Hydroxypropyl methylcellulose (HPMC)he mea koʻikoʻi ka wai-soluble cellulose derivative me ka nui o nā noi, ʻoi loa i nā lāʻau lapaʻau, nā meaʻai, nā mea hoʻonaninani, ke kūkulu ʻana a me nā ʻoihana ʻoihana ʻē aʻe. He pauda keʻokeʻo a keʻokeʻo paha ʻo HPMC, ʻono ʻole a ʻala ʻole i hoʻoheheʻe ʻia i loko o ka wai a hiki ke hana i kahi hāʻina ʻālohilohi, viscous. Hiki ke nānā ʻia kona mau hiʻohiʻona mai nā ʻano he nui e like me ke ʻano kemika, nā waiwai kino, a me nā kahua noi.
1. ʻO ke kinona a me ka hoʻomākaukau ʻana
ʻO ka HPMC kahi huahana kemika i loaʻa ma ka methylating a me ka hydroxypropylating cellulose kūlohelohe. ʻElua pūʻulu hana i loko o kona hale: ʻo ka methyl (-OCH₃) a ʻo ka hydroxypropyl kekahi (-OCH₂CHOHCH₃). ʻO ka hoʻokomo ʻia ʻana o kēia mau pūʻulu ʻelua e hoʻoheheʻe ʻia ka wai HPMC, ʻeleʻele i ka ʻili, a he ʻokoʻa ka solubility, viscosity a me nā ʻano ʻē aʻe.
Hoʻopaʻa mau ʻia ka iwi i hoʻokumu ʻia i ka cellulose i loko o ka molecular structure o HPMC, nona nā polysaccharides maoli a he biocompatibility maikaʻi a me ka biodegradability. No ka mea, aia nā pūʻulu hana like ʻole o ka mole, hiki ke hoʻoponopono ʻia kona wai solubility, viscosity a me ke kūpaʻa e like me ke ʻano o ka hopena.
2. Solubility a me ka viscosity
ʻO kahi hiʻohiʻona koʻikoʻi o HPMC ʻo kona hoʻoheheʻe wai maikaʻi. ʻO ka HPMC me nā kaumaha molekala like ʻole a me nā degere like ʻole o ka hoʻololi ʻana he ʻokoʻa ka solubility a me ka viscosity. Hiki ke hoʻoheheʻe koke ʻia ka HPMC i ka wai anuanu e hana i ka hopena colloidal paʻa, a ʻaʻole i hoʻopilikia nui ʻia e ka wai wela a me ka pH wai.
Ma muli o ke ʻano a me ke kiʻekiʻe o nā mea pani, hiki ke hoʻoponopono ʻia ka viscosity o HPMC ma kahi ākea. ʻO ka ʻōlelo maʻamau, ʻo ka hoʻonā wai o HPMC he viscosity a hiki ke hoʻohana ʻia e like me ka mānoanoa, adhesive a me ka stabilizer. Hiki ke ho'omalu 'ia ka viscosity o kona wai wai ma ka ho'ololi 'ana i kona kaumaha molekala a me ke degere o ka ho'ololi 'ana, a 'o ka laulā viscosity ma'amau mai nā haneli a hiki i nā tausani millipascals kekona (mPa s).
3. Paʻa wela
He kūpaʻa wela maikaʻi ka HPMC. Ma lalo o nā kūlana wela kiʻekiʻe, paʻa mau ke ʻano kemika a me nā waiwai kino o HPMC, a ʻoi aku ka kiʻekiʻe o kona helu heheʻe ma mua o 200°C. No laila, hana maikaʻi ia i kekahi mau noi e koi ana i nā kūlana wela kiʻekiʻe. ʻOi loa i ka ʻoihana meaʻai a me ka lāʻau lapaʻau, hiki i ka HPMC ke pale i nā kūlana kūlohelohe koʻikoʻi ke hoʻohana ʻia ma ke ʻano he mea mānoanoa a i ʻole nā mea hoʻokuʻu hoʻokuʻu.
4. Mechanical ikaika a me ka gelation
Loaʻa i ka hopena HPMC ka ikaika mechanical a me ka elasticity, a hiki ke hana i kahi ʻano gel ma lalo o kekahi mau kūlana. I kekahi mau noi ʻoihana, hoʻohana pinepine ʻia ka HPMC e hana i nā gels paʻa a i ʻole nā kiʻiʻoniʻoni, ʻoi aku ka nui ma nā kahua o ka lāʻau lapaʻau, ka meaʻai meaʻai, nā mea hoʻonaninani, a me nā mea ʻē aʻe, no ka mālama ʻana i ka hoʻokuʻu ʻana i ka lāʻau, mānoanoa, stabilization a me ka encapsulation o nā ʻāpana.
5. Biocompatibility a me ka biodegradability
No ka loaʻa ʻana o ka HPMC mai ka cellulose maoli, he biocompatibility maikaʻi kona, aneane ʻaʻohe biotoxicity, a hiki ke hoʻohaʻahaʻa koke ʻia i ke kino. Hoʻohana ʻia kēia hiʻohiʻona i mea hoʻohana maʻamau i ka ʻoihana lāʻau lapaʻau, ʻoi aku hoʻi no nā lāʻau lapaʻau waha a me nā hoʻomākaukau hoʻokuʻu hoʻomalu ʻia, hiki ke hoʻomaikaʻi i ka bioavailability o nā lāʻau lapaʻau ma ke kāohi ʻana i ka helu hoʻokuʻu o nā lāʻau lapaʻau.
6. Hana ʻili
Loaʻa i ka HPMC kekahi hana ili, hiki ke hōʻemi i ka haʻalulu o ka ʻili a hoʻonui i ka dispersibility a me ka wettability o ka wai. ʻO kēia hiʻohiʻona ka mea e hoʻohana nui ai ka HPMC i nā mea hoʻonaninani a me nā huahana mālama pilikino, e like me nā mānoanoa, emulsifiers a me nā stabilizers i loko o nā lotions, creams, shampoos a me nā huahana ʻē aʻe.
7. Nā waiwai non-ionic
'A'ole like me kekahi mau polysaccharide derivatives maoli, he non-ionic ka HPMC. ʻAʻole ia e hoʻopili me nā ion i loko o ka hopena a no laila ʻaʻole pili ʻia e nā loli i ka ʻike electrolyte. Hoʻohana nui kēia hiʻohiʻona i ka HPMC i kekahi mau noi ʻoihana kūikawā, ʻoi aku ka nui o ka paʻa ʻana o ka wai a i ʻole nā colloids no ka manawa lōʻihi, hiki i ka HPMC ke hōʻoia i ka paʻa a me ka paʻa.
8. Laulā o nā noi
ʻO kēia mau hiʻohiʻona o ka HPMC e hoʻohana nui ʻia i nā kula he nui, ʻoi aku ka nui o nā ʻano penei:
ʻOihana lāʻau lapaʻau: Hoʻohana pinepine ʻia ʻo HPMC e like me ka pūpū capsule no nā lāʻau lapaʻau, kahi mea lawe no nā lāʻau lapaʻau hoʻokuʻu mau, kahi adhesive, kahi mānoanoa, a me nā mea ʻē aʻe.
ʻOihana meaʻai: Hoʻohana nui ʻia ka HPMC i nā mea inu, jellies, ice creams, sauces a me nā meaʻai ʻē aʻe e like me ka mānoanoa, stabilizer, emulsifier a me gelling agent i ka ʻoihana meaʻai, hiki ke hoʻomaikaʻi i ka ʻono a me ke ʻano o ka huahana.
ʻO nā mea hoʻonaninani a me nā huahana mālama pilikino: Ma ke kahua hoʻonaninani, hoʻohana ʻia ʻo HPMC i nā creams, masks facial, shampoos, nā huahana mālama ʻili a me nā huahana ʻē aʻe e pāʻani i ka hana o ka mānoanoa, stabilization, emulsification a me nā hana ʻē aʻe.
ʻOihana hana: Hoʻohana pinepine ʻia ʻo HPMC ma ke ʻano he mānoanoa a me ka mea mālama wai i nā mea kūkulu hale. ʻO nā noi maʻamau e pili ana i ka mortar sima, nā tile adhesives, a me nā mea ʻē aʻe, hiki ke hoʻomaikaʻi i ka hana hana a me ke kūpaʻa waiwai.
Mahiʻai: Hiki ke hoʻohana ʻia ka HPMC ma ke ʻano he stabilizer a me ka mānoanoa i nā ʻano pesticide e kōkua i ka lāʻau e puʻunaue like i ka lepo a hoʻomaikaʻi i ka hopena o ka noi.
9. Ka palekana a me ka hoʻomau
Mai ka mea nui oHPMCmai ka cellulose maoli a loaʻa ka biodegradability maikaʻi, aia kekahi mau pono i ka pale ʻana i ke kaiapuni. Ma ke ʻano he polymer kūlohelohe, ʻo ka hana ʻana a me ka hoʻohana ʻana i ka HPMC ʻaʻole e hoʻokau i ke kaumaha nui i ke kaiapuni.
ʻO ka Hydroxypropyl methylcellulose (HPMC) he nui nā waiwai maikaʻi, e like me ka hoʻoheheʻe wai maikaʻi, ka mana viscosity, thermal stability, biocompatibility, etc. Me kona mau waiwai non-ionic, hiki ke hoʻololi i ke kino a me nā waiwai kemika, a me ke aloha kaiapuni, ua manaʻo ʻia ʻo HPMC he mea polymer maikaʻi loa. I ka hoʻomohala ʻenehana a me ka ʻenehana e hiki mai ana, loaʻa i ka HPMC ka noiʻi nui a me ka hiki ke noi.
Ka manawa hoʻouna: Dec-13-2024