Hydroxypropylmethylcellulose dị ala dochie anya (L-HPMC) bụ polymer na-agbanwe agbanwe, nke nwere ngwa na ụlọ ọrụ dị iche iche, gụnyere ọgwụ, nri, ihe owuwu, na ihe ịchọ mma.Ngwa a sitere na cellulose, polymer eke dị na mgbidi cell osisi.Iji ghọta hydroxypropyl methylcellulose dị ala dochie anya, mmadụ ga-akụtu aha ya wee nyochaa njirimara ya, ojiji ya, njikọ ya na mmetụta ya na ụlọ ọrụ dị iche iche.
1. Nghọta aha:
Hydroxypropyl methylcellulose (HPMC):
Cellulose bụ carbohydrate dị mgbagwoju anya mejupụtara nkeji glucose ma bụrụ akụkụ bụ isi nke mgbidi sel osisi.
Hydroxypropyl methylcellulose bụ ụdị cellulose gbanwetụrụ nke ejirila kemịkal mesoo iji webata hydroxypropyl na otu methyl.Nke a mgbanwe enhances ya solubility na ndị ọzọ na-achọsi ike Njirimara.
Ngbanwe dị ala:
Na-ezo aka na ngbanwe dị ala dị ala ma e jiri ya tụnyere ihe ndị ọzọ sitere na cellulose, dị ka ihe ngbanwe nke ukwuu dị ka hydroxyethyl cellulose (HEC).
2. Arụmọrụ:
Solubility:
L-HPMC na-agbaze na mmiri karịa cellulose.
Viscosity:
Enwere ike ịchịkwa viscosity nke ngwọta L-HPMC site n'ịgbanwe ogo nke nnọchi, na-eme ka ọ dị mma maka ọtụtụ ngwa.
Nhazi ihe nkiri:
L-HPMC nwere ike ịmepụta ihe nkiri dị mkpa, na-eme ka ọ baa uru na ngwa mkpuchi dị iche iche.
Nkwụsi ike okpomọkụ:
Polymer na-egosipụta nkwụsi ike nke okpomọkụ dị mma, na-enye aka na ntụgharị ya na usoro dị iche iche.
3. Nkwekọrịta:
Etherification:
Ngwakọta ahụ gụnyere etherification nke cellulose na propylene oxide iji webata otu hydroxypropyl.
Methylation nke na-esote ya na methyl chloride na-agbakwunye otu methyl na ọkpụkpụ azụ cellulose.
Enwere ike ịchịkwa ogo nke nnọchi n'oge njikọ iji nweta ihe ndị achọrọ.
4. Ngwa:
A. Ụlọ ọrụ ọgwụ:
Ihe nkedo na nkesa:
A na-eji ya dị ka ihe nkedo n'ụdị mbadamba ihe iji jikọta ihe ndị e ji emepụta ọnụ.
Na-arụ ọrụ dị ka onye na-agbasa iji kwalite nkwụsị nke mbadamba nkume na usoro nsị.
Ntọhapụ na-adịgide adịgide:
A na-eji L-HPMC mee ihe n'ụdị ntọhapụ a na-achịkwa, na-enye ohere ka ewepụtara ọgwụ ahụ nke nta nke nta ka oge na-aga.
Nkwadebe dị n'elu:
Achọpụtara na ude, gels na ointments, ọ na-enye viscosity ma na-eme ka mgbasawanye nke usoro.
B. Ụlọ ọrụ nri:
Ọkpụrụkpụ:
Na-abawanye viscosity nke nri ma na-emezi nhazi na mmetụta ọnụ.
stabilizer:
Na-akwalite nkwụsi ike nke emulsions na suspensions.
Nhazi ihe nkiri:
Ihe nkiri oriri maka nkwakọ nri.
C. Ụlọ ọrụ ihe owuwu:
Mortar na simenti:
Ejiri ya dị ka ihe na-ejigide mmiri na ihe ndị sitere na ciment.
Melite arụmọrụ na nrapanye nke usoro ngwa agha.
D. Nchọcha:
Ngwaahịa nlekọta onwe onye:
Achọtara na ude, lotions na shampoos iji nyere aka melite udidi na nkwụsi ike.
Ejiri ya dị ka onye na-emepụta ihe nkiri na ihe ịchọ mma.
5. Nlekọta:
FDA kwadoro:
A na-amatakarị L-HPMC dị ka nchekwa (GRAS) site na nchịkwa nri na ọgwụ US (FDA).
Nrube isi n'ụkpụrụ nchịkwa dị oke mkpa maka iji ya na ọgwụ na nri.
6. Ihe ịma aka na atụmanya n'ọdịnihu:
Nkwalite ndụ:
Ọ bụ ezie na a na-ewerekarị polymers nke dabeere na cellulose dị ka ihe na-adịghị mma, oke nbibi nke mkpụrụ ndụ cellulose gbanwetụrụ chọrọ nyocha ọzọ.
Nkwado:
Ịnweta akụrụngwa na-adịgide adịgide na ụzọ mmepụta ihe na gburugburu ebe obibi bụ ebe a na-elekwasị anya.
7. Nkwubi okwu:
Hydroxypropyl methylcellulose dị ala dochie anya na-egosipụta amamihe nke mgbanwe kemịkalụ n'iji njirimara nke polymers eke eme ihe.Ngwa ya dị iche iche na ụlọ ọrụ dị iche iche na-egosipụta mkpa ọ dị na nrụpụta ọgbara ọhụrụ.Dị ka ọganihu nkà na ụzụ na nkwado na-ewere ọnọdụ etiti, ịga n'ihu na nyocha na nchacha nke L-HPMC na ogige ndị yiri ya nwere ike ịkpụzi ọdịnihu nke sayensị ihe na omume ụlọ ọrụ.
Oge nzipu: Dec-26-2023