Hydroxyethyl cellulose gel formulation

Hydroxyethyl cellulose (HEC) yog non-ionic dej-soluble polymer uas yog dav siv nyob rau hauv ntau yam lag luam vim nws thickening, khi, thiab stabilizing zog.Tshwj xeeb, HEC feem ntau siv rau hauv kev tsim cov gels, uas yog cov khoom ib nrab lossis cov khoom siv uas muaj cov jelly zoo li sib xws thiab muaj peev xwm tuav tau cov kua ntau.Hauv tsab xov xwm no, peb yuav tshawb nrhiav cov qauv ntawm hydroxyethyl cellulose gel thiab cov yam ntxwv uas tuaj yeem cuam tshuam rau nws cov khoom.

Lub formulation ntawm hydroxyethyl cellulose gel muaj ntau yam tseem ceeb, xws li HEC, hnyav, thiab lwm yam additives raws li xav tau.Ib qho hnyav hnyav uas siv hauv HEC gel formulations yog dej, uas feem ntau yog siv los yaj cov HEC polymer thiab tsim cov gel.Txawm li cas los xij, lwm cov kuab tshuaj xws li glycerin, propylene glycol, thiab ethanol kuj tuaj yeem siv los hloov kho cov khoom ntawm cov gel.

Ntxiv rau qhov hnyav, ntau yam khoom ntxiv tuaj yeem suav nrog hauv hydroxyethyl cellulose gel formulation los kho nws cov khoom.Piv txwv li, cov tshuaj tua kab mob tuaj yeem raug ntxiv los tiv thaiv kab mob kev loj hlob thiab txuas ntxiv lub neej ntawm cov gel, thaum surfactants tuaj yeem siv los pab emulsify cov gel thiab txhim kho nws qhov sib xws.Lwm cov tshuaj ntxiv muaj xws li humectants, uas pab khaws cov dej noo hauv cov gel, thiab cov xim los yog cov tshuaj tsw qab los txhim kho nws cov tsos thiab tsw.

Ib qho tseem ceeb uas yuav tsum tau xav txog hauv kev tsim cov hydroxyethyl cellulose gel yog qhov xav tau viscosity lossis tuab ntawm cov khoom kawg.Lub viscosity ntawm gel yog txiav txim siab los ntawm qhov concentration ntawm HEC polymer, nrog rau qhov sib piv ntawm hnyav rau polymer.Qhov siab dua ntawm HEC thiab qis dua cov kuab tshuaj-rau-polymer piv yuav ua rau cov kua nplaum tuab dua, cov kua nplaum ntau dua.Kev xaiv cov kuab tshuaj kuj tuaj yeem cuam tshuam qhov viscosity ntawm cov gel, nrog qee cov kuab tshuaj ua cov gels nrog cov thicker lossis thinner sib xws.

Lwm qhov tseem ceeb uas yuav tsum xav txog hauv kev tsim cov hydroxyethyl cellulose gel yog gel qhov pom tseeb lossis opacity.HEC gels tuaj yeem ua tau los ntawm cov ntshiab thiab pob tshab mus rau opaque thiab milky, nyob ntawm kev tsim thiab sib ntxiv ntawm lwm cov khoom.Kev siv qee cov kuab tshuaj los yog cov tshuaj ntxiv tuaj yeem cuam tshuam rau cov pob tshab ntawm cov gel, thiab qee qib ntawm HEC yuav ntau dua lossis tsawg dua opaque nyob ntawm lawv qhov hnyav molecular thiab qib hloov pauv.

Ib qho teeb meem muaj peev xwm hauv kev tsim cov hydroxyethyl cellulose gels yog lawv cov kev ruaj ntseg nyob rau lub sijhawm.Qee zaum, HEC gels tuaj yeem ua rau muaj kev sib koom ua ke, uas yog kev sib cais ntawm cov kua dej los ntawm cov gel vim qhov hloov pauv ntawm qhov kub thiab txias lossis lwm yam.Txhawm rau daws qhov teeb meem no, stabilizers thiab thickeners xws li xanthan cov pos hniav lossis carrageenan tuaj yeem muab ntxiv rau hauv cov qauv los txhim kho kev ruaj ntseg ntawm cov gel thiab tiv thaiv syneresis.

Nyob rau hauv xaus, lub formulation ntawm hydroxyethyl cellulose gel muaj ib tug ceev faj tshuav nyiaj li cas ntawm ntau yam Cheebtsam thiab yam, nrog rau cov kev xaiv ntawm hnyav, lub concentration ntawm HEC polymer, thiab ntxiv rau ntau yam additives los kho cov gel lub zog.Los ntawm kev ua tib zoo tswj cov kev hloov pauv no, nws muaj peev xwm tsim tau hydroxyethyl cellulose gel nrog qhov xav tau viscosity, clarity, thiab ruaj khov, uas tuaj yeem siv rau ntau yam kev siv, los ntawm cov khoom tu tus kheej mus rau cov txheej txheem thiab cov nplaum.