Hydroxypropylmethylcellulose (HPMC) o se polymer multifunctional e maua mai le cellulose lea e faʻaaogaina lautele i pisinisi eseese ona o ona uiga tulaga ese.O le tuufaatasiga o loʻo tuʻufaʻatasia e ala i se faʻasologa o suiga o vailaʻau i le cellulose, o se polymer masani o loʻo maua i totonu o puipui o laau.
mea mata:
Punavai: Cellulose o le mea autu autu o le HPMC, lea e tele i le natura ma maua mai laau.O le pulupulu fafie ma le cotton liters o puna masani ia o le cellulose.
Tu'uesea: O le fa'agasologa o le su'ega e aofia ai le talepeina o puipui sela o la'au ma tu'u'ese'ese ai alava cellulose.E mafai ona fa'aogaina auala fa'apitoa ma masini mo lea fa'amoemoe.
Propylene oxide:
Punavai: O le propylene oxide ose fa'aputuga fa'aola e maua mai i puna'oa fa'ama'i.
Galuega: O le propylene oxide o loʻo faʻaaogaina e faʻafeiloaʻi ai vaega hydroxypropyl i molelaʻau cellulose i le faagasologa o le synthesis, faʻaleleia le solubility o le vai ma suia ai mea faitino o le HPMC e maua.
Methyl chloride:
Punavai: Methyl chloride ose chlorinated hydrocarbon e mafai ona fa'apipi'iina mai le methanol.
Galuega: Methyl chloride o loʻo faʻaaogaina e faʻafeiloaʻi ai vaega methyl i molelaʻau cellulose, lea e saofagā i le hydrophobicity atoa o le HPMC.
Sodium hydroxide (NaOH):
Punavai: Sodium hydroxide, e ta'ua foi o le soda, ose faavae malosi ma e maua i pisinisi.
Galuega: NaOH e faʻaaogaina e faʻapipiʻi ai le tali ma fetuutuunai le tau o le pH o le faʻafefiloi o tali i le taimi o le faʻasologa.
Fa'asologa:
O le tu'ufa'atasiga o le HPMC e aofia ai le tele o la'asaga, ma e mafai ona aoteleina le fa'asologa o le tali e fa'apea:
Alkalizing:
Ole cellulose e togafitia ile sodium hydroxide e maua ai le cellulose alkaline.
Ole cellulose ole alkali ona fa'afo'i lea ile propylene oxide e fa'ailoa ai vaega ole hydroxypropyl.
Methylation:
O le cellulose hydroxypropylated o loʻo faʻaalia atili i le methyl chloride e faʻafeiloaʻi ai vaega methyl.
O lenei laasaga e maua ai le polymer faʻaopoopo le mautu ma le hydrophobicity.
Fa'amama ma fa'amama:
O le fa'afefiloiga tali na fa'a'au'au e aveese ai le fa'avae tele.
Sa faia le fa'amama e fa'aesea ai le cellulose ua suia.
Fufulu ma fa'agogo:
O le oloa tu'ueseese e fufuluina ona fa'agogo lea ina ia maua ai le hydroxypropyl methylcellulose i totonu o le paʻu poʻo le faʻapipiʻi.
Solubility uiga ole HPMC:
HPMC e soluble vai ma e mafai ona fetuutuunai lona solubility e tusa ai ma le tikeri o le suia o hydroxypropyl ma methyl vaega.
Ata fau ata:
O le HPMC o lo'o fa'atūina ata fe'avea'i ma manino e talafeagai mo fa'aoga i fale talavai ma mea'ai.
Viscosity:
O le viscosity o le HPMC solution e mafai ona pulea ma e masani ona faʻaaogaina e avea o se mafiafia ma gelling agent i faʻasologa eseese.
Fa'avela vevela:
O nisi vasega o le HPMC o lo'o fa'aalia ai mea e fa'afefeteina, e fai ai se gel pe a vevela ma toe fo'i i se vaifofo pe a mālūlū.
Gaoioiga i luga:
E mafai ona fa'aogaina le HPMC e fai ma mea fa'afefete, ma o lona gaioiga i luga e a'afia i le maualuga o le sui.
Fa'aaogā vaila'au a le HPMC:
O le HPMC o loʻo faʻaaogaina lautele i vailaʻau faʻamaʻi e pei o fusi, faʻamaʻi, ma faʻamalo faʻasaʻo i totonu o laupepa ma capsules.
Alamanuia faufale:
I le vaega faufale, o le HPMC o loʻo faʻaaogaina e avea o se mafiafia i oloa faʻavae sima e pei o sima ma faʻapipiʻi tile.
alamanuia taumafa:
O lo'o fa'aaogaina le HPMC i le alamanuia o mea'ai e pei o se mafiafia, emulsifier ma fa'amautu i oloa eseese, e aofia ai sosi, suamalie ma aisakulimi.
oloa tau tausiga a le tagata lava ia:
I mea teuteu ma mea e tausia ai le tagata lava ia, e fa'aaogaina le HPMC i fa'aputuga pei o kulimi, lotion ma shampoos ona o lona mafiafia ma fa'amautu mea.
Vali ma Fa'alava:
Ua fa'aopoopoina le HPMC i vali ma fa'alavalava e fa'atonutonu ai le viscosity, fa'aleleia mea fa'aoga ma fa'aleleia mea e fai ai ata.
Fofo ole Mata:
O le HPMC e fa'aaogaina i mata'u mata ma loimata fa'apitoa ona o lona biocompatibility ma mucoadhesive meatotino.
i le faaiuga:
O le Hydroxypropylmethylcellulose (HPMC) o se polymer mata'ina na tuufaatasia mai le cellulose punaoa fa'afouina.O lona tele o mea fa'apitoa ma le tele o fa'aoga o lo'o avea ai ma mea taua i pisinisi eseese, mai vaila'au i le fausiaina ma mea'ai.E ala i le filifilia ma le faaeteete o mea mataʻutia ma le faʻatonutonuina o faʻasologa o faʻasologa, HPMCs faʻatasi ai ma meatotino faʻapitoa e mafai ona gaosia e faʻafetaui manaoga faʻapitoa o talosaga eseese.A'o fa'aauau pea le fa'atupuina o tekonolosi ma mana'oga, e foliga mai e tumau pea le HPMC ose tagata ta'a'alo i le fa'afouga ma le gafataulimaina o le atina'eina o oloa i totonu o alamanuia.
Taimi meli: Tes-18-2023