Klasifikasi dumasar rute administrasi
1. Tablet (tablet coated, tablet matrix, tablet multi-layer), pil, kapsul (capsules enteric-coated, capsules résin ubar, capsules coated) jsb dikaluarkeun ngaliwatan saluran cerna.
2. Parenteral administrasi injections, suppositories, film, implants, jsb.
Numutkeun kana téknik préparasi anu béda-béda, préparasi pelepasan anu tahan tiasa dibagi kana:
1. Rorongkong-dispersed sustained-release olahan ①Water-leyur matrix, carboxymethylcellulose (CMC), hydroxypropylmethylcellulose (HPMC), polyvinylpyrrolidone (PVP), jsb ilahar dipaké salaku bahan matrix;②Matriks larut lemak, Zat lemak sareng lilin biasana dianggo salaku bahan rangka;③ rorongkong leyur, plastik non-toksik leyur ilahar dipaké salaku bahan rangka.
2. Mémbran-dikawasa sustained-release olahan ilaharna ngawengku film-coated sustained-release olahan jeung sustained-release microcapsules.Tujuan ngadalikeun laju release ubar mindeng kahontal ku ngadalikeun ketebalan kapsul, diaméter micropores, sarta curvature tina micropores.
3. Sustained-release emulsions Ubar larut cai bisa dijieun kana W / O emulsions, sabab minyak miboga éfék panghalang tangtu dina difusi molekul ubar pikeun ngahontal tujuan release sustained.
4. Sustained-release olahan pikeun suntik dijieun tina leyuran minyak jeung suntik gantung.
5. Olahan pilem sustained-release mangrupakeun olahan pilem sustained-release dijieun ku encapsulating ubar dina compartments pilem polimér, atawa ngabubarkeun na dispersing aranjeunna dina lambar pilem polimér.
waktos pos: Apr-17-2023