HPMC (Hydroxypropyl Methyl Cellulose)kumaHPC (Hydroxypropyl Cellulose)duka abubuwan da aka samu na cellulose ne, ana amfani da su sosai a cikin magunguna, abinci, gine-gine da masana'antar kwaskwarima. Ko da yake su biyun sun yi kama da juna a wasu bangarori, a fili sun bambanta a tsarin sinadarai, kaddarorin jiki da sinadarai, narkewa da wuraren aikace-aikace.
1. Tsarin sinadaran da kaddarorin
HPMC an yi ta methylation da hydroxypropylation na halitta cellulose, kuma ya ƙunshi methoxy (-OCH₃) da hydroxypropoxy (-OCH₂CHOHCH₃) kungiyoyin a cikin kwayoyin.
Ana samun HPC ta hanyar hydroxypropylation na cellulose, kuma babban rukunin aikinsa shine hydroxypropoxy (–OCH₂CHOHCH₃), ba tare da methoxy ba.
Saboda HPMC ya ƙunshi ƙarin ƙungiyar methoxy fiye da HPC, HPMC ya ɗan fi hydrophobic, yayin da HPC ya fi hydrophilic. Bugu da ƙari, nauyin kwayoyin halitta na HPMC yawanci ya fi girma, yayin da nauyin kwayoyin HPC zai iya zama mafi sauƙi sarrafawa, wanda ke rinjayar solubility da danko halaye na biyu.
2. Ruwa mai narkewa da halaye masu narkewa
HPMC tana narkar da cikin ruwan sanyi don samar da maganin colloidal na gaskiya ko maras kyau, amma ba ya narkewa a cikin ruwan zafi. Saboda haka, HPMC yana buƙatar a riga an narkar da shi ko tarwatsa ta amfani da hanyoyi na musamman a wasu aikace-aikace.
HPC yana da kyakyawar narkewar ruwa kuma ana iya narkar da shi cikin ruwan sanyi da wasu abubuwan kaushi, irin su ethanol, methanol, da sauransu, kuma yana da kyawawan kaddarorin da ke samar da fim.
HPMC yana da kayan thermogel. Lokacin da zafin jiki ya tashi, maganin zai iya rabuwa, yayin da HPC yawanci ba ya samar da thermogel, don haka HPC yana da mafi kyawun kwanciyar hankali a cikin yanayin zafi mai girma.
3. Danko da rheological Properties
HPMC yana da ɗanko mafi girma kuma yawanci ana amfani dashi azaman mai kauri, mai daidaitawa da wakili na ƙirƙirar fim. Its rheological Properties a cikin ruwa bayani ne kusa da pseudoplastic ruwaye.
HPC yana da ƙananan danko kuma ya fi dacewa da ƙirar ƙira waɗanda ke buƙatar ingantaccen ruwa, kamar magungunan baka da kayan shafa.
4. Filayen aikace-aikace
Saboda bambance-bambancen kaddarorin jiki da sinadarai tsakanin HPMC da HPC, suna taka rawa daban-daban a masana'antu da samfuran daban-daban:
Masana'antar harhada magunguna
HPMC galibi ana amfani da shi azaman ɗaure, kayan ci gaba mai ɗorewa, kayan shafa na fim don allunan magunguna, kuma azaman ɓangaren harsashi don ƙananan capsules. Kyakkyawan kayan samar da fina-finai da rarrabuwar ruwa sun sa ya zama abin da aka fi so don shirye-shiryen ɗorewa-saki.
Ana amfani da HPC galibi azaman mai tarwatsewa, ɗaure, mai solubilizer, da kayan aikin bioadhesive don allunan, kuma ya dace don haɓaka narkewa da haɓakar ƙwayoyin cuta. Bugu da kari, HPC ne mafi yadu amfani a zafi narkewa extrusion fasaha fiye da HPMC.
Masana'antar abinci
Ana iya amfani da HPMC azaman mai kauri, emulsifier, stabilizer, da emulsifier stabilizer don kirim ɗin da ba na kiwo ba.
Ana amfani da HPC galibi azaman mai kauri, emulsifier, da haɓakawa, kuma ya dace da abinci mara sikari da ƙarancin kalori.
Kayan shafawa da kulawa na sirri
Ana iya amfani da HPMC a cikin samfuran kula da fata da wanki a matsayin mai daidaitawa.
HPC ya fi dacewa da kayan kula da gashi, masu damshi da kayan kula da ido saboda kyakkyawan narkewar ruwa da mai.
Kayan gini
HPMC wani muhimmin sashi ne na suturar gine-gine, turmi, da foda, wanda ke taka rawa wajen yin kauri, riƙe ruwa da haɓaka mannewa.
HPC ba ta da amfani a cikin masana'antar gine-gine, amma ana iya amfani da ita a cikin takamaiman sutura masu narkewa da ruwa.
5. Kariyar muhalli da aminci
Dukansu HPMC da HPC an samo su daga cellulose na halitta kuma suna da kyakkyawan yanayin halitta da aminci. Ana ɗaukar HPMC gabaɗaya a matsayin mara guba kuma mara haushi, yayin da HPC kuma ana amfani da shi sosai a abinci da magani, yana biyan bukatun aminci na FDA (Hukumar Abinci da Magunguna ta Amurka) da sauran ƙa'idodi na duniya.
6. Shawarwari na zaɓi
Idan ana buƙatar mafi girman danko da kaddarorin samar da fim, HPMC ya dace, kamar murfin kwamfutar hannu, suturar gine-gine da sauran aikace-aikace.
Idan ana buƙatar mafi kyawun solubility da biocompatibility, HPC ya dace, kamar magungunan baka, abubuwan da ke narke mai zafi, da sauransu.
HPMCkumaHPCDukansu mahimman abubuwan da suka samo asali ne na cellulose, waɗanda suka bambanta a tsarin sinadarai, solubility, da wuraren aikace-aikacen. HPMC ya fi dacewa da babban danko, aikace-aikacen gel mai zafi mai zafi irin su rubutun kwamfutar hannu da kayan gini, yayin da HPC ya fi dacewa da shirye-shiryen baka, kayan shafawa da kayan abinci na abinci saboda kyakkyawan ruwa mai narkewa da ƙananan danko. Dangane da takamaiman buƙatu, zabar kayan da ya dace na iya haɓaka aiki da kwanciyar hankali na samfurin.
Lokacin aikawa: Maris 28-2025