Hydroxypropyl methyl cellulose (HPMC) ke polymer e feto-fetohang e sebelisoang haholo liindastering tse fapaneng, ho kenyeletsoa lijo, meriana le kaho.Ke semi-synthetic derivative ea cellulose, e leng polima ea tlhaho e fumanehang maboteng a lisele tsa semela.HPMC e entsoe ka ho fetola selulose ka lik'hemik'hale ka hydroxypropyl le lihlopha tsa methyl, tse ntlafatsang ho qhibiliha ha metsi, viscosity le lisebelisoa tse ling.Sehloohong sena, re tla tšohla thepa ea HPMC le lits'ebetso tsa eona liindastering tse fapaneng.

Ho qhibiliha ha Metsi

E 'ngoe ea thepa ea bohlokoa ka ho fetisisa ea HPMC ke ho qhibiliha ha eona ha metsi.HPMC e qhibiliha habonolo ka metsing ho etsa tharollo e hlakileng, ea viscous.Tekanyo ea ho qhibiliha e itšetlehile ka tekanyo ea ho fetola (DS) ea HPMC.DS e bolela palo ea lihlopha tsa hydroxypropyl le methyl tse kenyelletsoang molek'hule e 'ngoe le e 'ngoe ea cellulose.Ha DS e phahame, HPMC e tla qhibiliha haholoanyane metsing.HPMC e nang le DS ea 1.8 kapa ho feta e nkuoa e qhibiliha haholo metsing.

Viscosity

Thepa e 'ngoe ea bohlokoa ea HPMC ke viscosity ea eona.HPMC ke polima e nang le viscous haholo, e bolelang hore e na le botenya, bo tsitsitseng.The viscosity ea HPMC itšetlehile ka lintlha tse 'maloa, ho akarelletsa le DS, boima ba molek'hule, le mahloriso a polymer ka tharollo.DS e phahameng le boima ba limolek'hule li baka viscosity e phahameng.Viscosity ea HPMC e ka fetoloa ka ho fapanyetsana mahloriso a polymer ka tharollo.

Thermal Stability

HPMC e tsitsitse ka mocheso mme e ka mamella mocheso ho fihla ho 200 ° C ntle le ho senyeha ho hoholo.Sena se etsa hore e loketse ho sebelisoa lits'ebetsong tse ngata tsa indasteri tse kenyelletsang mocheso o phahameng, joalo ka ho omisa ka spray le extrusion.HPMC e boetse e na le khanyetso e ntle ea li-acids le metheo, e etsang hore e loketse ho sebelisoa libakeng tse nang le asiti kapa alkaline.

Litšobotsi tsa ho Etsa Lifilimi

HPMC e na le thepa e ntle haholo ea ho etsa lifilimi, e etsang hore e be molemo lits'ebetsong tse fapaneng.HPMC e ka etsa filimi e matla, e tenyetsehang e hanyetsanang le mongobo, mocheso le lik'hemik'hale.Sena se etsa hore e be molemo indastering ea meriana bakeng sa ho roala matlapa le li-capsules ho ntlafatsa ponahalo ea bona le botsitso.HPMC e ka boela ea sebelisoa indastering ea lijo ho etsa lifilimi tse jeoang tse ka sebelisoang ho boloka le ho sireletsa lihlahisoa tsa lijo.

Thepa ea Sekhomaretsi

HPMC e na le thepa e ntle ea sekhomaretsi, e etsang hore e be molemo indastering ea kaho.HPMC e ka sebelisoa e le se tlamella lihlahisoa tse thehiloeng ho samente, joalo ka seretse le grout.E ka boela ea sebelisoa e le motenya ho li-adhesive tsa lithaele le li-filler tse kopanetsoeng.HPMC e ntlafatsa ts'ebetso le ts'ebetso ea lihlahisoa tsena ka ho fana ka ho khomarela hantle le ho boloka metsi.

Lisebelisoa tsa HPMC

HPMC e na le lits'ebetso tse ngata liindastering tse fapaneng, ho kenyelletsa:

Indasteri ea Lijo: HPMC e sebelisoa e le setepi, se tsitsisa, le emulsifier lihlahisoa tse ngata tsa lijo, joalo ka li-sauces, li-dressings le lintho tse halikiloeng.E ka boela ea sebelisoa ho etsa lifilimi tse jeoang le liaparo.

Indasteri ea Meriana: HPMC e sebelisoa e le letlapa le sekoaelo sa li-capsule, hammoho le se tlamellang, se senyang, le se fanang ka tokollo ea nako e telele mefuteng ea meriana.

Indasteri ea Litlolo: HPMC e sebelisoa e le sekontiri le se tsitsisa lihlahisoa tse ngata tsa litlolo, joalo ka litlolo, litlolo, le li-shampoo.

Indasteri ea Kaho: HPMC e sebelisoa e le ntho e tlamellang, e teteaneng, le e bolokang metsi lihlahisoa tse thehiloeng ho samente, joalo ka seretse, sekhomaretsi le sekhomaretsi sa lithaele.

Qetello

Hydroxypropyl methyl cellulose (HPMC) ke polymer e feto-fetohang e nang le lisebelisoa tse ngata tsa bohlokoa, tse kenyelletsang ho qhibiliha ha metsi, viscosity, botsitso ba mocheso, thepa ea ho etsa lifilimi le thepa ea sekhomaretsi.HPMC e sebelisoa liindastering tse ngata tse fapaneng, ho kenyeletsoa lijo, meriana, litlolo, le kaho.Bokhoni ba eona ba ho etsa lifilimi tse matla, tse feto-fetohang le ho ntlafatsa ts'ebetso le ts'ebetso ea lihlahisoa tse fapaneng li etsa hore e be motsoako oa bohlokoa mefuteng e mengata.HPMC e boetse e bolokehile hore e ka sebelisoa lijong le lihlahisoa tsa meriana 'me e amohetsoe ke mekhatlo e laolang lefats'e ka bophara.Kahoo, HPMC ke polymer ea bohlokoa ebile e sebelisoa haholo e bapalang karolo ea bohlokoa lits'ebetsong tse ngata tse fapaneng.