Hydroxypropylcellulose (HEC) e tsoa ho cellulose, polymer ea tlhaho e fumanehang maboteng a lisele tsa semela.HPC e sebelisoa haholo liindastering tse fapaneng tse kang tsa meriana, litlolo le liindasteri tsa lijo ka lebaka la thepa ea eona e ntle ea ho etsa lifilimi le ho tenya.Tlhahiso ea hydroxypropylcellulose e kenyelletsa mehato e mengata mme ts'ebetso e ka ba e rarahaneng.
Selelekela sa hydroxypropylcellulose:
1. Ho sebelisa cellulose e le lisebelisoa tsa ho qala:
Mehloli e ka sehloohong ea selulose ke lisebelisoa tsa semela tse kang makhasi a lehong kapa k'hothone.Cellulose ke polymer e nang le linear e entsoeng ka likaroloana tsa tsoekere tse hokahantsoeng ke libonto tsa β-1,4-glycosidic.E na le boemo bo phahameng ba polymerization, ka likete tsa likarolo tsa tsoekere tse etsang liketane tse telele.
2. Maikutlo a Etherification:
Tšimoloho ea hydroxypropylcellulose e kenyelletsa ho kenngoa ha lihlopha tsa hydroxypropyl mokokotlong oa cellulose ka etherification.Karabelo ena hangata e kenyelletsa tšebeliso ea propylene oxide e le alkylating agent.
Cellulose + propylene oxide → alkali-catalyzed hydroxypropyl cellulose + by-product cellulose + propylene oxide alkali-catalyzed hydroxypropyl cellulose + by-product
Base catalysis e bohlokoa ho khothaletsa karabelo lipakeng tsa lihlopha tsa cellulose hydroxyl le propylene oxide.Hangata mohato ona o etsoa tlas'a maemo a laoloang ho netefatsa tekanyo e lakatsehang ea ho fetola (DS) ea lihlopha tsa hydroxypropyl ka ketane ea cellulose.
3. Hydroxypropylation:
Hydroxypropylation e kenyelletsa ho kenyelletsoa ha lihlopha tsa hydroxypropyl mokokotlong oa cellulose.Phetoho ena e fana ka ho qhibiliha ho ntlafalitsoeng le lisebelisoa tse ling tse lakatsehang ho cellulosic polymer.Maemo a ho itšoara, ho kenyelletsa mocheso, khatello le nako ea ho itšoara, li laoloa ka hloko ho finyella thepa e lakatsehang ea sehlahisoa.
4. Kalafo ea alkali:
Ka mor'a hydroxypropylation, phekolo ea alkaline hangata e sebelisoa ho fokotsa litšila leha e le life tse setseng tsa asiti le ho fetola pH ea motsoako oa karabelo.Mohato ona ke oa bohlokoa bakeng sa ts'ebetso e latelang ea tlhoekiso.
5. Mehato ea tlhoekiso:
Kamora karabelo ea etherification, mehato e 'maloa ea tlhoekiso hangata e etsoa ho fumana hydroxypropylcellulose e phahameng.Mehato ena e ka kenyelletsa:
Hlatsoa: Hlatsoa motsoako oa karabelo ho tlosa li-reagents tse setseng, lihlahisoa le selulose e sa sebetsanoang.
Filtration: Filtration e sebelisoa ho arola litšila tse tiileng le motsoako oa karabelo.
Ho omisa: Selulose e metsi ea hydroxypropyl e ntan'o omisoa ho tlosa mongobo ofe kapa ofe o setseng.
6. Taolo ea boima ba limolek'hule:
Boima ba limolek'hule tsa hydroxypropylcellulose bo ka laoloa nakong ea synthesis ho etsa hore thepa ea eona e lumellane le lits'ebetso tse ikhethileng.Sena se finyelloa ka ho lokisa maemo a karabelo, joalo ka bongata ba li-reagents le nako ea karabelo.
Tlhahiso ea indasteri:
1. Ts'ebetso ea nakoana kapa e tsoelang pele:
Tlhahiso ea selulose ea hydroxypropyl e ka etsoa ka batch kapa mekhoa e tsoelang pele.Ts'ebetso ea li-batch e loketse tlhahiso e nyenyane, ha ts'ebetso e tsoelang pele e loketse haholoanyane bakeng sa tlhahiso e kholo.
2. Taolo ea boleng:
Mehato ea taolo ea boleng e kengoa ts'ebetsong mekhahlelong eohle ea ts'ebetso ea tlhahiso ho netefatsa botsitso le bohloeki ba sehlahisoa sa ho qetela.Mekhoa ea ho hlahloba e kang chromatography, spectroscopy le lithuto tsa rheological li sebelisoa ho hlahloba lintlha tsa bohlokoa tse kang tekanyo ea ho fetola, boima ba limolek'hule le bohloeki.
Lisebelisoa tsa Hydroxypropyl Cellulose:
1. Indasteri ea meriana:
Hydroxypropylcellulose e sebelisoa haholo litokisetsong tsa meriana e le ntho e tlamang, e senyang le e laoloang ea tokollo.Ho lumellana ha eona le mefuta e mengata ea lithethefatsi le ho se sebetse ha eona ho etsa hore e be mothusi ea fapaneng.
2. Indasteri ea litlolo:
Ka indasteri ea litlolo, hydroxypropylcellulose e sebelisoa ha ho etsoa lihlahisoa tsa tlhokomelo ea moriri, litlolo tsa letlalo le lihlahisoa tse ling tsa tlhokomelo ea motho.Lintho tsa eona tsa ho etsa lifilimi li etsa hore e be ea bohlokoa lihlahisoa tsa tlhokomelo ea moriri.
3. Indasteri ea lijo:
Indastering ea lijo, hydroxypropylcellulose e sebelisoa e le ntho e teteaneng le ea gelling.E fumanoa lijong tse sa tšoaneng 'me e thusa ho ntlafatsa sebopeho sa bona le botsitso.
Tšimoloho ea hydroxypropylcellulose e kenyelletsa etherification ea selulose ka ho eketsoa ha lihlopha tsa hydroxypropyl.Karabelo hangata e hlahisoa ke motheo, e lateloa ke mehato ea tlhoekiso ho fumana sehlahisoa se hloekileng haholo.Tlhahiso ea indasteri e ka etsoa ka batch kapa mekhoa e tsoelang pele ka mehato e tiileng ea ho laola boleng.Hydroxypropylcellulose e na le mefuta e mengata ea lisebelisoa indastering ea meriana, ea litlolo le ea lijo ka lebaka la thepa ea eona e ikhethang le ho feto-fetoha ha maemo.Ntlafatso e tsoelang pele ea lits'ebetso tsa tlhahiso le nts'etsopele ea lits'ebetso tse ncha li totobatsa
Nako ea poso: Dec-26-2023