Hydroxypropyl Methylcellulose (HPMC) pụtara dị ka polymer sịntetik a ma ama nke nwere ọtụtụ ngwa n'ofe ụlọ ọrụ dị iche iche, gụnyere ọgwụ, ihe owuwu, nri, na ịchọ mma.Ngwongwo ya pụrụ iche na-eme ka ọ bụrụ ihe dị mkpa na usoro chọrọ ngbanwe viscosity, nhazi ihe nkiri, yana dịka onye na-ejikọta ya.
Njikọ nke HPMC:
A na-enweta HPMC site na cellulose, polysaccharide na-emekarị na mgbidi cell.Agbanyeghị, HPMC na-enweta mgbanwe mgbanwe kemịkalụ dị iche iche iji welie akụrụngwa ya na ntụgharị ya, na-eme ka ọ bụrụ polymer sịntetịt.Njikọ a na-agụnye etherification nke cellulose site na mmeghachi omume na propylene oxide na methyl chloride, na-eduga na iwebata hydroxypropyl na methyl otu n'ime ọkpụkpụ azụ cellulose.Usoro a na-agbanwe ọdịdị anụ ahụ na nke kemịkalụ nke cellulose, na-ebute polymer nwere mma solubility, nkwụsi ike, na ihe na-emepụta ihe nkiri.
Njirimara nke HPMC:
Hydrophilicity: HPMC na-egosipụta oke mmiri solubility n'ihi ọnụnọ nke hydroxypropyl na methyl otu, nke na-enye ihe onwunwe hydrophilic na polymer.Njirimara a na-eme ka ọ dị mma maka iji ya mee ihe na mmiri mmiri dị ka ọgwụ, ebe mgbasa ngwa ngwa na-achọsi ike.
Mgbanwe viscosity: Otu n'ime àgwà kachasị mkpa nke HPMC bụ ikike ya ịgbanwe viscosity nke ngwọta mmiri.Ogo nke nnọchi (DS) nke hydroxypropyl na methyl dị iche iche na-emetụta viscosity nke ngwọta HPMC, na-enye ohere maka njikwa ziri ezi na njirimara rheological nke usoro.Ngwongwo a na-achọta ngwa na ụlọ ọgwụ, ebe a na-eji HPMC eme ihe dị ka ihe na-eme ka ọ sie ike na nkwusioru ọnụ, gels topical, na ngwọta anya.
Nhazi ihe nkiri: HPMC nwere ike ịmepụta ihe nkiri na-agbanwe agbanwe, na-agbanwe agbanwe mgbe agbazere na mmiri ma ọ bụ ihe mgbaze organic.Ihe nkiri ndị a na-egosipụta ihe mgbochi dị mma, na-eme ka ha dị mma maka mkpuchi mbadamba nkume, na-ekpuchi ihe ndị na-arụ ọrụ, na ịmepụta usoro nnyefe ọgwụ na-achịkwa.
Thermal Stability: HPMC na-egosiputa ezigbo nkwụsi ike nke okpomọkụ, na-ejigide iguzosi ike n'ezi ihe nhazi ya n'elu oke okpomọkụ.Njirimara a bara uru na ngwa ndị dị ka ihe owuwu ụlọ, ebe HPMC na-eji dị ka ihe na-esi ísì na mmiri na-ejide mmiri na ngwaahịa simenti.
Biocompatibility: HPMC bụ ihe dakọtara na ya anaghị egbu egbu, na-eme ka ọ dabara adaba maka iji ọgwụ, ngwaahịa nri, na ihe ịchọ mma.A mụọla profaịlụ nchekwa ya nke ọma, ma kwadokwara ya maka ojiji na ikike nchịkwa dị iche iche n'ụwa niile.
Ngwa nke HPMC:
Pharmaceuticals: HPMC na-ahụta ojiji dị ukwuu na ụlọ ọrụ ọgwụ n'ihi ngbanwe ya na biocompatibility ya.A na-eji ya arụ ọrụ dị ka onye na-ekekọta ihe na mbadamba mbadamba, ihe ngbanwe viscosity na nkwusioru na emulsions, na ihe nkiri nke bụbu na fim ọnụ na mkpuchi.Na mgbakwunye, a na-eji hydrogels sitere na HPMC na akwa ọnya, patches transdermal, na usoro ophthalmic maka ntọhapụ ọgwụ na-adịgide adịgide.
Ihe eji arụ ọrụ: Na ngalaba ihe owuwu, HPMC na-eje ozi dị ka ihe mgbakwunye dị mkpa na ngwaahịa sitere na ciment dị ka ngwa agha, ihe nrụnye, na nrapado tile.Ngwongwo njide mmiri ya na-eme ka arụ ọrụ dịkwuo mma ma gbochie ihicha oge, ebe mmetụta ya na-eme ka ọ dịkwuo mma na-eme ka ngwakọta nke ngwakọta na-agbanwe agbanwe, na-eduga n'ịkwado nke ọma na mbelata shrinkage n'elu ọgwụgwọ.
Ụlọ ọrụ nri: A na-eji HPMC na ngwaahịa nri dị ka ihe na-agbapụta, emulsifier, na stabilizer.Ọ na-enye ụdịdị a na-achọsi ike na mmetụ ọnụ n'ụdị dị iche iche, gụnyere nri, ofe, ngwaahịa mmiri ara ehi, na ihe ebe a na-eme bred.Ọzọkwa, a na-eji ihe nkiri oriri sitere na HPMC arụ ọrụ maka ịgbatị ụtọ ụtọ, ịgbatị ndụ ndụ, yana ịkwalite nkwakọ nri.
Ihe ịchọ mma: HPMC bụ ihe a na-ahụkarị na nhazi ihe ịchọ mma dị ka ude, lotions, na shampoos, ebe ọ na-arụ ọrụ dị ka ihe na-esi ísì, ihe nchikota na ihe nkiri mbụ.Ikike ya ịmepụta gels na ihe nkiri na-emepụta ihe na-eme ka mmasị dị mma nke ngwaahịa ịchọ mma na-eme ka ọ na-enye ihe ndị na-achọsi ike na rheological na ike ijide mmiri.
Ngwaahịa nlekọta onwe onye: E wezụga ihe ịchọ mma, a na-eji HPMC n'ọtụtụ ngwaahịa nlekọta onwe ya gụnyere ntacha eze, ncha, na nhazi ntutu isi.Ọdịdị ya na-edozi mmiri na-eme ka ịmepụta emulsions kwụsiri ike na nkwụsịtụ, na-eme ka arụmọrụ na mmetụta uche nke ngwaahịa ndị a dịkwuo mma.
Mmechi:
Hydroxypropyl Methylcellulose (HPMC) na-eguzo dị ka ihe atụ bụ isi nke polymer sịntetik nke sitere na cellulose eke, ma na-akwalite ya site na mgbanwe kemịkalụ maka ngwa mmepụta ihe dị iche iche.Ngwakọta ya pụrụ iche nke gụnyere hydrophilicity, viscosity modification, nhazi ihe nkiri, nkwụsi ike okpomọkụ, na biocompatibility, na-eme ka ọ dị mkpa n'ofe akụkụ dị iche iche.Site na ọgwụ ruo na ihe owuwu ụlọ, ngwaahịa nri, ihe ịchọ mma, na ihe nlekọta onwe onye, HPMC na-arụ ọrụ dị mkpa na sayensị akụrụngwa ọgbara ọhụrụ, na-eme ka mmepe nke usoro ihe ọhụrụ na ịkwalite arụmọrụ ngwaahịa.Ka nyocha na-aga n'ihu na-akọwapụta ikike ya, HPMC dị njikere idowe ọkwa ya dị ka polymer sịntetik bara ụba na nke dị mkpa n'afọ ndị na-abịa.
Oge nzipu: Mar-15-2024