Capsule Qib HPMC rau Pharma Daim Ntawv Thov

Hydroxypropyl methylcellulose (HPMC) yog ntau yam polymer uas tau siv dav hauv kev lag luam tshuaj vim nws cov khoom tshwj xeeb xws li solubility siab, biocompatibility, thiab tsis muaj tshuaj lom.Capsule qib HPMC, tseem hu ua hypromellose, tshwj xeeb yog tsim los siv rau hauv cov tshuaj capsule plhaub.Hauv tsab xov xwm no, peb yuav tham txog cov khoom, kev tsim khoom, thiab kev siv tshuaj ntsiav qib HPMC.

Cov khoom ntawm Capsule Qib HPMC

Capsule qib HPMC yog semi-synthetic, inert, thiab dej-soluble polymer muab los ntawm cellulose.Nws yog cov hmoov dawb rau cov hmoov dawb uas tsis muaj ntxhiab, tsis qab, thiab tsis muaj dej.Cov khoom tseem ceeb ntawm qib HPMC capsule yog:

Siab solubility: Capsule qib HPMC dissolves nkag hauv dej thiab tsim cov kev daws teeb meem.Nws muaj qhov kub thiab txias, uas txhais tau hais tias nws tuaj yeem tsim cov gels ntawm qhov kub thiab txias.

Non-toxicity: Capsule qib HPMC yog cov tshuaj tsis muaj tshuaj lom neeg uas muaj kev nyab xeeb rau tib neeg noj.Nws kuj tau pom zoo los ntawm ntau lub koom haum tswj hwm xws li US FDA, European Pharmacopoeia, thiab Japanese Pharmacopoeia.

Biocompatibility: Capsule qib HPMC yog sib xws nrog cov kab mob lom thiab tsis ua rau muaj kev phom sij rau tib neeg kev noj qab haus huv.

pH stability: Capsule qib HPMC ruaj khov nyob rau hauv ntau yam ntawm pH qhov tseem ceeb, uas ua rau nws haum rau siv nyob rau hauv acidic, nruab nrab, thiab yooj yim ib puag ncig.

Cov khoom ua yeeb yaj kiab: Capsule qib HPMC tuaj yeem tsim cov yeeb yaj kiab muaj zog thiab hloov tau yooj yim uas tiv taus tawg, tev, thiab tawg.

Tswj-tso cov khoom: Capsule qib HPMC tuaj yeem siv los tswj kev tso tawm cov tshuaj los ntawm lub plhaub capsule, uas ua rau nws muaj txiaj ntsig zoo rau kev tsim cov tshuaj txuas ntxiv.

Kev tsim cov Capsule Qib HPMC

Capsule qib HPMC yog tsim los ntawm chemically modifying natural cellulose nrog propylene oxide thiab methyl chloride.Qib ntawm kev hloov pauv (DS) ntawm HPMC nyob ntawm qhov piv ntawm propylene oxide rau methyl chloride siv hauv cov tshuaj tiv thaiv.Tus nqi DS qhia txog pes tsawg pawg hydroxyl ntawm cov cellulose uas tau hloov nrog hydroxypropyl thiab methyl pawg.

Capsule qib HPMC muaj nyob rau hauv ntau qib, nyob ntawm nws cov viscosity thiab qib hloov pauv.Lub viscosity ntawm HPMC yog qhov ntsuas ntawm nws qhov hnyav molecular thiab qib ntawm polymerization.Qhov siab dua qhov viscosity, siab dua qhov hnyav molecular thiab thicker cov tshuaj.Qhov degree ntawm kev hloov pauv txiav txim siab txog kev solubility thiab gelation ntawm HPMC.

Kev siv Capsule Qib HPMC

Capsule qib HPMC yog dav siv nyob rau hauv kev lag luam kws tshuaj rau kev tsim cov capsule plhaub.Capsule shells yog siv los encapsulate cov tshuaj yeeb tshuaj thiab muab txoj hauv kev yooj yim thiab nyab xeeb ntawm kev xa tshuaj rau cov neeg mob.Cov ntawv thov tseem ceeb ntawm qib HPMC qib capsule hauv kev lag luam kws tshuaj yog:

Cov neeg tsis noj nqaij: Capsule qib HPMC yog ib qho kev xaiv nrov rau gelatin capsules, uas yog muab los ntawm cov tsiaj txhu.Cov neeg tsis noj nqaij cov tshuaj ntsiav ua los ntawm HPMC yog tsim rau siv nyob rau hauv vegan thiab neeg tsis noj nqaij formulations thiab muaj ib tug tsis muaj noo noo cov ntsiab lus, uas ua rau lawv ruaj khov thiab yooj yim mus lis.

Cov tshuaj tiv thaiv-tso tawm: Capsule qib HPMC tuaj yeem siv los tswj kev tso tshuaj tawm ntawm lub plhaub capsule.Tus nqi ntawm cov tshuaj tso tawm tuaj yeem tswj tau los ntawm kev kho cov viscosity thiab qib ntawm kev hloov pauv ntawm HPMC.Qhov no ua rau cov tshuaj capsule qib HPMC muaj txiaj ntsig zoo rau kev tsim cov ntawv tso tawm txuas ntxiv uas tuaj yeem muab cov tshuaj xa mus rau lub sijhawm.

Enteric-coated capsules: Capsule qib HPMC tuaj yeem siv los ua cov tshuaj enteric-coated capsules, uas yog tsim los tso cov tshuaj hauv cov hnyuv es lub plab.Enteric-coated capsules muaj txiaj ntsig zoo rau cov tshuaj uas nkag siab rau qhov acidic ib puag ncig ntawm lub plab lossis ua rau khaus rau hauv plab.

Saj-masking: Capsule qib HPMC tuaj yeem siv los npog qhov iab saj ntawm cov tshuaj uas muaj qhov tsis zoo.HPMC tuaj yeem siv los tsim cov xim pleev xim rau ntawm cov khoom siv tshuaj, uas tuaj yeem txhim kho cov neeg mob ua raws cai thiab kev lees paub.

Solubility li qub: Capsule qib HPMC tuaj yeem txhim kho cov solubility ntawm cov tshuaj tsis zoo soluble los ntawm kev tsim cov khoom tawg.HPMC tuaj yeem siv los pleev xim rau cov khoom siv tshuaj thiab txhim kho lawv cov khoom ntub dej thiab kev sib cais.

Excipient: Capsule qib HPMC tuaj yeem siv los ua cov khoom siv hauv ntau hom tshuaj xws li ntsiav tshuaj, tshuaj pleev, thiab tshuaj ncua.Nws tuaj yeem ua raws li kev sib khi, disintegrant, emulsifier, thiab stabilizer, nyob ntawm cov qauv tsim.

Xaus

Capsule qib HPMC yog ntau yam thiab dav siv polymer hauv kev lag luam tshuaj.Nws muaj cov khoom tshwj xeeb xws li solubility siab, tsis muaj tshuaj lom, thiab biocompatibility, uas ua rau nws yog ib qho khoom siv rau kev siv hauv capsule shells.Cov txheej txheem tsim khoom ntawm qib capsule HPMC suav nrog kev hloov kho cov cellulose ntuj nrog propylene oxide thiab methyl chloride kom tau txais qhov xav tau viscosity thiab qib kev hloov pauv.Capsule qib HPMC pom ntau yam kev siv hauv kev lag luam kws tshuaj, xws li hauv kev tsim cov neeg tsis noj nqaij capsules, tswj-tso formulations, enteric-coated capsules, saj-masking, solubility li, thiab raws li ib tug excipient nyob rau hauv ntau yam formulations.