IHydroxypropyl Methylcellulose (HPMC) iyi-polymer esetshenziswa kakhulu ezimbonini ezahlukahlukene, kufaka phakathi ezemithi, ukudla, izimonyo, nezokwakha.Esinye sezici ezibalulekile zokusetshenziswa kwayo ukuncibilika kwayo, ikakhulukazi emanzini abandayo.Lesi sihloko sidingida ekuziphatheni kokuncibilika kwe-HPMC emanzini abandayo, ihlola izici zayo, izici ezithonya ukunyibilika, izindlela zokuthuthukisa ukunyibilika, kanye nezinhlelo zokusebenza.
IHydroxypropyl Methylcellulose (HPMC) iyi-polymer etholakala ku-cellulose.Isetshenziswa kakhulu ezimbonini ezahlukahlukene ngenxa yezakhiwo zayo ezihlukile, okuhlanganisa ukujiya, ukubopha, ukwenza ifilimu, namandla okugcina amanzi.Esinye sezici ezibalulekile ezithonya ukusebenza kwayo ukuncibilika kwayo, ikakhulukazi emanzini abandayo.Ukuqonda ukuziphatha kokuncibilika kwe-HPMC emanzini abandayo kubalulekile ekwandiseni ukusetshenziswa kwayo emikhakheni ehlukene.
1.Izakhiwo ze-HPMC
I-HPMC ibonisa izakhiwo ze-amphiphilic ngenxa yokuba khona kwamaqembu e-hydrophobic methyl kanye namaqembu e-hydrophilic hydroxypropyl.Le mvelo ye-amphiphilic ivumela i-HPMC ukuthi ihlanganyele nama-molecule wamanzi futhi yakhe izixazululo ezizinzile.Ukunyibilika kwe-HPMC kuncike ezintweni ezimbalwa, okuhlanganisa isisindo samangqamuzana, izinga lokushintshwa, kanye nezinga lokushisa.
2.Ukuncibilika kwe-HPMC emanzini Abandayo
I-HPMC ibonisa ukuncibilika okulinganiselwe emanzini abandayo uma kuqhathaniswa namanzi ashisayo.Ukunyibilika kwe-HPMC emanzini abandayo kuthonywa izici ezifana nezinga lokushintsha, isisindo samangqamuzana, usayizi wezinhlayiyana, kanye nokuba khona kwezinye izinyibilikisi.Ngokuvamile, isisindo esiphansi samangqamuzana kanye nezinga eliphakeme lokuthatha indawo lithuthukisa ukunyibilika kwe-HPMC emanzini abandayo.
3.Izici Ezithonya Ukunyibilika
Kunezici ezimbalwa ezithinta ukunyibilika kwe-HPMC emanzini abandayo, okuhlanganisa:
Isisindo samangqamuzana: Isisindo samangqamuzana aphansi I-HPMC ijwayele ukuncibilika kalula emanzini abandayo ngenxa yokwanda kokuhamba kwamaketanga.
I-Degree of Substitution: Amazinga aphezulu okushintshanisa e-hydroxypropyl namaqembu e-methoxy athuthukisa ukunyibilika kwe-HPMC ngokwandisa i-hydrophilicity.
Usayizi Wezinhlayiyana: Usayizi wezinhlayiyana ezincane usiza ukuqedwa ngokushesha kwe-HPMC emanzini abandayo.
Izinga lokushisa: Amanzi abandayo anciphisa amandla e-kinetic wama-molecule, awenza angasebenzi kahle ekwephuleni amabhondi e-intermolecular, ngaleyo ndlela ehlisa ukunyibilika kwe-HPMC.
4.Izindlela Zokuthuthukisa Ukunyibilika
Izindlela ezahlukahlukene zingathuthukisa ukuncibilika kwe-HPMC emanzini abandayo, kufaka phakathi:
I-Pre-hydration: Ukucwiliswa ngaphambili kwe-HPMC emanzini abandayo ngaphambi kokuyengeza ekubunjweni kungathuthukisa ukuhlakazeka nokuncibilika kwayo.
Ukunciphisa Usayizi Wezinhlayiya: Ukugaywa noma ukwenziwa kwezinhlayiyana ze-HPMC ezincane kungakhuphula indawo yazo, kukhuthaze ukuqedwa ngokushesha.
Ukuguqulwa Kwekhemikhali: Ukushintsha ukwakheka kwamakhemikhali e-HPMC ngokusebenzisa kokuphuma kokunye kungathuthukisa ukunyibilika kwayo emanzini abandayo.
Ama-Solubilizers: Ukwengezwa kwama-ejenti a-solubilizing njengama-surfactants noma izincibilikisi ezihlangene kungathuthukisa ukunyibilika kwe-HPMC emanzini abandayo.
5.Izicelo ze-HPMC emanzini Abandayo
Naphezu kokuncibilika kwayo okulinganiselwe emanzini abandayo, i-HPMC ithola izinhlelo zokusebenza ezihlukahlukene ekwenziweni okudinga ukuhlakazeka kwamanzi abandayo.Ezinye izinhlelo zokusebenza ezijwayelekile zifaka:
Ukwakhiwa Kwemithi: I-HPMC isetshenziswa ezingxenyeni zamathebulethi, ekwenziweni kokukhishwa okuqhubekayo, kanye namaphilisi ahlakazekayo ngomlomo adinga ukuncibilika kwamanzi abandayo ukuze kusetshenziswe.
Imboni Yokudla: I-HPMC isetshenziswa emikhiqizweni yokudla efana neziphuzo ezisheshayo, izinto zokubhaka, kanye nemikhiqizo yobisi ngenxa yezakhiwo zayo zokujiya kanye ne-gelling emanzini abandayo.
Izimonyo: I-HPMC ifakwe ekwenziweni kwezimonyo okufana nokhilimu, izinto zokuthambisa, namajeli adinga ukuhlakazeka kwamanzi abandayo ukuze kube lula ukusetshenziswa.
Ukwakhiwa: Ezintweni zokwakha ezifana nodaka, ama-grouts, nama-cementitious coatings, i-HPMC isetshenziswa njenge-ejenti egcina amanzi, edinga ukunyibilika kwamanzi abandayo ukuze kuhlakazwe kahle.
Sengiphetha, ukunyibilika kwe-HPMC emanzini abandayo kudlala indima ebalulekile ekusetshenzisweni kwayo kuzo zonke izimboni ezihlukahlukene.Ngenkathi i-HPMC ibonisa ukunyibilika okulinganiselwe emanzini abandayo uma kuqhathaniswa namanzi ashisayo, izakhiwo zayo zingathuthukiswa ngezici ezifana nesisindo samangqamuzana, izinga lokushintsha, nosayizi wezinhlayiyana.Ukuqonda izici ezithonya ukunyibilika kwe-HPMC emanzini abandayo kubalulekile ekwakhekeni kwemikhiqizo esebenzayo kanye nokuthuthukisa ukusebenza kwayo ezinhlelweni ezihlukene.
Isikhathi sokuthumela: Apr-03-2024