Ukwenziwa kwejeli ye-Hydroxyethyl cellulose

I-Hydroxyethyl cellulose (HEC) yipolymer engeyiyo i-ionic yamanzi enyibilikayo esetyenziswa kakhulu kumashishini ahlukeneyo ngenxa yokuqina kwayo, ukubopha kunye nokuzinzisa iipropati.Ngokukodwa, i-HEC idla ngokusetyenziswa ekuqulunqweni kweegels, ezizii-semi-solid okanye izinto eziqinileyo ezine-jelly-like consistency kwaye ziyakwazi ukubamba ubuninzi be-liquid.Kule nqaku, siza kuhlolisisa ukuqulunqwa kwe-gel ye-hydroxyethyl cellulose kunye nezinto ezinokuchaphazela iimpawu zayo.

Ukuqulunqwa kwejeli ye-hydroxyethyl cellulose kubandakanya amacandelo amaninzi abalulekileyo, kuquka i-HEC, i-solvent, kunye nezinye izongezo njengoko zifuneka.Esinye isinyibilikisi esiqhelekileyo esisetyenziswa kwi-HEC i-gel formulations ngamanzi, ngokuqhelekileyo asetyenziselwa ukunyibilikisa i-polymer ye-HEC kunye nokudala ijeli.Nangona kunjalo, ezinye izinyibilikisi ezifana ne-glycerin, i-propylene glycol, kunye ne-ethanol nazo zingasetyenziselwa ukuguqula iipropati zejeli.

Ukongeza kwi-solvent, izongezo ezahlukahlukeneyo zingabandakanywa kwi-gel formulation ye-hydroxyethyl cellulose ukulungelelanisa iimpawu zayo.Ngokomzekelo, i-preservatives inokongezwa ukukhusela ukukhula kwebhaktheriya kunye nokwandisa ubomi beshelufu ye-gel, ngelixa i-surfactants ingasetyenziselwa ukunceda i-emulsify i-gel kunye nokuphucula ukuhambelana kwayo.Ezinye izongezo eziqhelekileyo ziquka i-humectants, enceda ukugcina ukufuma kwijeli, kunye ne-colorants okanye iziqhumiso zokuphucula ukubonakala kwayo kunye nevumba.

Enye into ebalulekileyo ekufuneka iqwalaselwe ekuqulunqweni kwejeli ye-hydroxyethyl cellulose yi-viscosity efunwayo okanye ubukhulu bemveliso yokugqibela.I-viscosity ye-gel inqunywe ngokuxinwa kwe-polymer ye-HEC, kunye nomlinganiselo we-solvent kwi-polymer.Ukugxininiswa okuphezulu kwe-HEC kunye ne-solvent-to-polymer ratios ephantsi kuya kubangela i-gel eninzi, i-viscous.Ukukhethwa kwe-solvent kunokuchaphazela i-viscosity ye-gel, kunye ne-solvents ethile evelisa i-gel ene-thicker or thin consistency.

Enye into ekufuneka iqwalaselwe ekuqulunqweni kwejeli ye-hydroxyethyl cellulose kukucaca kwejeli okanye ukungafihli.I-HEC i-gels inoluhlu olucacileyo kunye nokungafihli ukuya kwi-opaque kunye ne-milky, kuxhomekeke ekubunjweni kunye nokongezwa kwamanye amacandelo.Ukusetyenziswa kwe-solvents okanye izongezo ezithile kunokuchaphazela ukucaca kwe-gel, kwaye amabakala athile e-HEC anokuba ngaphezulu okanye ngaphantsi kwe-opaque kuxhomekeke kubunzima be-molecular kunye neqondo lokutshintshwa.

Enye into enokubakho ekuqulunqweni kweegels ze-hydroxyethyl cellulose kukuzinza kwazo ngokuhamba kwexesha.Kwezinye iimeko, iigel ze-HEC zinokuthi zilungele i-syneresis, oku kukwahlulwa kolwelo olusuka kwijeli ngenxa yokutshintsha kweqondo lobushushu okanye ezinye izinto.Ukujongana nalo mbandela, i-stabilizers kunye ne-thickeners ezifana ne-xanthan gum okanye i-carrageenan inokongezwa ekuqulunqweni kokuphucula ukuzinza kwe-gel kunye nokukhusela i-syneresis.

Ukuqukumbela, ukuqulunqwa kwejeli ye-hydroxyethyl cellulose kubandakanya ibhalansi ecokisekileyo yamacandelo ahlukeneyo kunye nezinto, kubandakanywa nokukhethwa kwe-solvent, ukuxinwa kwe-polymer ye-HEC, kunye nokongezwa kwezongezo ezahlukahlukeneyo zokulungelelanisa iipropati ze-gel.Ngokulawula ngokucophelela ezi ziguquko, kunokwenzeka ukwenza i-gel ye-hydroxyethyl cellulose kunye ne-viscosity efunwayo, ukucaca, kunye nokuzinza, enokusetyenziswa kwizicelo ezininzi, ukusuka kwimveliso yokunyamekela komntu ukuya kwiingubo zoshishino kunye ne-adhesives.