Umthelela wokuqukethwe kwe-methoxy nokuqukethwe kwe-hydroxypropoxy ku-HPMC

Okuqukethwe kwe-methoxy nokuqukethwe kwe-hydroxypropoxy ku-Hydroxypropyl Methylcellulose (HPMC) kuthonya kakhulu izakhiwo nokusebenza kwayo ezinhlelweni ezihlukahlukene.Nakhu ukuthi ipharamitha ngayinye iyithinta kanjani i-HPMC:

1. Okuqukethwe kwe-Methoxy:
   • Okuqukethwe kwe-methoxy kubhekisela kuzinga lokushintsha (DS) lamaqembu e-methoxy kumgogodla we-cellulose.Inquma i-hydrophobicity iyonke ye-HPMC.
   • Okuqukethwe okuphezulu kwe-methoxy kuholela ekuncibilikeni okuphezulu kwamanzi kanye nezinga lokushisa eliphansi le-gelation.Ama-HPMC anokuqukethwe okuphezulu kwe-methoxy ancibilika kalula emanzini abandayo, okuwenza afanelekele izinhlelo zokusebenza lapho kudingeka khona ukugeleza kwamanzi ngokushesha.
   • Okuqukethwe kwe-Methoxy kuthinta ikhono lokujiya le-HPMC.Ngokuvamile, i-DS ephezulu iphumela ekubonakaleni okuphezulu ekugxilweni okuphansi.Le ndawo inenzuzo ezinhlelweni ezifana nokunamathiswa, lapho kufunwa khona ukugcinwa kwamanzi okuthuthukisiwe kanye ne-viscosity.
   • Okuqukethwe okuphezulu kwe-methoxy nakho kungathonya izici zokwakha ifilimu, ukunamathela, nokuhambisana nezinye izithako.Kungase kube nomthelela ekwakhiweni kwamafilimu avumelana nezimo futhi ahlangene ezinhlelweni ezifana nezingubo namaphilisi emithi.
2. Okuqukethwe kwe-Hydroxypropoxy:
   • Okuqukethwe kwe-hydroxypropoxy kubhekisela ezingeni lokushintsha (DS) lamaqembu e-hydroxypropyl kumgogodla we-cellulose.Inquma i-hydrophilicity iyonke kanye nezindawo zokugcina amanzi ze-HPMC.
   • Ukwenyuka kokuqukethwe kwe-hydroxypropoxy kuthuthukisa amandla okugcina amanzi e-HPMC.Ithuthukisa amandla e-HPMC okugcina amanzi ekwenziweni, okuholela ekusebenzeni isikhathi eside kanye nokunamathela okungcono ezintweni zikasimende, ezifana nezinsimbi namathayela anamathelayo.
   • Okuqukethwe kwe-Hydroxypropoxy nakho kuthinta izinga lokushisa le-gelation kanye nezakhiwo zefilimu ze-HPMC.I-DS ephakeme yamaqembu e-hydroxypropyl yehlisa izinga lokushisa le-gelation futhi ingase iholele ekubunjweni kwefilimu okuthuthukisiwe kanye nokunamathela kuma-coatings kanye nezicelo zemithi.
   • Isilinganiso sokuqukethwe kwe-methoxy kokuqukethwe kwe-hydroxypropoxy sithonya ibhalansi iyonke yezakhiwo ze-hydrophilic kanye ne-hydrophobic ku-HPMC.Ngokulungisa lesi silinganiso, abakhiqizi bangakwazi ukulungisa ukusebenza kwe-HPMC ukuze kuhlangabezane nezidingo ezithile zohlelo lokusebenza, ezifana ne-viscosity, ukugcinwa kwamanzi, nokwakheka kwefilimu.

Kafushane, okuqukethwe kwe-methoxy nokuqukethwe kwe-hydroxypropoxy kwe-HPMC kudlala indima ebalulekile ekunqumeni ukuncibilika kwayo, amandla okuqina, ukugcinwa kwamanzi, izinga lokushisa le-gelation, izakhiwo zefilimu, ukunamathela, kanye nokuhambisana nezinye izithako.Ngokulawula le mingcele, abakhiqizi bangakhiqiza i-HPMC enezinhlobonhlobo zezakhiwo ezifanele ukusetshenziswa okuhlukahlukene ezimbonini ezifana nezokwakha, ezemithi, ukudla, izimonyo, nokunakekelwa komuntu siqu.