Hydroxypropyl methylcellulose (HPMC) bụ polymer vasatail eji na ụlọ ọrụ dị iche iche n'ihi ihe pụrụ iche ya.Ọ bụ ezie na enwere ike iji ya mepụta hydrogels n'okpuru ọnọdụ ụfọdụ, ọ bụghị hydrogel n'onwe ya.
1. Okwu mmalite nke HPMC:
Hydroxypropyl methylcellulose (HPMC) bụ polymer synthetic ọkara nke sitere na cellulose, polymer eke dị na mgbidi cell nke osisi.A na-emepụta ya site n'ịgwọ cellulose na alkali wee meghachi ya na propylene oxide na methyl chloride.Polymer na-esi na ya pụta na-egosiputa ihe dị iche iche na-eme ka ọ baa uru na ụlọ ọrụ dị iche iche, gụnyere ọgwụ, nri, ihe ịchọ mma, na ihe owuwu.
2. Njirimara nke HPMC:
HPMC nwere ọtụtụ uru bara uru:
a.Ngwọta mmiri:
HPMC bụ soluble na mmiri, na-akpụ a viscous ngwọta.Ngwongwo a bara uru karịsịa na ọgwụ, ebe enwere ike iji ya mepụta nkwusioru, emulsions, na njikwa-ntọhapụ ọgwụ.
b.Ikike imepụta ihe nkiri:
HPMC nwere ike ịmepụta ihe nkiri na-agbanwe agbanwe na nke doro anya mgbe a na-etinye ya na ngwọta mmiri.Ihe nkiri ndị a na-achọta ngwa na mkpuchi maka mbadamba nkume, capsules, na ihe nkiri ọnụ.
c.Mgbanwe Rheology:
HPMC na-arụ ọrụ dị ka thickener na rheology modifier na aqueous ngwọta.Enwere ike ịhazi viscosity ya site n'ịgbanwe ihe ndị dị ka ịdị arọ molekụla na ogo nke nnọchi.
d.Nkwekọrịta ihe ndị dị ndụ:
HPMC bụ ihe dakọtara na ya anaghị egbu egbu, na-eme ka ọ dabara adaba maka iji ọgwụ, ihe ịchọ mma na ngwaahịa nri.
3. Ngwa nke HPMC:
HPMC na-achọta ngwa zuru ebe niile n'ofe ụlọ ọrụ dị iche iche:
a.Ngwa ahịa ọgwụ:
N'ime usoro ọgwụ, a na-eji HPMC dị ka ihe nchikota, ihe na-agbasa, ihe mkpuchi ihe nkiri, yana matriks ntọhapụ na-akwadobu.Ọ na-akwalite iguzosi ike n'ezi ihe nke mbadamba ihe, na-achịkwa kanetics ntọhapụ ọgwụ, ma na-akwalite nnabata ndị ọrịa.
b.Ụlọ ọrụ nri:
N'ụlọ ọrụ nri, HPMC na-arụ ọrụ dị ka onye na-ebu ibu, emulsifier, stabilizer, na onye na-ahụ maka gelling.Ọ na-enye aka na nhazi, viscosity, na nkwụsi ike nke ngwaahịa nri dị ka sauces, uwe, na desserts.
c.Ihe ịchọ mma:
A na-eji HPMC eme ihe ịchọ mma na ngwaahịa nlekọta onwe onye dị ka onye na-agba agba, onye na-akwụsịtụ, ihe nkiri mbụ, na emulsifier.Ọ na-enye ihe ndị a na-achọsi ike na ude, lotions, na gels ka ha na-eme ka nkwụsi ike na àgwà ha dịkwuo mma.
d.Ihe owuwu:
N'ime ụlọ ọrụ ihe owuwu, a na-eji HPMC n'ihe simenti dị ka ihe na-ejigide mmiri, ihe na-arụ ọrụ na-arụ ọrụ, na ihe na-emekọ ihe.Ọ na-eme ka ngwa ngwa na njirimara plasta dịkwuo mma, dị ka nrapagide, njikọta, na nguzogide sag.
4. Hydrogel Formation na HPMC:
Ọ bụ ezie na HPMC n'onwe ya abụghị hydrogel, ọ nwere ike itinye aka na nhazi hydrogel n'okpuru ọnọdụ kwesịrị ekwesị.Hydrogel bụ netwọk nke ụdọ polymer nke nwere ike ịmịkọrọ na idowe nnukwu mmiri.Nhazi nke HPMC hydrogels na-agụnyekarị ịgafe ụdọ polymer iji mepụta netwọk nwere akụkụ atọ nwere ike ịmị mmiri.
a.Ndị nnọchi anya crosslink:
Enwere ike iji ihe ndị na-emekọrịta ihe dị ka glutaraldehyde, genipin, ma ọ bụ ụzọ anụ ahụ dị ka cycles friza-thaw ga-arụ ọrụ iji jikọta ụdọ HPMC.Njikọ njikọ a na-ebute nguzobe nke netwọk hydrogel n'ime matrix HPMC.
b.Àgwà Ọzịza:
Enwere ike ịhazi akụrụngwa hydrogel nke HPMC site na ịhazigharị ihe ndị dị ka ogo nke nnọchi, ịdị arọ molecular, na njupụta njikọ.Ngosipụta dị elu nke nnọchi na ịdị arọ molekụla n'ozuzu na-eduga n'ịbawanye ike ọzịza hydrogel.
c.Ngwa nke HPMC Hydrogels:
HPMC hydrogels na-achọta ngwa na nnyefe ọgwụ, ọgwụgwọ ọnya, injin anụ ahụ, na anya anya kọntaktị.Ngwongwo biocompatibility ha, ihe a na-emegharị emegharị, na ike idowe mmiri na-eme ka ha dabara maka ngwa biomedical dị iche iche.
HPMC bụ polymer bara ụba nwere ngwa dị iche iche n'ofe ọgwụ, nri, ihe ịchọ mma, na ụlọ ọrụ ihe owuwu.Ọ bụ ezie na ọ bụghị hydrogel, ọ nwere ike isonye na nhazi hydrogel site na ijikọta ụdọ polymer ya.Ihe si na HPMC hydrogels na-egosipụta akụrụngwa dị ka nnabata mmiri na njide, na-eme ka ha baa uru na ngwa biomedical.Ka nyocha na-aga n'ihu na-enyocha ojiji na usoro nke HPMC, mkpa ya na ụlọ ọrụ dị iche iche ga-abawanye ụba.
Oge nzipu: Mar-06-2024