I-HPMC isebenzisa kwiipilisi

I-HPMC (i-hydroxypropyl methylcellulose) yinto esetyenziswa ngokubanzi kwishishini loxubo mayeza.I-polymer engeyiyo i-ionic, i-soluble water-soluble evela kwi-cellulose, kwaye isetyenziswe kwiintlobo ezahlukeneyo zokuqulunqa amayeza, kuquka iipilisi, iipilisi, ii-creams, i-ointments, kunye nokumiswa.I-HPMC sisixhobo esifanelekileyo sokwenziwa kweepilisi kuba ayinayo ityhefu, ayithukuthezi, kwaye ineempawu ezigqwesileyo zokubophelela kunye nokwenza ifilim.

I-HPMC isetyenziswa kwiipilisi ngenxa yezizathu ezahlukeneyo.Okokuqala, isetyenziswa njengesibophelelo sokubamba ithebhulethi kunye.I-HPMC yinto ebonakalayo ebonakalayo enokwenza ibhondi eyomeleleyo phakathi kwezithako ezisebenzayo kunye nezinye ii-excipients kwi-tablet.Oku kunceda ukuqinisekisa ukuba ithebhulethi izinzile kwaye ayiphuli ngexesha lokuvelisa okanye ukugcinwa.

Okwesibini, i-HPMC isetyenziswa njenge-disintegrant kwiipilisi.Xa ithebhulethi ithathwa ngomlomo, kufuneka ikwazi ukuhlukana ngokukhawuleza ukuze ikhulule izithako ezisebenzayo.I-HPMC inceda ukuququzelela le nkqubo ngokufunxa amanzi kunye nokudumba, okubangela ukuba ithebhulethi ihlukane.Oku kuqinisekisa ukuba izithako ezisebenzayo zikhutshwa ngokukhawuleza nangempumelelo.

Okwesithathu, i-HPMC isetyenziswa njenge-lubricant kwiipilisi.I-Lubricants inceda ukunciphisa ukungqubuzana phakathi kwethebhulethi kunye nodonga lokufa ngexesha lenkqubo yokuxinzelela, enceda ukuthintela ukunamathela kunye nokunamathela.Oku kunceda ukuqinisekisa ukuba iipilisi zinobukhulu obufanayo kunye nokumila.

Okwesine, i-HPMC isetyenziswa njenge-glidant kwiipilisi.I-Glidants inceda ukunciphisa ukunyanzeliswa komphezulu we-powder particles, okunceda ukuqinisekisa ukuba i-powder ihamba ngokukhululekile ngexesha loxinzelelo.Oku kunceda ukuqinisekisa ukuba iipilisi zinobukhulu obufanayo kunye nokumila.

Okokugqibela, i-HPMC isetyenziswa njenge-arhente yokugquma kwiipilisi.Ii-coating agents zinceda ukukhusela ithebhulethi kumswakama kunye nezinye izinto ezisingqongileyo, ezinceda ukuqinisekisa ukuba ithebhulethi ihlala izinzile ngexesha lokugcinwa.

Isishwankathelo, i-HPMC yinto esetyenziswa ngokubanzi kwishishini loxubo mayeza, kwaye isetyenziswa kuqulunqo lwethebhulethi ngezizathu ezahlukeneyo.Isetyenziswe njenge-binder, i-disintegrant, i-lubricant, i-glidant, kunye ne-agent yokugqoka, enceda ukuqinisekisa ukuba iipilisi zinobukhulu obufanayo kunye nokuma, kwaye zihlala zizinzile ngexesha lokugcinwa.