HPMC (Hydroxypropyl Methyl Cellulose)thiabHPC (Hydroxypropyl Cellulose)yog ob qho tib si cellulose derivatives, dav siv nyob rau hauv kws tshuaj, khoom noj khoom haus, kev tsim kho thiab tshuaj pleev ib ce industries. Txawm hais tias ob qho tib si zoo sib xws hauv qee qhov, lawv pom tseeb sib txawv hauv cov qauv tshuaj, lub cev thiab tshuaj lom neeg, solubility thiab daim ntawv thov.
1. Cov qauv tshuaj thiab cov khoom
HPMC yog tsim los ntawm methylation thiab hydroxypropylation ntawm natural cellulose, thiab muaj methoxy (–OCH₃) thiab hydroxypropoxy (–OCH₂CHOHCH₃) pawg hauv cov molecule.
HPC yog tau los ntawm hydroxypropylation ntawm cellulose, thiab nws cov pab pawg neeg ua haujlwm tseem ceeb yog hydroxypropoxy (–OCH₂CHOHCH₃), tsis muaj methoxy.
Vim tias HPMC muaj cov pab pawg methoxy ntxiv dua li HPC, HPMC yog me ntsis hydrophobic, thaum HPC yog hydrophilic ntau dua. Tsis tas li ntawd, qhov hnyav molecular ntawm HPMC feem ntau yog siab dua, thaum qhov hnyav molecular ntawm HPC tuaj yeem tswj tau yooj yim dua, uas cuam tshuam rau cov yam ntxwv solubility thiab viscosity ntawm ob.
2. Dej solubility thiab solubility yam ntxwv
HPMC dissolves nyob rau hauv dej txias los ua ib tug pob tshab los yog translucent colloidal tov, tab sis yog insoluble nyob rau hauv dej kub. Yog li ntawd, HPMC yuav tsum tau muab tshem tawm ua ntej los yog dispersed siv txoj kev tshwj xeeb hauv qee daim ntawv thov.
HPC muaj cov dej solubility zoo thiab tuaj yeem yaj hauv dej txias thiab qee cov kuab tshuaj organic, xws li ethanol, methanol, thiab lwm yam, thiab muaj cov thickening zoo thiab cov yeeb yaj kiab tsim.
HPMC muaj cov khoom siv thermogel. Thaum qhov kub thiab txias, cov tshuaj tuaj yeem sib cais, thaum HPC feem ntau tsis tsim cov thermogel, yog li HPC muaj kev ruaj ntseg zoo dua hauv qhov kub thiab txias.
3. Viscosity thiab rheological zog
HPMC muaj viscosity ntau dua thiab feem ntau yog siv los ua cov thickener, stabilizer thiab zaj duab xis-tsim tus neeg sawv cev. Nws cov khoom rheological hauv cov kua dej yog ze rau cov kua dej pseudoplastic.
HPC muaj cov viscosity qis dua thiab tsim nyog rau cov qauv uas xav tau kom muaj dej zoo dua, xws li cov tshuaj hauv qhov ncauj thiab cov ntaub ntawv txheej.
4. Daim ntawv thov teb
Vim tias qhov sib txawv ntawm lub cev thiab tshuaj lom neeg ntawm HPMC thiab HPC, lawv ua lub luag haujlwm sib txawv hauv kev lag luam thiab cov khoom sib txawv:
Kev lag luam kws tshuaj
HPMC feem ntau yog siv los ua cov ntaub qhwv, cov ntaub ntawv tso tawm, cov khoom siv zaj duab xis rau cov tshuaj ntsiav tshuaj, thiab ua lub plhaub tivthaiv rau hollow capsules. Nws cov cuab yeej ua yeeb yaj kiab zoo thiab dej solubility ua rau nws nyiam cov khoom siv ntxiv rau kev npaj tso tawm.
HPC feem ntau yog siv los ua disintegrant, binder, solubilizer, thiab cov khoom siv bioadhesive rau cov ntsiav tshuaj, thiab tsim nyog rau kev txhim kho cov solubility thiab bioavailability ntawm cov tshuaj. Tsis tas li ntawd, HPC yog dav siv nyob rau hauv kub yaj extrusion tshuab dua HPMC.
Kev lag luam zaub mov
HPMC tuaj yeem siv ua zaub mov thickener, emulsifier, stabilizer, thiab emulsifier stabilizer rau cov tsis yog mis nyuj.
HPC feem ntau yog siv los ua zaub mov thickener, emulsifier, thiab txhim kho, thiab tsim nyog rau cov zaub mov tsis muaj piam thaj thiab calorie tsawg.
Tshuaj pleev ib ce thiab saib xyuas tus kheej
HPMC tuaj yeem siv rau hauv cov khoom tu tawv nqaij thiab tshuaj ntxuav tes ua emulsifier stabilizer.
HPC yog qhov tsim nyog rau cov khoom tu plaub hau, moisturizers thiab cov khoom tu qhov muag vim nws cov dej solubility zoo thiab lubricity.
Cov khoom siv hauv tsev
HPMC yog ib qho tseem ceeb ntawm cov txheej txheem vaj tsev, mortars, thiab putty hmoov, uas plays lub luag hauj lwm nyob rau hauv thickening, dej tuav thiab txhim kho adhesion.
HPC tsis tshua siv hauv kev tsim kho kev lag luam, tab sis tuaj yeem siv rau hauv cov dej-soluble coatings thiab cov nplaum.
5. Kev tiv thaiv ib puag ncig thiab kev nyab xeeb
HPMC thiab HPC yog muab los ntawm ntuj cellulose thiab muaj biodegradability zoo thiab kev nyab xeeb. HPMC feem ntau suav hais tias tsis muaj tshuaj lom thiab tsis ua rau khaus, thaum HPC kuj tseem siv dav hauv cov zaub mov thiab tshuaj, ua tau raws li kev nyab xeeb ntawm FDA (US Food and Drug Administration) thiab lwm cov qauv thoob ntiaj teb.
6. Cov lus qhia xaiv
Yog tias xav tau cov viscosity siab dua thiab cov yeeb yaj kiab tsim, HPMC yog qhov tsim nyog, xws li cov ntsiav tshuaj txheej, txheej txheej vaj tsev thiab lwm yam kev siv.
Yog tias xav tau kev solubility zoo dua thiab biocompatibility, HPC yog qhov tsim nyog, xws li cov tshuaj hauv qhov ncauj, kub yaj extrusion Cheebtsam, thiab lwm yam.
HPMCthiabHPCyog ob qho tib si tseem ceeb ntawm cellulose derivatives, uas txawv hauv cov qauv tshuaj, solubility, thiab daim ntawv thov. HPMC yog qhov tsim nyog rau cov viscosity siab, kub gel-forming daim ntaub ntawv xws li ntsiav tshuaj txheej thiab cov khoom siv hauv tsev, thaum HPC yog qhov tsim nyog rau kev npaj qhov ncauj, tshuaj pleev ib ce thiab khoom noj khoom haus vim nws cov dej solubility zoo thiab tsis muaj viscosity. Raws li kev xav tau tshwj xeeb, xaiv cov khoom siv zoo tuaj yeem txhim kho kev ua haujlwm thiab kev ruaj ntseg ntawm cov khoom.
Post lub sij hawm: Mar-28-2025