HPMC (Hydroxypropyl Methyl Cellulose)aHPC (Hydroxypropyl Cellulose)ʻO nā derivatives cellulose ʻelua, hoʻohana nui ʻia i ka lāʻau lapaʻau, meaʻai, kūkulu hale a me nā ʻoihana hoʻonaninani. ʻOiai ua like nā mea ʻelua i kekahi mau hiʻohiʻona, ʻokoʻa lākou i ka hoʻolālā kemika, nā waiwai kino a me nā waiwai, ka solubility a me nā wahi noi.
1. ʻO ke kinona a me nā waiwai
Hana ʻia ka HPMC e ka methylation a me ka hydroxypropylation o ka cellulose maoli, a loaʻa nā hui methoxy (–OCH₃) a me hydroxypropoxy (–OCH₂CHOHCH₃) i loko o ka mole.
Loaʻa ka HPC ma ka hydroxypropylation o cellulose, a ʻo kāna hui hana nui he hydroxypropoxy (–OCH₂CHOHCH₃), me ka ʻole o ka methoxy.
Ma muli o ka HPMC he pūʻulu methoxy hou aʻe ma mua o HPC, ʻoi aku ka hydrophobic o HPMC, a ʻoi aku ka hydrophilic o HPC. Eia kekahi, ʻoi aku ka kiʻekiʻe o ka paona molekala o HPMC, ʻoiai ʻo ke kaumaha o ka molecular HPC hiki ke hoʻomalu ʻia, e pili ana i ka solubility a me nā hiʻohiʻona viscosity o nā mea ʻelua.
2. Hiki i ka wai a me nā hiʻohiʻona
Hoʻoheheʻe ʻia ʻo HPMC i ka wai anuanu e hana i kahi ʻoluʻolu colloidal a i ʻole translucent, akā ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai wela. No laila, pono e hoʻoheheʻe ʻia ka HPMC ma mua o ka hoʻohana ʻana i nā ala kūikawā i kekahi mau noi.
Hiki ke hoʻoheheʻe ʻia ka HPC i ka wai anuanu a me kekahi mau mea hoʻoheheʻe kūlohelohe, e like me ka ethanol, methanol, a me nā mea ʻē aʻe.
He waiwai thermogel ka HPMC. Ke piʻi ka mahana, hiki ke hoʻokaʻawale ka hopena, ʻoiai ʻaʻole hana ʻo HPC i thermogel, no laila ʻoi aku ka maikaʻi o ka HPC ma nā wahi wela kiʻekiʻe.
3. Viscosity a me rheological waiwai
Loaʻa i ka HPMC ka viscosity kiʻekiʻe a hoʻohana mau ʻia ma ke ʻano he mānoanoa, stabilizer a me ka mea hana kiʻiʻoniʻoni. ʻO kona mau waiwai rheological i loko o ka hoʻonā wai e kokoke ana i nā wai pseudoplastic.
He haʻahaʻa ka viscosity o ka HPC a ʻoi aku ka maikaʻi no nā mea hoʻohua e koi ai i ka wai ʻoi aku ka maikaʻi, e like me nā lāʻau lapaʻau waha a me nā mea uhi.
4. Nā kahua noi
Ma muli o ka ʻokoʻa o nā waiwai kino a me nā kemika ma waena o HPMC a me HPC, pāʻani lākou i nā kuleana like ʻole i nā ʻoihana like ʻole a me nā huahana:
ʻoihana lāʻau lapaʻau
Hoʻohana nui ʻia ʻo HPMC ma ke ʻano he mea hoʻopaʻa, hoʻokuʻu mau ʻia, mea uhi kiʻiʻoniʻoni no nā papa lāʻau lapaʻau, a ma ke ʻano he ʻāpana pūpū no nā capsules hollow. ʻO kāna waiwai hana kiʻiʻoniʻoni maikaʻi a me ka hiki ke hoʻoheheʻe ʻia i ka wai e lilo ia i mea kōkua maikaʻi no ka hoʻomākaukau hoʻokuʻu mau.
Hoʻohana nui ʻia ʻo HPC ma ke ʻano he disintegrant, binder, solubilizer, a me nā mea bioadhesive no nā papa, a kūpono no ka hoʻomaikaʻi ʻana i ka solubility a me ka bioavailability o nā lāʻau lapaʻau. Eia kekahi, ʻoi aku ka nui o ka HPC i ka ʻenehana extrusion hoʻoheheʻe wela ma mua o HPMC.
ʻOihana meaʻai
Hiki ke hoʻohana ʻia ka HPMC ma ke ʻano he meaʻai mānoanoa, emulsifier, stabilizer, a me ka emulsifier stabilizer no ka ʻaila wai ʻole.
Hoʻohana nui ʻia ʻo HPC ma ke ʻano he mānoanoa meaʻai, emulsifier, a me ka mea hoʻomaikaʻi, a he kūpono ia no nā meaʻai ʻaʻohe kō a me nā calorie haʻahaʻa.
Nā mea hoʻonani a me ka mālama pilikino
Hiki ke hoʻohana ʻia ka HPMC i nā huahana mālama ʻili a me nā mea holoi ma ke ʻano he emulsifier stabilizer.
ʻOi aku ka maikaʻi o ka HPC no nā huahana mālama lauoho, moisturizers a me nā huahana mālama maka ma muli o kona hoʻoheheʻe wai maikaʻi a me ka lubricity.
Nā mea kūkulu hale
He mea koʻikoʻi ka HPMC o ka uhi hale kūkulu hale, morta, a me ka pauka putty, e hana ana i ka mānoanoa, paʻa wai a hoʻonui i ka pili.
Hoʻohana liʻiliʻi ʻia ka HPC i ka ʻoihana kūkulu, akā hiki ke hoʻohana ʻia i loko o nā pale wai-soluble a me nā mea hoʻopili.
5. Ka palekana a me ka palekana
Loaʻa ʻia ka HPMC a me ka HPC mai ka cellulose maoli a loaʻa iā lākou ka biodegradability maikaʻi a me ka palekana. Manaʻo ʻia ʻo HPMC he mea ʻawaʻawa ʻole a hoʻonāukiuki ʻole, ʻoiai hoʻohana nui ʻia ka HPC i ka meaʻai a me ka lāʻau lapaʻau, e hoʻokō ana i nā koi palekana o ka FDA (US Food and Drug Administration) a me nā kūlana honua ʻē aʻe.
6. Manao koho
Inā makemake ʻia ka viscosity kiʻekiʻe a me nā waiwai hana kiʻiʻoniʻoni, kūpono ʻo HPMC, e like me ka uhi ʻana i ka papa, nā uhi hale a me nā noi ʻē aʻe.
Inā makemake ʻia ka solubility maikaʻi a me ka biocompatibility, kūpono ka HPC, e like me nā lāʻau lapaʻau waha, nā mea hoʻoheheʻe wela wela, etc.
HPMCaHPCʻO ia nā derivatives cellulose koʻikoʻi, ʻokoʻa i ka hoʻolālā kemika, solubility, a me nā wahi noi. ʻOi aku ka maikaʻi o ka HPMC no ka viscosity kiʻekiʻe, nā noi hana gel wela e like me ka uhi papa a me nā mea kūkulu hale, ʻoiai ʻoi aku ka maikaʻi o ka HPC no ka hoʻomākaukau waha, nā mea hoʻonaninani a me nā mea hoʻomaikaʻi meaʻai ma muli o kona hoʻoheheʻe wai maikaʻi a me ka viscosity haʻahaʻa. Wahi a nā pono kikoʻī, hiki i ke koho ʻana i ka mea kūpono ke hoʻomaikaʻi i ka hana a me ke kūpaʻa o ka huahana.
Ka manawa hoʻouna: Mar-28-2025