Hypromellose - He mea hoʻohana lāʻau lapaʻau kuʻuna

ʻO Hypromellose, i kapa ʻia ʻo hydroxypropyl methylcellulose (HPMC), he mea hoʻohana lāʻau lapaʻau kuʻuna i hoʻohana nui ʻia i ka ʻoihana lāʻau lapaʻau no nā kumu like ʻole.Aia ia i ka papa o cellulose ethers a ua loaʻa mai ka cellulose, he polymer maoli i loaʻa i loko o nā paia o nā mea kanu.Hoʻopili ʻia ʻo Hypromellose e ka mālama ʻana i ka cellulose me ka propylene oxide a me ka methyl chloride.

Eia kekahi mau hiʻohiʻona koʻikoʻi a me nā kuleana o hypromellose ma ke ʻano he lāʻau lapaʻau.

1. Binder: Hoʻohana pinepine ʻia ʻo Hypromellose ma ke ʻano he mea hoʻopaʻa i nā papa papa.Kōkua ia i ka hoʻopaʻa ʻana i nā mea lāʻau lapaʻau ikaika (API) a me nā mea kōkua ʻē aʻe, e hōʻoia i ka mālama ʻana o ka papa i kona ʻano a me kona kūpaʻa i ka wā hana a me ka lawelawe ʻana.
2. Agent Coating Agent: Hoʻohana ʻia ʻo Hypromellose ma ke ʻano he mea hoʻonaninani kiʻiʻoniʻoni e hāʻawi i kahi pale pale a maʻalahi i nā papa a me nā capsules.Hiki i kēia uhi ke uhi i nā ʻono maikaʻi ʻole, hoʻomaikaʻi i ka helehelena, pale i ka makū, a kāohi i ka hoʻokuʻu ʻana o ka lāʻau.
3. Matrix Former: Ma nā hoʻopuka hoʻokuʻu mau, hiki ke hoʻohana ʻia ka hypromellose ma ke ʻano he matrix mua.Hoʻokumu ia i kahi matrix e like me ka gel i ka wā e hoʻopili ai me ka wai, e kāohi ana i ka hoʻokuʻu ʻana o ka lāʻau i kahi manawa lōʻihi, no laila e hāʻawi ana i ka hana lāʻau lōʻihi.
4. Hoʻololi Viscosity: Hoʻohana pinepine ʻia ʻo Hypromellose e hoʻoponopono i ka viscosity o nā ʻano wai e like me ka hoʻokuʻu waha a me ka hoʻomākaukau ʻana.Kōkua ia i ka hoʻopaʻa ʻana i ka hoʻokuʻu ʻana, kaohi i ka rheology, a hoʻomaikaʻi i ka pourability a me ka hoʻolaha.
5. Disintegrant: I loko o kekahi mau papa hana, hiki i ka hypromellose ke hana ma ke ʻano he disintegrant, e hoʻoikaika ana i ka wāwahi wikiwiki ʻana o nā papa a i ʻole nā ​​capsules i loko o nā ʻāpana liʻiliʻi ke ʻike ʻia i ka wai i loko o ka ʻōpū o ka ʻōpū, a laila e hoʻomaʻamaʻa i ka hoʻopau ʻana a me ka absorption.
6. Emulsifier a me Stabilizer: Hiki i ka Hypromellose ke lawelawe ma ke ʻano he emulsifying agent a me ka stabilizer i nā emulsions a me nā creams, e kōkua ana i ka hoʻokumu ʻana i nā ʻano paʻa a me nā ʻano like ʻole no ka noi topical.
7. Mucoadhesive: I loko o ka ocular formulations a i ʻole nasal sprays, hypromellose hiki ke hana ma ke ʻano he mucoadhesive agent, e hoʻoikaika ana i ka hoʻopili ʻana i nā ʻili mucosal a hoʻolōʻihi i ka manawa pili o ka lāʻau me ka ʻiʻo i hoʻopaʻa ʻia.

ʻO ka holoʻokoʻa, ʻo hypromellose kahi mea hoʻohana lāʻau lapaʻau versatile no kona biocompatibility, non-toxicity, a me ka laulā o nā noi i nā ʻano dosage e like me nā papa, nā capsules, nā kiʻiʻoniʻoni, nā hoʻokuʻu, a me nā ʻaila.ʻO kāna mau waiwai he mea koʻikoʻi ia i ka hoʻokumu ʻana i nā huahana lāʻau lapaʻau like ʻole, e hāʻawi ana i ko lākou pono, kūpaʻa, a me ka ʻae ʻana i ka maʻi.