IHydroxypropyl methylcellulose (HPMC) iphuma ku-cellulose futhi isetshenziswa kakhulu ezimbonini ezahlukahlukene ngenxa yezakhiwo zayo ezihlukile.I-nonionic cellulose ether etholwe ngokushintsha ama-molecule e-cellulose yemvelo nge-propylene oxide ne-methyl chloride.I-HPMC ivamise ukuthengiswa ngendlela eyimpushana futhi incibilika emanzini ukuze kwakheke isixazululo esicacile, esingenambala, esine-viscous.
Izakhiwo eziyisisekelo ze-HPMC zihlukahlukene futhi ziwusizo ezinhlelweni eziningi.Ezinye zezindawo zayo eziphawuleka kakhulu zihlanganisa ukuziphatha kokugcinwa kwamanzi, ukujiya kanye nezakhiwo zokwenza ifilimu.I-HPMC futhi iyinhlanganisela ezinzile engaboli kalula ngenxa yokushisa noma ukuguga.
Enye yezinto ezibaluleke kakhulu ze-HPMC amandla ayo okugcina ama-molecule amanzi.Izakhiwo zayo ezigcina amanzi zibalulekile ekusetshenzisweni okuhlukahlukene, ikakhulukazi ezintweni zokwakha nezokwakha.Uma yengezwe kusimende noma kwezinye izinto zokwakha, i-HPMC ingabambezela inqubo yokomisa, ivimbele ukuthi kome kakhulu futhi kushwabane ngokushesha okukhulu.Ngokugcina ama-molecule amanzi, i-HPMC ikhuthaza ukuphulukiswa okufanele kanye nokufakwa kwe-hydration, ngaleyo ndlela ikhulise amandla nokuqina komkhiqizo oqediwe.
Enye impahla ebalulekile ye-HPMC yikhono layo lokujiya.I-HPMC ishubisa uketshezi ngokwakha inethiwekhi yejeli lapho incibilika emanzini.Ukujiya kubalulekile ezimbonini eziningi ezidinga amazinga athile e-viscosity wemikhiqizo.Isibonelo, embonini yokudla, i-HPMC isetshenziswa njenge-ejenti yokuqina kumasoso nezingubo zokugqoka ukuze kuthuthukiswe ukuthungwa nokuvumelana kwazo.Embonini yezemithi, i-HPMC isetshenziswa njengesihlanganisi ekwakhiweni kwamathebulethi ukuze kuthuthukiswe ukuhlangana kwawo nokuhlukana kwawo.
I-HPMC futhi iyi-ejenti enhle kakhulu yokwenza amafilimu.Uma incibilika emanzini, ingakha ifilimu encane, esobala, eguquguqukayo.Ikhono lokwenza ifilimu le-HPMC liyenza ibe isithako esifanelekile sokukhiqizwa kwamafomu omthamo oqinile womlomo kanye nama-transdermal patches.Izici ezenza ifilimu ze-HPMC zisiza ukuthuthukisa ukumuncwa kwezidakamizwa ngokunikeza umgoqo phakathi komuthi nendawo ezungezile.
Ngaphezu kokugcinwa kwamanzi, ukuqina kanye nezakhiwo zefilimu, i-HPMC inezinye izinto ezifiselekayo.Isibonelo, i-HPMC ibonisa izici ezinhle ze-rheological, okusho ukuthi ingasetshenziswa ukulawula ukugeleza kanye ne-viscosity yoketshezi.Umthamo wayo ophezulu wokubopha uwenza ukwazi ukuhlanganisa izinhlayiya nezinhlayiya ezixazululweni, okuwenza asebenze kahle ekwenziweni kokumiswa.
I-HPMC iyinhlanganisela ezinzile enokumelana okuhle nokushisa nokumelana nokuguga.Ayisabeli nezinye izinto, okwenza ihambisane nezinto eziningi ezahlukene.Ukuzinza kwayo kuyenza ilungele ukusetshenziswa emikhiqizweni edinga impilo yeshelufu ende.
I-HPMC isetshenziswa ezimbonini eziningi, okuhlanganisa ezokwakha, ezemithi, imikhiqizo yokunakekela abantu, ukudla kanye nezimonyo.Ekwakhiweni, isetshenziswa njenge-ejenti yokugcina amanzi kusimende, ukhonkolo nodaka ukuze kuthuthukiswe ukusebenza kanye nesikhathi sokusetha.Kwezemithi, i-HPMC isetshenziswa njenge-binder, disintegrant, kanye ne-ejenti yokukhululwa elawulwayo ekwenziweni kwethebhulethi.Ibuye isetshenziswe njenge-viscosity modifier kuzixazululo ze-ophthalmic.
Embonini yokunakekelwa komuntu siqu, i-HPMC isetshenziswa njenge-ejenti yokuqina kuma-shampoos, izinto zokuthambisa kanye neminye imikhiqizo yobuhle ukuze kuthuthukiswe ukuthungwa kanye ne-viscosity.Ibuye isetshenziswe njenge-ejenti yokwenza ifilimu ezimonyoni ukusiza ukuthuthukisa ukusabalalisa okulinganayo kwezimibalabala kanye nokuvimbela ukunqwabelana.
Embonini yokudla, i-HPMC isetshenziswa njenge-thickener, emulsifier and stabilizer emikhiqizweni efana nemikhiqizo yobisi, amasobho kanye neziphuzo.I-HPMC iphinde isetshenziswe njenge-ejenti yokuhlanganisa kanye ne-ejenti eyenza amafilimu ezitsheni zezithelo, zemifino kanye namaswidi.
I-HPMC iyinhlanganisela eguquguqukayo enezinto eziningi ezifiselekayo ezifana nokugcinwa kwamanzi, ukujiya, kanye nezakhiwo zokwenza ifilimu.Ngenxa yezakhiwo zayo ezihlukene, isetshenziswa kabanzi ezimbonini ezihlukahlukene, kuhlanganise nezokwakha, ezemithi, imikhiqizo yokunakekelwa komuntu siqu, ukudla nezimonyo.I-HPMC iyinhlanganisela ezinzile engasabelani nezinye izinto, iyenze ihambisane nemikhiqizo eminingi eyahlukene.Ngakho-ke, i-HPMC inohlu olubanzi lwezicelo ezingase zibe khona kanye namathemba abanzi ezimbonini ezahlukahlukene.
Isikhathi sokuthumela: Sep-13-2023