Hydroxypropylmethylcellulose (HPMC) bụ polymer multifunctional ewepụtara na cellulose nke a na-ejikarị na ụlọ ọrụ dị iche iche n'ihi njirimara pụrụ iche ya.A na-emepụta ngwakọta ahụ site na usoro mgbanwe kemịkalụ na cellulose, polymer eke dị na mgbidi cell osisi.
akụrụngwa:
Isi mmalite: Cellulose bụ isi akụrụngwa nke HPMC, nke dị ukwuu n'okike ma na-amịpụta na osisi.Mkpụrụ osisi na akwa owu bụ isi mmalite nke cellulose.
Mwepu: Usoro mmịpụta na-agụnye ịkwatu mgbidi cell osisi na ikewapụ eriri cellulose.Enwere ike iji usoro kemịkalụ dị iche iche na igwe maka nke a.
Propylene oxide:
Isi mmalite: Propylene oxide bụ ngwakọta organic sitere na isi mmalite nke petrochemical.
Arụ ọrụ: A na-eji propylene oxide ewebata ìgwè hydroxypropyl n'ime mkpụrụ ndụ cellulose n'oge usoro nhazi, na-eme ka mmiri na-edozi mmiri ma na-agbanwe ihe anụ ahụ nke HPMC na-akpata.
Methyl chloride:
Isi mmalite: Methyl chloride bụ hydrocarbon chlorinated nke enwere ike ịme ya site na methanol.
Ọrụ: A na-eji Methyl chloride ewebata otu methyl n'ime mkpụrụ ndụ cellulose, nke na-enye aka na mkpokọta hydrophobicity nke HPMC.
Sodium hydroxide (NaOH):
Isi mmalite: Sodium hydroxide, nke a makwaara dị ka soda caustic, bụ ntọala siri ike ma dị na ahịa.
Arụ ọrụ: A na-eji NaOH mee ka mmeghachi omume na-eme ka mmeghachi omume na-emegharị ma gbanwee uru pH nke ngwakọta mmeghachi omume n'oge usoro nhazi.
Synthesis:
Ngwakọta nke HPMC gụnyere ọtụtụ usoro, na atụmatụ mmeghachi omume nwere ike ichikota dị ka ndị a:
Alkalizing:
A na-eji sodium hydroxide agwọ cellulose iji mepụta cellulose alkaline.
A na-eji propylene oxide meghachi omume Alkali cellulose iji webata otu hydroxypropyl.
Methylation:
Hydroxypropylated cellulose na-emeghachi omume na methyl chloride iji webata otu methyl.
Nzọụkwụ a na-enye polymer ọzọ nkwụsi ike na hydrophobicity.
Nnọpụiche na nzacha:
Ngwakọta mmeghachi omume na-apụ apụ iji wepụ oke isi.
Emere nzacha iji kewapụ cellulose gbanwetụrụ.
Ịsacha na ihicha:
A na-asa ngwaahịa ahụ kewapụrụ wee kpoo ya iji nweta hydroxypropyl methylcellulose na ntụ ntụ ma ọ bụ ụdị granular.
Njirimara solubility nke HPMC:
HPMC bụ mmiri-soluble na ya solubility nwere ike gbanwee dị ka ogo nke nnọchi nke hydroxypropyl na methyl otu.
Ikike imepụta ihe nkiri:
HPMC na-emepụta ihe nkiri na-agbanwe agbanwe, nke na-egosi ihe dabara adaba maka ngwa na ụlọ ọrụ ọgwụ na nri.
Viscosity:
The viscosity nke HPMC ngwọta nwere ike ịchịkwa na-ejikarị dị ka a thickener na gelling gị n'ụlọnga dị iche iche formulations.
Thermal gelation:
Ụfọdụ akara ule HPMC na-egosipụta ihe ọkụ ọkụ, na-akpụ gel mgbe ọ dị ọkụ na ịlaghachi na ngwọta mgbe jụrụ oyi.
Ọrụ elu:
Enwere ike iji HPMC mee ihe dị ka surfactant, ogo nke nnọchi na-emetụta ọrụ elu ya.
Ọgwụ HPMC etinyere:
A na-eji HPMC eme ihe n'ụdị usoro ọgwụ dị ka ndị na-ekekọta, ndị na-ekesa, na ihe ntọhapụ a na-achịkwa na mbadamba na capsules.
Ụlọ ọrụ ihe owuwu:
N'ebe a na-ewu ihe owuwu, a na-eji HPMC eme ihe dị ka ihe na-esi ísì ụtọ na ngwaahịa simenti dị ka ngwa agha na nrapado tile.
ụlọ ọrụ nri:
A na-eji HPMC eme ihe na ụlọ ọrụ nri dị ka ihe na-eku ume, emulsifier na stabilizer na ngwaahịa dị iche iche, gụnyere sauces, desserts na ice cream.
Ngwaahịa nlekọta onwe onye:
N'ihe ịchọ mma na ngwaahịa nlekọta onwe onye, a na-eji HPMC mee ihe n'ụdị dị ka ude, lotions na shampoos n'ihi ihe na-eme ka ọ sie ike na nkwụsi ike.
Agba na mkpuchi:
A na-agbakwunye HPMC na agba na mkpuchi iji chịkwaa viscosity, melite ngwa ngwa ma kwalite ihe ndị na-emepụta ihe nkiri.
Ngwọta anya:
A na-eji HPMC eme ihe na anya mmiri na anya mmiri arụrụ arụ n'ihi na ọ na-ekwekọghị na ya na mucoadhesive Njirimara.
na ngwụcha:
Hydroxypropylmethylcellulose (HPMC) bụ polymer dị ịrịba ama emepụtara site na cellulose akụ nwere ike imeghari.Ngwongwo ya multifunctional na ngwa dịgasị iche iche na-eme ka ọ bụrụ isi ihe dị na ụlọ ọrụ dị iche iche, site na ọgwụ na-ewu ụlọ na nri.Site na nhọpụta nke ngwa ngwa na njikwa nke paramita njikọ, HPMC nwere ihe ndị ahaziri iche nwere ike mepụta iji gboo mkpa dị iche iche nke ngwa dị iche iche.Ka teknụzụ na mkpa na-aga n'ihu na-etolite, HPMC nwere ike ịnọgide na-abụ isi ihe na-emepụta ihe ọhụrụ na mmepe ngwaahịa na-adigide n'ofe ụlọ ọrụ.
Oge nzipu: Dec-18-2023