganisa ukugxila, isisindo samangqamuzana, izinga lokushintshwa, kanye nokuba khona kwezithasiselo ezifana nosawoti.Nakuba izinga lokushisa le-gelation ngokuvamile liwela phakathi kwebanga lika-50°C kuya ku-90°C, lingahluka kakhulu ngokuya ngezidingo ezithile zokwakheka.Ukuqonda ukuziphatha kwe-gelation kwe-HPMC kubalulekile ekusetshenzisweni kwayo ngempumelelo kuzo zonke izinhlelo zokusebenza ezihlukene embonini yezemithi, yokudla, yokwakha, nezimonyo.Ucwaningo olwengeziwe mayelana nezici ezithonya i-HPMC gelation lungaholela ekwakhiweni kokwakheka okuthuthukisiwe kanye nezinhlelo zokusebenza ezinoveli zale polymer esebenza ngezindlela eziningi.
Isikhathi sokuthumela: Mar-28-2024