Ọna iṣelọpọ immersion ipilẹ jẹ ọna ti o wọpọ fun iṣelọpọ hydroxypropyl methyl cellulose (HPMC).Ọna yii jẹ ifarahan ti cellulose pẹlu sodium hydroxide (NaOH) ati lẹhinna pẹlu propylene oxide (PO) ati methyl kiloraidi (MC) labẹ awọn ipo kan.
Ọna immersion alkaline ni anfani ti iṣelọpọ HPMC pẹlu iwọn giga ti aropo (DS), eyiti o pinnu awọn ohun-ini rẹ gẹgẹbi solubility, viscosity, ati gelation.Ọna naa pẹlu awọn igbesẹ wọnyi:
- Igbaradi ti Cellulose
A gba cellulose lati awọn orisun adayeba gẹgẹbi igi, owu, tabi awọn ohun elo ọgbin miiran.Cellulose ti wa ni mimọ ni akọkọ ati lẹhinna mu pẹlu NaOH lati ṣe iṣuu soda cellulose, eyiti o jẹ agbedemeji ifaseyin ni iṣelọpọ ti HPMC.
- Idahun ti Sodium Cellulose pẹlu Propylene Oxide (PO)
Awọn iṣuu soda cellulose lẹhinna ṣe atunṣe pẹlu PO ni iwaju ayase kan gẹgẹbi tetramethylammonium hydroxide (TMAH) tabi sodium hydroxide (NaOH) ni awọn iwọn otutu giga ati awọn titẹ.Awọn abajade esi ni dida hydroxypropyl cellulose (HPC).
- Idahun ti HPC pẹlu Methyl Chloride (MC)
HPC naa jẹ idahun pẹlu MC ni iwaju ayase kan gẹgẹbi sodium hydroxide (NaOH) tabi hydrochloric acid (HCl).Idahun naa ṣe abajade ni dida hydroxypropyl methyl cellulose (HPMC).
- Fifọ ati gbigbe
Lẹhin iṣesi, ọja naa ti wẹ pẹlu omi ati ki o gbẹ lati gba HPMC.Ọja naa jẹ mimọ nigbagbogbo nipa lilo lẹsẹsẹ ti sisẹ ati awọn igbesẹ centrifugation lati yọkuro awọn aimọ.
Ọna immersion ipilẹ ni awọn anfani pupọ lori awọn ọna miiran, pẹlu DS giga ati mimọ, iye owo kekere, ati irọrun scalability.Ọna naa tun le ṣee lo lati ṣe agbejade HPMC pẹlu awọn ohun-ini oriṣiriṣi nipasẹ yiyipada awọn ipo iṣesi bii iwọn otutu, titẹ, ati ifọkansi.
Sibẹsibẹ, awọn ọna tun ni o ni diẹ ninu awọn drawbacks.Lilo NaOH ati MC le jẹ ailewu ati awọn ewu ayika, ati ilana iṣelọpọ le jẹ akoko-n gba ati nilo agbara nla.
Ni ipari, ọna iṣelọpọ immersion ipilẹ jẹ ọna lilo pupọ fun iṣelọpọ HPMC.Ọna naa jẹ ifarabalẹ ti cellulose pẹlu NaOH, PO, ati MC labẹ awọn ipo kan, atẹle nipa isọdi ati gbigbe.Lakoko ti ọna naa ni diẹ ninu awọn ailagbara, awọn anfani rẹ jẹ ki o jẹ yiyan olokiki fun ile-iṣẹ ati awọn ohun elo elegbogi.
Akoko ifiweranṣẹ: Oṣu Kẹrin Ọjọ 23-2023