HPMC ya Mankhwala

Mtengo wa HPMCza mankhwalachakhala chimodzi mwa zazikulu kuchuluka kwachisamaliro chaumoyo ndiexcipients mankhwala kunyumba ndi kunja, chifukwa HPMC mankhwala ali ubwino kuti excipients ena alibe.

1. Kusungunuka kwamadzi

HPMC mankhwala ndi sungunuka m'madzi ozizira m'munsimu 40 ℃ kapena 70% Mowa.Sipasungunuke m'madzi otentha kuposa 60 ℃, koma imatha kusungunuka.

2. Chemical inertia

HPMC mankhwala ndi sanali ionic mapadi efa, yankho alibe ayoni mlandu ndi zitsulo mchere kapena ayoni organic mankhwala, kotero pokonzekera ndondomeko kupanga, excipients ena sachita nazo.

3. Kukhazikika

Ndiwokhazikika kwa onse asidi ndi maziko, ndipo akhoza kusungidwa mu osiyanasiyana PH 3 ~ 11 kwa nthawi yaitali popanda kusintha koonekeratu mamasukidwe akayendedwe.HPMC amadzimadzi yothetsera ali kukana mildew ndipo akhoza kusunga kukhuthala kukhazikika bwino kukhazikika posungira nthawi yaitali.Zothandiza pamankhwala pogwiritsa ntchito HPMC pamankhwala, kukhazikika kwake kwabwino kuposa kugwiritsa ntchito zopangira zachikhalidwe (monga dextrin, wowuma, ndi zina) ndizabwinoko.

4. Kusintha mamasukidwe akayendedwe

HPMC zotumphukira zosiyanasiyana mamasukidwe akayendedwe akhoza zikugwirizana malinga ndi kufanana zosiyanasiyana, mamasukidwe akayendedwe ake akhoza kusintha malinga ndi malamulo ena, ndipo ali ndi ubale wabwino liniya, kotero izo zikhoza kusankhidwa malinga ndi zosowa za chiŵerengero.2. 5 kagayidwe kachakudya inertia HPMC si odzipereka mu thupi si zimapukusidwa, sapereka kutentha, choncho ndi otetezeka mankhwala kukonzekera excipients..

5. Chitetezo

Mtengo wa HPMCza mankhwalanthawi zambiri amatengedwa kuti si zinthu zoopsa komanso zosakhumudwitsa.

Hydroxypropyl methyl cellulose (HPMC).celluloseether opangidwa ndi zomwe chloromethane ndi propylene oxide ndi cellulose yoyambira.Ulusi woyera kapena pafupifupi woyera kapena ufa wonyezimira, wopanda fungo.Lakhala likugwiritsidwa ntchito m'makampani opanga mankhwala kwa zaka zopitilira 40, ndipo lakhazikitsidwa mu USP19 edition ndi Chinese Pharmacopoeia 1990 edition.Zakhala ndi zotsatira zabwino pazitsulo zokutira mafilimu ndi ntchito zomatira.

Gulu la mankhwalaMtengo wa HPMChydroxypropyl methyl cellulose ali ndi zofunika kwambiri pa zopangira, luso kupanga ndi khalidwe mankhwala.M'zaka zaposachedwa, mothandizidwa ndi malamulo okhwima oteteza zachilengedwe, mabizinesi ena ang'onoang'ono othandizira mankhwala ku East China asiya msika, komanso kalasi yamankhwala.Mtengo wa HPMChydroxypropyl methyl celluloseza mankhwalamafakitale akhudzidwanso, ntchito zina zazing'ono zazing'ono zatha, ndipo kuchuluka kwa mphamvu kwasinthidwa.