Kodi madontho a HPMC amagwiritsa ntchito chiyani?

1. Basic makhalidwe a HPMC akutsikira

HPMC ndi non-ionic cellulose ether yokhala ndi zabwino izi:

Wamphamvu thickening ndi adhesion: kumathandiza kuonjezera zokhala nthawi mankhwala padziko m`deralo zimakhala.

Good biocompatibility: zosakwiyitsa, sizimayambitsa ziwengo, ndipo ndizoyenera kumadera ovuta monga maso.

Zowoneka bwino komanso zopanda utoto, kukhazikika kwa pH kwabwino: koyenera kugwiritsidwa ntchito ngati chonyamulira chotsitsa, sikumakhudza masomphenya ndi ntchito zathupi.

Kutulutsidwa kokhazikika: kumatha kuwongolera kuchuluka kwa mankhwalawa ndikutalikitsa mphamvu yake.

Makhalidwewa amapangitsa HPMC kukhala chothandizira pakukonzekera kutsika, makamaka pamene kumasulidwa kosalekeza kapena mafuta odzola amafunika.

 

2. Kugwiritsa ntchito kwambiri madontho a HPMC

2.1. Misozi Yopanga / Mafuta opangira maso

Ichi ndi chimodzi mwazofala kwambiri zogwiritsa ntchito madontho a HPMC. Misozi yochita kupanga imagwiritsidwa ntchito makamaka pochepetsa maso owuma, kutopa kwamaso, kusapeza bwino komwe kumadza chifukwa cha kuvala kwa lens kwanthawi yayitali, ndi zovuta zina. HPMC imagwira ntchito zotsatirazi pamadontho amaso:

Kutengera misozi yachilengedwe: HPMC ili ndi madzi osungira bwino komanso mafuta, imatha kutsanzira misozi yachilengedwe, ndikuchotsa maso owuma.

Kuchulukitsa nthawi yomangirira mankhwala: Popanga filimu yopyapyala, nthawi yosungiramo mankhwalawa pamawonekedwe amaso imakulitsidwa, ndipo mphamvu zake zimatheka.

Kuthandizira zosakaniza zina: Nthawi zambiri amagwiritsidwa ntchito ndi zothira mafuta monga PVA (polyvinyl alcohol) ndi PEG (polyethylene glycol) kuti awonjezere kumva kugwiritsidwa ntchito.

Zinthu wamba monga "hydroxypropyl methylcellulose eye drops" ndi "Runjie artificial tears" zonse zili ndi zosakaniza za HPMC.

 

2.2. Thickener kwa ophthalmic achire madontho a maso

HPMC sangathe kugwiritsidwa ntchito ngati lubricant, komanso kawirikawiri ntchito achire diso madontho, monga odana ndi yotupa mankhwala, mankhwala, khungu mankhwala, etc., kuti:

Limbikitsani kukhazikika kwa mankhwala;

Kuchepetsa chilolezo cha mankhwala;

Chepetsani kuchuluka kwa mlingo ndikuwongolera kutsatira kwa odwala.

Mwachitsanzo, HPMC nthawi zina anawonjezera levofloxacin diso madontho ntchito kuchiza conjunctivitis kutalikitsa zochita za mankhwala nthawi mu conjunctival sac.

 

2.3. Otolaryngology imachepa

M'madontho a m'mphuno ndi madontho a khutu, HPMC imagwiritsidwa ntchito ngati chowonjezera kapena chotulutsa chokhazikika pazifukwa zotsatirazi:

Auricular anti-infective drops: HPMC imathandiza kuti mankhwalawa akhalebe mu ngalande ya khutu ndikuwonjezera mphamvu ya bactericidal.

Madontho a Ninitis: Katundu womasulidwa wokhazikika amalola kuti mankhwala oletsa kutupa kapena anti-allergenic akhale ndi zotsatira zokhalitsa komanso amachepetsa kutaya kwa mankhwala chifukwa cha mphuno.

 

2.4. Oral mucosal madontho

Pochiza zilonda zam'kamwa kapena mucositis, mankhwala ena amapangidwa kukhala madontho kuti athe kuponyedwa mwachindunji pamalo otupa. HPMC imatha kupereka zomatira ndikumasulidwa kosalekeza, kulola kuti mankhwalawa azichita bwino pamalo omwe akhudzidwa.

 

3. Ubwino wa kapangidwe ka mawonekedwe a HPMC madontho

HPMC sikuti ndi thickener mu chilinganizo dontho, komanso kiyi zinchito chonyamulira. Ubwino wake ukuwonekera mu:

Chitetezo chachikulu: sichimatengedwa ndi thupi la munthu, palibe poizoni wamtundu uliwonse, woyenera kugwiritsidwa ntchito kwa nthawi yayitali.

Limbikitsani chidziwitso cha odwala: palibe kukwiyitsidwa, omasuka kugwiritsa ntchito, makamaka oyenera odwala omwe ali ndi chidwi monga makanda ndi okalamba.

Kugwirizana kwabwino: kumatha kukhala limodzi ndi zinthu zosiyanasiyana zogwira ntchito, osati zophweka kupangitsa kuti ziwonongeke.

Zosavuta kukonzekera ndikusunga: Madontho a HPMC amakhala okhazikika komanso owonekera bwino kutentha kwa chipinda ndipo ndi osavuta kupanga mafakitale.