Ethylcellulose e tsoa ho selulose, polima ea tlhaho e entsoeng ka likarolo tsa tsoekere.E entsoe ka ho arabela selulose ka ethyl chloride kapa ethylene oxide, ho hlahisa limolek'hule tsa cellulose tse nkeloang sebaka.Ethylcellulose e na le lisebelisoa tse ngata tsa lik'hemik'hale tse e etsang hore e sebelisoe mefuteng e fapaneng ea liindasteri le litlhare.
Sebopeho sa Molek'hule:
Ethylcellulose e boloka sebopeho sa motheo sa selulose, se nang le likarolo tse pheta-phetoang tsa tsoekere tse kopantsoeng ka li-bond β-1,4-glycosidic.
Phapanyetsano ea Ethyl e etsahala haholo-holo lihlopheng tsa hydroxyl tsa mokokotlo oa selulose, e leng se bakang likhato tse fapaneng tsa substitution (DS) e bonts'ang palo e tloaelehileng ea lihlopha tsa ethyl ho unit ea glucose.
Tekanyo ea ho nkela sebaka e ama thepa ea ethylcellulose, ho kenyelletsa le solubility, viscosity, le bokhoni ba ho etsa filimi.
Sollubility:
Ka lebaka la tlhaho ea hydrophobic ea sehlopha sa ethyl, ethylcellulose ha e qhibilihe ka metsing.
E bonts'a ho qhibiliha mefuteng e fapaneng ea li-solvents, ho kenyelletsa le joala, li-ketone, li-ester le li-hydrocarbon tse chlorinated.
Solubility e eketseha ka ho fokotseha ha boima ba limolek'hule le ho eketseha ha tekanyo ea ethoxylation.
Litšobotsi tsa ho etsa lifilimi:
Ethylcellulose e tsejoa ka bokhoni ba eona ba ho etsa lifilimi, e leng se etsang hore e be ea bohlokoa tlhahisong ea liphahlo, lifilimi le mekhoa ea meriana e laoloang.
Bokhoni ba ethylcellulose ho qhibiliha ka mefuta e sa tšoaneng ea li-solvents bo khothalletsa ho thehoa ha filimi, 'me ka mor'a moo mouoane oa motsoako o siea filimi e tšoanang.
Reactivity:
Ethylcellulose e bonts'a reactivity e batlang e le tlase tlas'a maemo a tloaelehileng.Leha ho le joalo, e ka fetoloa ka lik'hemik'hale ka liketso tse kang etherification, esterification, le cross-linking.
Boitšoaro ba Etherification bo kenyelletsa ho hlahisoa ha lintho tse ling tse ling mokokotlong oa cellulose, ka hona ho fetola thepa.
Esterification e ka etsahala ka ho arabela ethylcellulose ka carboxylic acid kapa acid chloride, ho hlahisa li-cellulose ester tse nang le ho qhibiliha ho fetotsoeng le lintho tse ling.
Liphetoho tse amanang le sefapano li ka qalisoa ho ntlafatsa matla a mochine le botsitso ba mocheso oa li-membrane tsa ethyl cellulose.
Tšebetso ea mocheso:
Ethylcellulose e bontša botsitso ba mocheso ka har'a mocheso o itseng oa mocheso, ho feta moo ho senyeha ho hlahang.
Ho senyeha ha mocheso hangata ho qala ho pota 200-250 ° C, ho itšetlehile ka lintlha tse kang tekanyo ea ho nkela sebaka le boteng ba li-plasticizers kapa li-additives.
Tlhahlobo ea Thermogravimetric (TGA) le differential scanning calorimetry (DSC) ke mekhoa e sebelisoang hangata ho khetholla boitšoaro ba mocheso oa ethylcellulose le metsoako ea eona.
lumellana:
Ethylcellulose e lumellana le mefuta e mengata ea li-polymers, li-plasticizers le li-additives, e leng se etsang hore e loketse ho kopanya le lisebelisoa tse ling ho finyella thepa e lakatsehang.
Li-additives tse tloaelehileng li kenyelletsa li-plasticizers tse kang polyethylene glycol (PEG) le triethyl citrate, tse matlafatsang ho feto-fetoha ha maemo le thepa ea ho etsa lifilimi.
Ho lumellana le metsoako e sebetsang ea meriana (APIs) ho bohlokoa ha ho etsoa liforomo tsa litekanyetso tsa meriana tse kang matlapa a ho lokolloa ka nako e telele le li-patches tsa transdermal.
Tšebetso ea mokoallo:
Lifilimi tsa Ethylcellulose li bonts'a thepa e ntle ea thibelo khahlano le mongobo, likhase le mouoane oa manyolo.
Lintho tsena tse thibelang li etsa hore ethylcellulose e tšoanelehe bakeng sa lits'ebetso tsa ho paka moo ts'ireletso ho tsoa linthong tsa tikoloho e leng bohlokoa ho boloka botšepehi ba sehlahisoa le bophelo ba sethala.
Lintho tsa Rheological:
Viscosity ea tharollo ea ethylcellulose e itšetlehile ka lintlha tse kang polymer concentration, degree of substitution, le mofuta oa solvent.
Litharollo tsa Ethylcellulose hangata li bonts'a boits'oaro ba pseudoplastic, ho bolelang hore viscosity ea bona e fokotseha ka sekhahla sa ho kuta.
Lithuto tsa ramatiki li bohlokoa ho utloisisa litšobotsi tsa phallo ea tharollo ea ethylcellulose nakong ea ts'ebetso le likopo tsa ho roala.
Ethylcellulose ke polymer e feto-fetohang e nang le mefuta e mengata ea lik'hemik'hale e kenyang letsoho molemong oa eona lits'ebetsong tse fapaneng tsa indasteri le tsa meriana.Ho qhibiliha ha eona, bokhoni ba ho etsa lifilimi, ho sebetsa hape, botsitso ba mocheso, ho lumellana, thepa ea thibelo le rheology e etsa hore e be thepa ea bohlokoa bakeng sa ho roala, lifilimi, mekhoa e laoloang ea tokollo le tharollo ea liphutheloana.Lipatlisiso le nts'etsopele e eketsehileng lefapheng la lihlahisoa tsa cellulose li ntse li tsoela pele ho atolosa lisebelisoa le bokhoni ba ethylcellulose likarolong tse sa tšoaneng.
Nako ea poso: Feb-18-2024