Hydroxypropyl starch ether (HPS) is a modified starch derivative created through the reaction of starch with propylene oxide, resulting in a substance that retains the characteristics of starch while having enhanced solubility, stability, and functionality. HPS is widely used in various industries, including food, pharmaceuticals, cosmetics, and construction, due to its versatile properties.

Chemical Structure and Modification
HPSE is produced by etherifying starch molecules with hydroxypropyl groups (–CH2CH(OH)CH3), which are introduced via the reaction with propylene oxide. This modification alters the starch’s chemical structure, improving its solubility in water and enhancing its ability to form stable solutions, especially under varying temperature and pH conditions. This transformation makes HPS more suitable for a wide range of applications compared to native starch.
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Key Properties of Hydroxypropyl Starch Ether
The primary performance characteristics of HPSE include:
Solubility and Gelation
HPS is water-soluble, unlike native starch, which forms gels upon heating in water. This solubility makes HPS valuable in applications where the formation of a gel is not desirable, such as in certain food products, pharmaceutical formulations, and industrial processes. Moreover, HPS can form stable gels at different temperatures and in the presence of salts, which is beneficial for certain applications in food and pharmaceuticals.
Viscosity
HPS solutions exhibit high viscosity at low concentrations, making it a useful thickening agent. The viscosity of HPS can be adjusted based on the degree of hydroxypropyl substitution, which influences the water retention capacity and the overall thickness of the solution. Its ability to modify viscosity over a wide range is crucial in various applications, including as a thickener in cosmetics and food products.
Stability
HPS demonstrates excellent stability under a variety of conditions, including high temperatures, low and high pH environments, and the presence of electrolytes. This stability makes it an ideal candidate for use in both food and non-food formulations that require long shelf-life and consistent performance, such as in cosmetics and pharmaceuticals.

Film-forming and Binding Properties
Due to its ability to form films and its binding capabilities, HPS is often utilized in coatings, tablet formulations, and other products where a film-forming agent is required. Its adhesive and binding properties make it a popular choice for use in food coatings, pharmaceutical tablets, and other applications where these characteristics are essential.
Non-toxic and Biodegradable
HPS is generally regarded as safe (GRAS) for use in food products and is biodegradable, making it an environmentally friendly alternative to synthetic polymers. This property contributes to its increasing demand in sustainable applications, such as biodegradable packaging and environmentally responsible pharmaceuticals.
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Applications of Hydroxypropyl Starch Ether
Food Industry
HPS is commonly used in the food industry as a thickening agent, stabilizer, and emulsifier. Its ability to form stable solutions and retain moisture makes it ideal for use in soups, sauces, dressings, and desserts. It is also used in the production of instant foods and processed foods, where it helps improve texture and shelf-life. HPS ability to prevent syneresis (the separation of liquid from gel) enhances the quality and consistency of food products.
Examples:
- Soups and sauces: Provides the desired thickness without changing the flavor or appearance.
- Baked goods: Enhances moisture retention, extending shelf life.
- Desserts and ice cream: Improves texture and prevents ice crystallization.
Pharmaceutical Industry
HPS is widely used in the pharmaceutical sector as a binder and disintegrant in tablet formulations. Its ability to form stable gels under varying conditions is advantageous in controlled-release formulations, where it helps regulate the release of active pharmaceutical ingredients (APIs). HPS is also used in suspensions and emulsions as a stabilizer.
Examples:
- Tablets: Acts as a binder and disintegrant.
- Suspensions: Enhances stability and uniformity of the formulation.
- Topical formulations: Used as a thickener and stabilizer.
Cosmetics Industry
HPS is a key ingredient in many cosmetic formulations, particularly in lotions, creams, shampoos, and conditioners, where it serves as a thickening agent and stabilizer. Its ability to form films helps improve the texture and appearance of products. Additionally, HPS moisturizing properties contribute to its use in skin care products.
Examples:
- Creams and lotions: Improves texture and stability.
- Shampoos and conditioners: Adds thickness and improves the sensory experience.
- Makeup products: Enhances the stability and performance of emulsions.
Construction Industry
HPS is also used in the construction industry as an additive in cement, plaster, and tile adhesives. It improves the workability, spreadability, and water retention of these products. HPS ensures that the adhesives remain pliable and easy to apply, enhancing the overall quality of the construction materials.
Examples:
- Cement and plaster: Improves workability and adhesion.
- Tile adhesives: Enhances bonding strength and water retention.

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Performance Characteristics of Hydroxypropyl Starch Ether
| Property | Description | Applications |
| Solubility | Water-soluble, enhanced compared to native starch. | Food products, pharmaceutical formulations, cosmetics. |
| Viscosity | High viscosity at low concentrations. Adjustable based on hydroxypropyl substitution. | Food thickeners, cosmetics, industrial applications. |
| Gelation | Forms gels at various temperatures and salt concentrations. | Food products (puddings, sauces), pharmaceuticals (controlled-release tablets). |
| Stability | Stable under high/low pH, elevated temperatures, and electrolyte presence. | Long shelf-life in food and pharmaceutical products, stabilizer in cosmetics. |
| Film-forming | Forms flexible, water-resistant films. | Coatings, adhesives, tablet formulations. |
| Binding and Adhesion | Strong binding properties for tablets, granules, and powders. | Pharmaceuticals, food products, and cosmetic formulations. |
| Biodegradability | Biodegradable and environmentally friendly. | Sustainable packaging, green pharmaceuticals. |
| Non-toxicity | Generally recognized as safe (GRAS) for food applications. | Food additives, pharmaceutical excipients. |
HPS is a highly versatile material with a broad range of applications across various industries due to its unique set of properties. Its enhanced solubility, stability, viscosity control, and biodegradability make it an attractive option in food processing, pharmaceuticals, cosmetics, and construction. As consumer demand for environmentally friendly and sustainable products continues to rise, HPS role is expected to grow, further demonstrating its importance as a functional and performance-enhancing ingredient.
Post time: Jun-12-2025