1. Tšebeliso e ka sehloohong ea hydroxypropyl methylcellulose (HPMC) ke efe?
Karabo: HPMC e sebelisoa haholo ka thepa ea kaho, liphahlo, li-resin tsa maiketsetso, lirafshoa, meriana, lijo, masela, temo, litlolo, koae le liindasteri tse ling.HPMC e ka aroloa ka sehlopha sa kaho, sehlopha sa lijo le sehlopha sa meriana ho latela sepheo.Hajoale, boholo ba lihlahisoa tsa lapeng ke tsa boemo ba kaho.Sebakeng sa kaho, phofo ea putty e sebelisoa ka bongata, hoo e ka bang 90% e sebelisetsoa putty powder, 'me e setseng e sebelisetsoa seretse sa samente le sekhomaretsi.
2. Ho na le mefuta e mengata ea hydroxypropyl methylcellulose (HPMC), 'me ke phapang efe ea tšebeliso ea bona?
Karabo: HPMC e ka aroloa ka mofuta oa hang-hang le mofuta oa ho qhibiliha o chesang.Lihlahisoa tsa mofuta oa hang-hang li hasana ka potlako metsing a batang ebe li nyamela ka metsing.Ka nako ena, mokelikeli ha o na viscosity hobane HPMC e qhalakanngoa feela metsing ntle le ho qhibiliha ha sebele.Hoo e ka bang metsotso e 2, viscosity ea mokelikeli e ntse e eketseha butle-butle, e etsa "viscous colloid" e hlakileng.Lihlahisoa tse chesang, ha li kopane le metsi a batang, li ka qhalana ka potlako metsing a chesang 'me tsa nyamela metsing a chesang.Ha mocheso o theohela ho mocheso o itseng, viscosity e tla hlaha butle-butle ho fihlela e etsa "viscous colloid" e hlakileng.Mofuta oa hot-melt o ka sebelisoa feela ka phofo ea putty le seretse.Ka sekhomaretsi sa metsi le pente, ho tla ba le ts'ebetso ea lihlopha 'me e ke ke ea sebelisoa.Mofuta oa hang-hang o na le mefuta e mengata e fapaneng ea lits'ebetso.E ka sebelisoa ka phofo ea putty le seretse, hammoho le sekhomaretsi sa metsi le pente, ntle le li-contraindications.
3. Mekhoa ea ho qhibiliha ea hydroxypropyl methylcellulose HPMC ke efe?
Karabo: Mokhoa oa ho qhibiliha ha metsi a chesang: Kaha HPMC ha e qhibilihe metsing a chesang, HPMC e ka qhalakanngoa ka ho lekana metsing a chesang qalong, ebe e qhibiliha ka potlako ha e pholile.Mekhoa e 'meli e tloaelehileng e hlalosoa ka tsela e latelang:
1), eketsa 1/3 kapa 2/3 ea palo e hlokahalang ea metsi ka har'a setshelo, 'me ue chese ho 70 ° C, qhala HPMC ho latela mokhoa oa 1),' me u lokise slurry ea metsi a chesang;joale eketsa palo e setseng ea metsi a batang ho metsi a chesang a slurry, motsoako o ne o pholile ka mor'a ho hlohlelletsa.
Mokhoa oa ho kopanya phofo: kopanya phofo ea HPMC le bongata ba lintho tse ling tse phofo, kopanya ka botlalo le motsoako, ebe u eketsa metsi ho qhibiliha, ebe HPMC e ka qhibiliha ka nako ena ntle le ho kopana, hobane ho na le HPMC e nyenyane feela ho e 'ngoe le e' ngoe e nyenyane. hukung Powder, e tla qhibiliha hang hang ha e kopana le metsi.——Baetsi ba phofo le seretse ba sebelisa mokhoa ona.[Hydroxypropyl methylcellulose (HPMC) e sebelisoa e le ntho e thibelang metsi le ho boloka metsi seretseng sa putty powder.
2) Kenya palo e hlokahalang ea metsi a chesang ka har'a sets'oants'o 'me ue chese ho fihlela ho 70°C.Hydroxypropyl methylcellulose e ile ea kenngoa butle-butle tlas'a ho sisinyeha butle-butle, qalong HPMC e ne e phaphametse holim'a metsi, 'me butle-butle e theha slurry, e neng e pholile tlas'a ho sisinyeha.
Nako ea poso: Dec-01-2022