Owu a nụchara anụcha—emeghe—alkalization—etherification—neutralization—nkewa—ịsacha—nkewa—ịkpọ nkụ—ịkụpịa—ngwugwu—mechara oghere ngwaahịa HPMC: A na-emeghe owu a nụchara anụcha iji wepụ ígwè wee gwerie ya.Owu a nụchara anụcha a chụpụrụ dị n'ụdị ntụ ntụ, nke nwere nha nha 80 na nnyefe nke 100%.Ma ọ bụghị ya, ọ dị mfe ijikọta ọnụ n'oge usoro mmeghachi omume ma belata arụmọrụ etherification.
Alkalization: Tinye na powdered nụchara anụcha owu mgbe owu na-emeghe na inert ihe mgbaze, na rụọ ọrụ ya na alkali na rọrọ mmiri zasa na lattice nke nụchara anụcha owu ikwado penetration nke etherification gị n'ụlọnga ụmụ irighiri ma melite uniformity nke etherification mmeghachi omume.The alkali eji maka alkalization bụ a metal hydroxide ma ọ bụ ihe organic alkali.Ọnụ ego nke alkali agbakwunyere (site na uka, otu n'okpuru) bụ 0.1-0.6 ugboro nke owu a nụchara anụcha, mmiri dị nro agbakwunyere bụ 0.3-1.0 ugboro nke owu a nụchara anụcha;ihe mgbaze inert bụ ngwakọta nke mmanya na-aba n'anya na hydrocarbon, na ọnụ ọgụgụ nke inert ihe mgbaze agbakwunyere bụ 0.3-1.0 ugboro nke owu a nụchara anụcha.Oge 7-15 nke ahụ: Ihe mgbaze inert nwekwara ike ịbụ mmanya nwere 3-5 carbon atom (dị ka mmanya, propanol), acetone.Ọ nwekwara ike ịbụ aliphatic hydrocarbons na aromatic hydrocarbons;Ekwesịrị ịchịkwa okpomọkụ n'ime 0-35 ° C n'oge alkalization;oge alkalization bụ ihe dịka 1hr.Enwere ike ikpebi nhazi nke okpomọkụ na oge dịka ihe onwunwe na ngwaahịa chọrọ.
Etherification: Mgbe ọgwụgwọ alkalization gasịrị, n'okpuru ọnọdụ agụụ, a na-agbakwunye ihe na-eme ka etherification maka etherification, na onye na-ahụ maka etherification bụ propylene oxide.Iji belata oriri nke onye na-emepụta ihe, n'oge usoro nhazi ahụ, a na-agbakwunye onye na-ahụ maka etherification na ugboro abụọ, ọnụ ọgụgụ nke ntinye nke mbụ bụ 1-3.5 ugboro nke owu a nụchara anụcha, na ngụkọta nke mgbakwunye abụọ ahụ bụ 1.5. -4 ugboro nke owu a nụchara anụcha.ugboro.Mgbe ị gbakwunyere onye na-ahụ maka etherifying maka oge mbụ, kpalie na ≤30 ° C maka 45min-90min, wee bulie okpomọkụ ruo 50-100 ° C maka etherification maka 1-5h, wee jụụ ruo ≤30 ° C, nke abụọ. ka ịgbakwunye etherification na-akpali akpali, oge na-akpali akpali bụ 30-120min, wee kpoo ọkụ???Mee etherification, oge bụ 1-4h, n'oge a, owu a nụchara anụcha na-emeghachi omume n'ụzọ zuru ezu na onye na-ahụ maka etherification iji mepụta hYDROXYPROPYL METHYLCELLULLOSE HPMC.
Nchicha na nkwakọ ngwaahịa: ịkụpịa na sieving ngwaahịa a mịrị amị nke ihe a na-emepụta ugbu a, nha nke ngwaahịa HPMC nke emepụtara ugbu a mgbe a kụpịasịrị na sieving bụ ntupu 40 na nnyefe bụ 10096, ma ọ bụ dị ka mkpa onye ọrụ si dị.Mgbe ahụ kwakọba HPMC.
Oge nzipu: Nov-24-2022