HPMC MOEKETSI
Hydroxypropyl Methylcellulose (HPMC) ke cellulose ether e nkiloeng ho selulose ea tlhaho, haholo-holo lehong kapa k'hothone, ka letoto la ts'ebetso ea lik'hemik'hale.Mona ke kakaretso ea metsoako le thepa ea HPMC:
- Cellulose: Cellulose ke motsoako o ka sehloohong oa HPMC.Ke polysaccharide ea tlhaho e nang le likarolo tse pheta-phetoang tsa tsoekere tse kopantsoeng hammoho ka liketane tse telele.Cellulose e sebetsa e le mokokotlo oa HPMC mme e fana ka botšepehi ba sebopeho.
- Methylation: Mokokotlo oa cellulose o fetotsoe ka lik'hemik'hale ka mokhoa o bitsoang methylation, moo methyl chloride e sebetsanang le cellulose ka pel'a alkali ho hlahisa lihlopha tsa methyl (-CH3) holim'a ketane ea cellulose.Ts'ebetso ena ea methylation e bohlokoa bakeng sa ho ntlafatsa ho qhibiliha ha metsi le lisebelisoa tse ling tsa selulose.
- Hydroxypropylation: Ho phaella ho methylation, lihlopha tsa hydroxypropyl (-CH2CHOHCH3) li ka boela tsa kenngoa ketane ea cellulose ka hydroxypropylation.Sena se tsoela pele ho fetola thepa ea selulose, ho ntlafatsa ho boloka metsi, bokhoni ba ho etsa filimi, le litšobotsi tse ling.
- Etherification: Kenyelletso ea lihlopha tsa methyl le hydroxypropyl holim'a ketane ea cellulose e tsejoa e le etherification.Etherification e fetola sebopeho sa lik'hemik'hale tsa selulose, e leng se etsang hore ho thehoe HPMC e nang le thepa e ikhethang e loketseng lits'ebetso tse fapaneng.
- Thepa ea 'Mele: HPMC ha e le hantle ke phofo e tšoeu ho ea ho e tšoeu, e sa nkheng, ebile e sa latsoeheng.E qhibiliha ka metsing a batang 'me e etsa litharollo tse hlakileng kapa tse fokolang hanyane ho itšetlehile ka mahloriso le kereiti.HPMC e bonts'a ts'ebetso e ntle ea ho boloka metsi, e teteaneng, ho etsa lifilimi, le thepa ea ts'ebetso ea holim'a metsi, e etsa hore e be ea bohlokoa liindastering tse fapaneng, ho kenyeletsoa kaho, meriana, lijo le litlolo.
Ka kakaretso, metsoako e ka sehloohong ho HPMC ke selulose, methyl chloride (bakeng sa methylation), le propylene oxide (bakeng sa hydroxypropylation), hammoho le li-catalysts tsa alkali le li-additives tse ling tse sebelisoang ts'ebetsong ea tlhahiso.Metsoako ena e ba le karabelo ea lik'hemik'hale ho hlahisa HPMC e nang le thepa e ikhethileng e etselitsoeng ho fihlela litlhoko tsa lits'ebetso tse fapaneng.
Nako ea poso: Feb-28-2024